Post List

  • November 4, 2016
  • 06:12 AM
  • 172 views

Two recent case reports on BHD – Epidemiologic study of patients in Asia and new FLCN mutation

by Joana Guedes in BHD Research Blog

Furuya et al. (2016) present a new study describing genetic, epidemiologic and clinicopathologic features of 312 Asian individuals with BHD manifestations based on data from 120 probands from different families (119 Japanese and 1 Taiwanese), 36 siblingss with genetic testing and 156 siblings without genetic testing.... Read more »

Furuya M, Yao M, Tanaka R, Nagashima Y, Kuroda N, Hasumi H, Baba M, Matsushima J, Nomura F, & Nakatani Y. (2016) Genetic, epidemiologic and clinicopathologic studies of Japanese Asian patients with Birt-Hogg-Dubé syndrome. Clinical genetics, 90(5), 403-412. PMID: 27220747  

  • November 4, 2016
  • 05:00 AM
  • 163 views

Friday Fellow: Silvergreen Moss

by Piter Boll in Earthling Nature

by Piter Kehoma Boll Found throughout most of the world, you probably have encountered this fellow many times in your life, but did not pay any attention. After all, it is just a moss! Scientifically known as Bryum argenteum and popularly … Continue reading →... Read more »

  • November 4, 2016
  • 04:03 AM
  • 189 views

Hyperhomocysteinemia as a significant risk factor for autism?

by Paul Whiteley in Questioning Answers

The findings reported by Naushad Shaik Mohammad and colleagues [1] provide some blogging fodder today and the suggestion of a link between some of the genetics of the folate pathway and the finding of elevated levels of homocysteine with [some] autism in mind.OK, from the start, the genetics of folate metabolism mentioned in the context of autism typically means reference to the quite well replicated finding of issues with the gene methylenetetrahydrofolate reductase (MTHFR) (see ........ Read more »

Shaik Mohammad N, Sai Shruti P, Bharathi V, Krishna Prasad C, Hussain T, Alrokayan SA, Naik U, & Radha Rama Devi A. (2016) Clinical utility of folate pathway genetic polymorphisms in the diagnosis of autism spectrum disorders. Psychiatric genetics. PMID: 27755291  

  • November 3, 2016
  • 11:10 PM
  • 206 views

Stereotyped ethnic names as a barrier to workplace entry

by Ingrid Piller in Language on the Move

Who of the three women in this image do you think German employers are most likely to consider as a...... Read more »

  • November 3, 2016
  • 01:49 PM
  • 209 views

Does The Motor Cortex Inhibit Movement?

by Neuroskeptic in Neuroskeptic_Discover

A new paper could prompt a rethink of a basic tenet of neuroscience. It is widely believed that the motor cortex, a region of the cerebral cortex, is responsible for producing movements, by sending instructions to other brain regions and ultimately to the spinal cord. But according to neuroscientists Christian Laut Ebbesen and colleagues, the truth may be the opposite: the motor cortex may equally well suppress movements.



Ebbesen et al. studied the vibrissa motor cortex (VMC) of the rat, ... Read more »

  • November 3, 2016
  • 04:10 AM
  • 220 views

Antibiotic brain part 3

by Paul Whiteley in Questioning Answers

"This study demonstrates an association between antibiotic use in the first year of life and subsequent neurocognitive outcomes in childhood."So said the findings reported by Slykerman and colleagues [1] who relied on data from the Auckland Birthweight Collaborative Study (an initiative set up to determine whether "internationally recognized risk factors for small-for-gestational-age (SGA) term babies were applicable in New Zealand") to examine the suggestion that early life antib........ Read more »

Slykerman RF, Thompson J, Waldie KE, Murphy R, Wall C, & Mitchell EA. (2016) Antibiotics in the first year of life and subsequent neurocognitive outcomes. Acta paediatrica (Oslo, Norway : 1992). PMID: 27701771  

  • November 2, 2016
  • 04:56 PM
  • 170 views

When I read things like this...

by Craig Payne in Running Research Junkie

When I read things like this...... Read more »

Hollander K, Heidt C, van der Zwaard B, Braumann KM, & Zech A. (2016) Long-Term Effects of Habitual Barefoot Running and Walking: A Systematic Review. Medicine and science in sports and exercise. PMID: 27801744  

