Post List

  • January 28, 2017
  • 07:52 PM
  • 485 views

A Model for Phage Communication and the Implications for the Human Microbiome

by Geoffrey Hannigan in Prophage

Well we took a bit of a break these past couple of weeks, but we are back for the new year! Welcome to the Prophage blog 2017! The year has actually been off to a good start, with a lot of interesting papers being published this January. This week I want to kick things off by covering a very cool 2017 study by Erez et al that described an new and interesting mechanism by which bacteriophages communicate using...... Read more »

Erez, Z., Steinberger-Levy, I., Shamir, M., Doron, S., Stokar-Avihail, A., Peleg, Y., Melamed, S., Leavitt, A., Savidor, A., Albeck, S.... (2017) Communication between viruses guides lysis–lysogeny decisions. Nature, 541(7638), 488-493. DOI: 10.1038/nature21049  

  • January 28, 2017
  • 04:26 PM
  • 511 views

RCT of traditional running shoes vs minimalist running shoes

by Craig Payne in Running Research Junkie

RCT of traditional running shoes vs minimalist running shoes... Read more »

  • January 28, 2017
  • 08:42 AM
  • 559 views

Distortions of Reality

by The Neurocritic in The Neurocritic





President Trump this week repeated an assertion he made shortly after his election: that millions of ballots cast illegally by undocumented immigrants cost him the popular vote. If true, this would suggest the wholesale corruption of American democracy.

Not to worry: As far as anyone knows, the president’s assertion is akin to saying that millions of unicorns also voted illegally.

- In a

... Read more »

Preller, K., Herdener, M., Pokorny, T., Planzer, A., Kraehenmann, R., Stämpfli, P., Liechti, M., Seifritz, E., & Vollenweider, F. (2017) The Fabric of Meaning and Subjective Effects in LSD-Induced States Depend on Serotonin 2A Receptor Activation. Current Biology. DOI: 10.1016/j.cub.2016.12.030  

Wacker, D., Wang, S., McCorvy, J., Betz, R., Venkatakrishnan, A., Levit, A., Lansu, K., Schools, Z., Che, T., Nichols, D.... (2017) Crystal Structure of an LSD-Bound Human Serotonin Receptor. Cell, 168(3), 377-2147483647. DOI: 10.1016/j.cell.2016.12.033  

  • January 28, 2017
  • 04:15 AM
  • 542 views

"Should gluten-free foods be available on prescription?"

by Paul Whiteley in Questioning Answers

Continuing the theme of blogging outside of the core material typically included on this site, I couldn't resist a mention of the 'head-to-head' debate talked about in the article by Matthew Kurien and colleagues [1] published in the British Medical Journal (BMJ).As per the title of this post, the name of the game was gluten-free products being available on prescription here in Blighty, and in particular, the prescribing of gluten-free products to patients diagnosed with coeliac disease. Th........ Read more »

Kurien M, Sleet S, Sanders DS, & Cave J. (2017) Should gluten-free foods be available on prescription?. BMJ (Clinical research ed.). PMID: 28073799  

  • January 28, 2017
  • 03:28 AM
  • 620 views

When You're Drowsy, Is Your Brain Partly Asleep?

by Neuroskeptic in Neuroskeptic_Discover

When we're feeling very tired, we sometimes remark that we're "half-asleep". But is this more than just a figure of speech? A new paper suggests that parts of our brain may actually 'fall asleep' even while we're still awake.



According to researchers Jeremy D. Slater and colleagues of the University of Texas, "local sleep" occurs throughout the human brain, with each brain region passing into and out of a sleep-like state over time. What's more, local sleep becomes more and more common in... Read more »

Slater JD, Chelaru MI, Hansen BJ, Beaman C, Kalamangalam G, Tandon N, & Dragoi V. (2017) Focal Changes to Human Electrocorticography With Drowsiness: A Novel Measure of Local Sleep. The Journal of Neuropsychiatry and Clinical Neurosciences. PMID: 28121257  

  • January 27, 2017
  • 12:27 PM
  • 417 views

Impairment of neurogenesis in ZIKV infected neuronal cells: strain specific ? Asian/American v. African strains

by thelonevirologist in Virology Tidbits

uring the current Zika Virus (ZIKV) outbreaks in the Americas, an increased number of cognitive malformations including but not limited to microcephaly in foetuses and neonates of mothers who had been infected with ZIKV during pregnancy, lead to the conclusion that ZIKV might be neuroteratogenic, a hypothesis that has been supported by findings that various ZIKV strains –including isolates from Asia such ZIKV SZ 01, ZIKV FSS13025 and H/PF/2013 as well as isolates from the Americas such as........ Read more »

