A review of the picture of brane world and cosmology arising from string theory.... Read more »
Cumulative probability models are widely used for the analysis of ordinal data. In this article the authors propose cumulative probability mixture models that allow the assumptions of the cumulative probability model to hold within subsamples of the data. The subsamples are defined in terms of latent class membership. In the case of the ordered logit mixture model, on which the authors focus here, the assumption of a logistic distribution for an underlying latent dependent variable holds within ........ Read more »
Not all cholesterol is bad. Every cell requires it for growth – they either have to get cholesterol somewhere or they die. A sensor called sterol regulatory element-binding protein 2 (SREBP-2) monitors cellular cholesterol levels and responds to low levels by switching on genes that allow the cell to either 1) take up more from the bloodstream or 2) manufacture more from cholesterol building blocks inside the cell. Now researchers have uncovered a third cholesterol source also controlled b........ Read more »
Seo YK, Jeon TI, Chong HK, Biesinger J, Xie X, & Osborne TF. (2011) Genome-wide Localization of SREBP-2 in Hepatic Chromatin Predicts a Role in Autophagy. Cell metabolism, 13(4), 367-75. PMID: 21459322
Explores how pharyngeal pressures are effected by tongue-hold swallow. ... Read more »
Doeltgen SH, Macrae P, & Huckabee ML. (2011) Pharyngeal pressure generation during tongue-hold swallows across age groups. American journal of speech-language pathology / American Speech-Language-Hearing Association, 20(2), 124-30. PMID: 21386045
Research suggests that people are unconsciously drawn to locations and professions that resemble their names. Other aspects of names, such as uniqueness and ethnicity, also influence life outcomes.... Read more »
Pelham BW, Mirenberg MC, & Jones JT. (2002) Why Susie sells seashells by the seashore: implicit egotism and major life decisions. Journal of personality and social psychology, 82(4), 469-87. PMID: 11999918
HIV virus rapidly undergoes mutation, which is main hurdle in developing vaccine against HIV.There is a region on HIV virus which shows less variations, called as Cd4 binding site ,therefore a protein which stimulate antibody formation against this region can be developed and used as a vaccine.
Researchers at Vaccine Research Center (VRC) and the National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health have studied genes which code for such proteins which can........ Read more »
B V Waghmare. (2011) HIV vaccine development : Proteins which trains B Cells for production of antibodies which successfully neutralize HIV by binding with it . http://bvwaghmare.blogspot.com. info:/(DOI/arXiv/etc.)
xxx... Read more »
Kirsten E. Nicholson and Paul M. Richards. (2011) Home-range size and overlap within an introduced population of the Cuban Knight Anole, Anolis equestris (Squamata: Iguanidae). Phyllomedusa, 10(1), 65-73. info:/
Geoarchaeology at the fossa Carolina... Read more »
Eva Leitholdt, Christoph Zielhofer, Stefanie Berg-Hobohm, Katharina Schnabl, Britta Kopecky-Hermanns, Jens Bussmann, Joachim W. Härtling, Klaus Reicherter, & Katrin Unger. (2012) Fossa Carolina: The First Attempt to Bridge the Central European Watershed—A Review, New Findings, and Geoarchaeological Challenges. Geoarchaeology, 88-104. info:/
A new study that raised concerns about exercise should instead raise concerns about obesity.... Read more »
Claude Bouchard, Steven Blair, Timothy Church, Conrad Earnest, James Hagberg, Keijo Häkkinen, Nathan Jenkins, Laura Karavirta, William Kraus, Arthur Leon.... (2012) Adverse Metabolic Response to Regular Exercise: Is It a Rare or Common Occurrence?. PLOS One, 7(5). info:/10.1371/journal.pone.0037887
It seems that just half an hour of sleep makes a big difference when it comes to children ages 7 to 11. Researchers in Canada have found that kids who were allowed to sleep just a bit more than usual performed much better at school than kids who were deprived almost one hour of sleep over the week.... Read more »
Gruber, R., Cassoff, J., Frenette, S., Wiebe, S., & Carrier, J. (2012) Impact of Sleep Extension and Restriction on Children's Emotional Lability and Impulsivity. PEDIATRICS. DOI: 10.1542/peds.2012-0564
Recent news in cancer research points to the importance of epigenetics and cell signalling in producing complex combinational cures.... Read more »
Watson, J. (2013) Oxidants, antioxidants and the current incurability of metastatic cancers. Open Biology, 3(1), 120144-120144. DOI: 10.1098/rsob.120144
Watson J. (2013) Oxidants, antioxidants and the current incurability of metastatic cancers. Open biology, 3(1), 120144. PMID: 23303309
A fun post with commentary about a recent clinical RNAi success story.... Read more »
Coelho T, Adams D, Silva A, Lozeron P, Hawkins PN, Mant T, Perez J, Chiesa J, Warrington S, Tranter E.... (2013) Safety and efficacy of RNAi therapy for transthyretin amyloidosis. The New England journal of medicine, 369(9), 819-29. PMID: 23984729
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