Li H, Saucedo-Cuevas L, Shresta S, & Gleeson JG. (2016) The Neurobiology of Zika Virus. Neuron, 92(5), 949-958. PMID: 27930910  

van den Pol AN, Mao G, Yang Y, Ornaghi S, & Davis JN. (2017) Zika virus targeting in the developing brain. The Journal of neuroscience : the official journal of the Society for Neuroscience. PMID: 28123079  

Li H, Saucedo-Cuevas L, Regla-Nava JA, Chai G, Sheets N, Tang W, Terskikh AV, Shresta S, & Gleeson JG. (2016) Zika Virus Infects Neural Progenitors in the Adult Mouse Brain and Alters Proliferation. Cell stem cell, 19(5), 593-598. PMID: 27545505  

Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM.... (2016) Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell stem cell, 18(5), 587-90. PMID: 26952870  

Garcez PP, Nascimento JM, de Vasconcelos JM, Madeiro da Costa R, Delvecchio R, Trindade P, Loiola EC, Higa LM, Cassoli JS, Vitória G.... (2017) Zika virus disrupts molecular fingerprinting of human neurospheres. Scientific reports, 40780. PMID: 28112162  

Gabriel, E., Ramani, A., Karow, U., Gottardo, M., Natarajan, K., Gooi, L., Goranci-Buzhala, G., Krut, O., Peters, F., Nikolic, M.... (2017) Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. Cell Stem Cell. DOI: 10.1016/j.stem.2016.12.005  

Gromley A, Jurczyk A, Sillibourne J, Halilovic E, Mogensen M, Groisman I, Blomberg M, & Doxsey S. (2003) A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase. The Journal of cell biology, 161(3), 535-45. PMID: 12732615  

Meitinger F, Anzola JV, Kaulich M, Richardson A, Stender JD, Benner C, Glass CK, Dowdy SF, Desai A, Shiau AK.... (2016) 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. The Journal of cell biology, 214(2), 155-66. PMID: 27432897  

Souza BS, Sampaio GL, Pereira CS, Campos GS, Sardi SI, Freitas LA, Figueira CP, Paredes BD, Nonaka CK, Azevedo CM.... (2016) Zika virus infection induces mitosis abnormalities and apoptotic cell death of human neural progenitor cells. Scientific reports, 39775. PMID: 28008958  

  • January 27, 2017
  • 09:38 AM
  • 54 views

Does fishing influence how sensitive fish stocks are to climate?

by sceintists from the Marine group at CEES in Marine Science blog

High fishing pressure tends to lead to proportionally fewer old and large individuals in fish stocks. It is feared that these demographic changes make the fish stocks more sensitive to climate variability and change. Statistical analysis of long-term survey data on cod eggs throws new light on the possible mechanisms.



... Read more »

Stige, L., Yaragina, N., Langangen, Ø., Bogstad, B., Stenseth, N., & Ottersen, G. (2017) Effect of a fish stock's demographic structure on offspring survival and sensitivity to climate. Proceedings of the National Academy of Sciences, 201621040. DOI: 10.1073/pnas.1621040114  

  • January 27, 2017
  • 07:02 AM
  • 500 views

Swearing makes you seem more honest 

by Doug Keene in The Jury Room

But we still don’t recommend it in polite company (aka, the courtroom)! An international team of researchers (from the Netherlands, Hong Kong, the United States and the United Kingdom) have just published an article examining two perspectives on profanity and honesty. The researchers say that, on one hand, profanity is considered a violation of social […]... Read more »

Feldman, G., Lian, H., Kosinski, M., & Stillwell, D. (2017) Frankly, We Do Give a Damn: The relationship between profanity and honesty. Social Psychological and Personality Science, 2147483647. DOI: 10.1177/1948550616681055  

  • January 27, 2017
  • 05:13 AM
  • 448 views

TSC1 expression is affected by VHL alterations and HIF-1α production in clear-cell RCC

by Joana Guedes in BHD Research Blog

VHL genetic alterations do not affect the production of HIF-α in clear-cell renal cell carcinoma (ccRCC). However, their effects on tuberous sclerosis proteins (TSC1/2) and heat shock protein 90 (Hsp90) expression are currently unknown. In a recent study, Damjanovic et al. (2016) evaluated the impact of VHL genetic alterations and HIF-α production on the expression of TSC proteins and Hsp90 in 47 sporadic ccRCCs and corresponding normal tissues.... Read more »

  • January 27, 2017
  • 05:00 AM
  • 500 views

Friday Fellow: Black Bread Mold

by Piter Boll in Earthling Nature

by Piter Kehoma Boll Today’s Friday Fellow lives in our houses and our gardens, among our food and our crops. And every time we notice it, we get upset, because it means that something we were supposed to eat is … Continue reading →... Read more »

Hernández-Lauzardo, A., Bautista-Baños, S., Velázquez-del Valle, M., Méndez-Montealvo, M., Sánchez-Rivera, M., & Bello-Pérez, L. (2008) Antifungal effects of chitosan with different molecular weights on in vitro development of Rhizopus stolonifer (Ehrenb.:Fr.) Vuill. Carbohydrate Polymers, 73(4), 541-547. DOI: 10.1016/j.carbpol.2007.12.020  

  • January 27, 2017
  • 03:07 AM
  • 267 views

Vitamin D deficiency and risk of dementia

by Paul Whiteley in Questioning Answers

"The results of this systematic review show that low vitamin D levels might contribute to the development of dementia."Whilst slightly off-topic when it comes to the core research material typically included on this blog, I did want to bring to your attention the systematic review and meta-analysis results published by Isolde Sommer and colleagues [1] (open-access) for your perusal. Although unable to "identify a single study investigating the association between sunlight exposure and demen........ Read more »

Sommer I, Griebler U, Kien C, Auer S, Klerings I, Hammer R, Holzer P, & Gartlehner G. (2017) Vitamin D deficiency as a risk factor for dementia: a systematic review and meta-analysis. BMC geriatrics, 17(1), 16. PMID: 28086755  

  • January 26, 2017
  • 07:14 AM
  • 67 views

Research evaluates growth patterns of Criollo foals

by SciELO in SciELO in Perspective | Press Releases

Researchers at the Federal University of Pelotas (UFPel) in Pelotas, Rio Grande do Sul, Brazil, tested the methods of measuring growth rates of Criollo foals and showed that body height and chest circumference can be assessed by means of nonlinear models simultaneously in males and females. … Read More →... Read more »

Pimentel, A., Rodrigues, W., Martins, C., Montanez, N., Boligon, A., & Souza, J. (2017) Gender on the growth of Criollo foals from birth to three years of age. Ciência Rural, 47(1). DOI: 10.1590/0103-8478cr20150989  

  • January 26, 2017
  • 06:00 AM
  • 137 views

Mesa Verde’s Sun Temple Reveals Geometrical ‘Genius,’ Physicist Says

by Blake de Pastino in Western Digs

An 800-year-old ceremonial complex near the famous cliff dwellings of Mesa Verde was built using the same basic geometry found in ancient monuments from Greece to Egypt, a new study has found.

... Read more »

Sherry Towers. (2016) Advanced geometrical constructs in a Pueblo ceremonial site, c 1200 CE. Journal of Archaeological Science: Reports. arXiv: 1605.09494v2

  • January 26, 2017
  • 03:10 AM
  • 290 views

Andrew Whitehouse on challenging yet another autism status quo: diagnosis before intervention

by Paul Whiteley in Questioning Answers

"This paper provides an overview of the benefits and drawbacks of the current clinical pathway that places primacy on a diagnostic assessment for triggering the commencement of therapy. The paper then presents an alternative clinical pathway - the identification and provision of therapy to infants at risk of ASD [autism spectrum disorder] - and provides a critical review of current evidence supporting this model."So said the 'lecture paper' by Andrew Whitehouse [1] and, as per the titl........ Read more »

  • January 25, 2017
  • 12:06 PM
  • 276 views

Jet Lag and Baseball (MLB) Performance

by William Yates, M.D. in Brain Posts

Abrupt changes in the biological clock or circadian rhythm are noted to contribute to significant cognitive and psychomotor impairments.One practical area for this effect to potentially be important is in the area of sports performance.Alex Song and colleagues recently completed an interesting study of major league baseball (MLB) performance related to team travel patterns.The major leagues are divided into regional divisions (western, central and eastern) to minimize length of travel to and fro........ Read more »

Song A, Severini T, & Allada R. (2017) How jet lag impairs Major League Baseball performance. Proceedings of the National Academy of Sciences of the United States of America. PMID: 28115724  

  • January 25, 2017
  • 10:30 AM
  • 220 views

The Importance of Science in Horse Training

by CAPB in Companion Animal Psychology Blog

Horse ‘licking and chewing’: is it a sign of learning, submission or stress?Guest post by Georgina (Gina) Bishopp (Hartpury College, UK). A little while ago I was having a lesson on my horse when my instructor beamed up at me and exclaimed, “There you go, she is licking and chewing – she’s really listening to you now, keep going!” and with excitement I continued on eagerly with the exercise we were practising. It wasn’t until the exhilaration of the moment had waned did I thin........ Read more »

  • January 25, 2017
  • 08:10 AM
  • 275 views

A poo transplant for [some] autism?

by Paul Whiteley in Questioning Answers

I've talked about 'fecal microbial transplants' a.k.a the poo(p) transplant before on this blog (see here). That previous entry was about the more typical (and potentially life-saving) use of a poo transplant - where stool from one person is extracted, 'repackaged' and transferred to another person - albeit with caveats in terms of possible long-term side-effects. Now it appears that poo transplants are being investigated with something rather more central to the typical cont........ Read more »

  • January 25, 2017
  • 08:00 AM
  • 210 views

Asthma & Histone Acetylation: an important epigenetic mechanism in allergic diseases

by Daniel Potaczek in EpiBeat

Epigenetic regulation is thought to be one of the most important mechanisms contributing to the development and clinical course of chronic immunological diseases like allergies and asthma. DNA methylation has been extensively studied in this context, which has not been a case of histone modifications such as histone acetylation or methylation.

Early epigenetic studies from our lab conducted in mouse models demonstrated a role for histone acetylation in mediating bacteria-induced protection ag........ Read more »

Harb H, Alashkar Alhamwe B, Garn H, Renz H, & Potaczek DP. (2016) Recent developments in epigenetics of pediatric asthma. Current opinion in pediatrics, 28(6), 754-763. PMID: 27662207  

Harb, H., Amarasekera, M., Ashley, S., Tulic, M., Pfefferle, P., Potaczek, D., Martino, D., Kesper, D., Prescott, S., & Renz, H. (2016) Epigenetic Regulation in Early Childhood: A Miniaturized and Validated Method to Assess Histone Acetylation. International Archives of Allergy and Immunology, 168(3), 173-181. DOI: 10.1159/000442158  

Harb, H., Raedler, D., Ballenberger, N., Böck, A., Kesper, D., Renz, H., & Schaub, B. (2015) Childhood allergic asthma is associated with increased IL-13 and FOXP3 histone acetylation. Journal of Allergy and Clinical Immunology, 136(1), 200-202. DOI: 10.1016/j.jaci.2015.01.027  

Stefanowicz, D., Lee, J., Lee, K., Shaheen, F., Koo, H., Booth, S., Knight, D., & Hackett, T. (2015) Elevated H3K18 acetylation in airway epithelial cells of asthmatic subjects. Respiratory Research, 16(1). DOI: 10.1186/s12931-015-0254-y  

Harb, H., & Renz, H. (2015) Update on epigenetics in allergic disease. Journal of Allergy and Clinical Immunology, 135(1), 15-24. DOI: 10.1016/j.jaci.2014.11.009  

  • January 25, 2017
  • 07:02 AM
  • 230 views

Generational labels, researching emojis, and two persuasion  landmines

by Rita Handrich in The Jury Room

We read so much for this blog (and just out of general curiosity) that we often find these small bits of information which don’t justify an entire blog post but that we want to share with you because they are just too good to ignore. Here’s another one of those combination posts that you simply […]... Read more »

  • January 25, 2017
  • 04:30 AM
  • 227 views

Degenerative Changes in the Knee Joint Are Present in Elite American Football Players

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

One in 4 American Football players at the NFL Combine with a history of knee surgery have knee osteoarthritis despite being only 20 to 26 years of age.... Read more »

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.