  • November 2, 2016
  • 11:09 AM
  • 196 views

Weight Training Boosts Brain Size and Performance

by William Yates, M.D. in Brain Posts

Aerobic exercise increases brain blood flow and has demonstrated beneficial effects on cognition.The effects of weight training exercise on the brain is less frequently studied. Hence, we know little about the effect and mechanism of weight training on brain function and performance.A recent study provides some needed insight on this topic.A study by C Suo and colleagues from Australia examined the effects of resistance training and cognitive skills training on brain structure and function.The k........ Read more »

Suo C, Singh MF, Gates N, Wen W, Sachdev P, Brodaty H, Saigal N, Wilson GC, Meiklejohn J, Singh N.... (2016) Therapeutically relevant structural and functional mechanisms triggered by physical and cognitive exercise. Molecular psychiatry, 21(11), 1645. PMID: 27090304  

  • November 2, 2016
  • 10:30 AM
  • 175 views

Testing an Automated and Humane Way to Resolve Barking

by CAPB in Companion Animal Psychology Blog

Teaching a quiet behaviour using an automatic feeder is a promising solution to barking problems.Some dogs bark when their owner is out and they are left home alone. A recent study by Alexandra Protopopova  (Texas Tech University) et al investigates the effectiveness of a humane, automated approach to solving barking problems.The research was conducted because some owners use citronella or shock collars to try and prevent their dogs from barking. While the devices may sometimes work, there ........ Read more »

  • November 2, 2016
  • 08:00 AM
  • 43 views

Estrogen, Memory, & Aging: DNA methylation of the ERα promoter contributes to transcriptional differences in age across the hippocampus

by Lara Ianov in EpiBeat

Estradiol (E2) influences a number of processes that are important for maintaining healthy brain function, including memory. The ability of E2 to protect the brain and enhance or maintain memory function depends on the interaction of E2 with different estrogen receptors.1 In particular, the expression of estrogen receptor alpha (ERα) has been linked to synaptic plasticity, inflammation, and neuroprotection.2-5 Thus, it may be important that expression of ERα in the hippocampus, a bra........ Read more »

Bean LA, Ianov L, & Foster TC. (2014) Estrogen receptors, the hippocampus, and memory. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry, 20(5), 534-45. PMID: 24510074  

Adams MM, Fink SE, Shah RA, Janssen WG, Hayashi S, Milner TA, McEwen BS, & Morrison JH. (2002) Estrogen and aging affect the subcellular distribution of estrogen receptor-alpha in the hippocampus of female rats. The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(9), 3608-14. PMID: 11978836  

Benedusi V, Meda C, Della Torre S, Monteleone G, Vegeto E, & Maggi A. (2012) A lack of ovarian function increases neuroinflammation in aged mice. Endocrinology, 153(6), 2777-88. PMID: 22492304  

Merchenthaler I, Dellovade TL, & Shughrue PJ. (2003) Neuroprotection by estrogen in animal models of global and focal ischemia. Annals of the New York Academy of Sciences, 89-100. PMID: 14993043  

Zhang QG, Raz L, Wang R, Han D, De Sevilla L, Yang F, Vadlamudi RK, & Brann DW. (2009) Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 29(44), 13823-36. PMID: 19889994  

Bean LA, Kumar A, Rani A, Guidi M, Rosario AM, Cruz PE, Golde TE, & Foster TC. (2015) Re-Opening the Critical Window for Estrogen Therapy. The Journal of neuroscience : the official journal of the Society for Neuroscience, 35(49), 16077-93. PMID: 26658861  

Han X, Aenlle KK, Bean LA, Rani A, Semple-Rowland SL, Kumar A, & Foster TC. (2013) Role of estrogen receptor α and β in preserving hippocampal function during aging. The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(6), 2671-83. PMID: 23392694  

  • November 2, 2016
  • 04:30 AM
  • 188 views

What Came First the Concussion Or the Lower Extremity Musculoskeletal Injury?

by Kyle Harris in Sports Medicine Research (SMR): In the Lab & In the Field

Athletes who reported sustaining a concussion were 1.6 to 2.9 times more likely to have also sustained a lower extremity musculoskeletal injury at the end of their intercollegiate athletic careers.... Read more »

Gilbert, F., Burdette, G., Joyner, A., Llewellyn, T., & Buckley, T. (2016) Association Between Concussion and Lower Extremity Injuries in Collegiate Athletes. Sports Health: A Multidisciplinary Approach, 8(6), 561-567. DOI: 10.1177/1941738116666509  

  • November 2, 2016
  • 03:55 AM
  • 211 views

ADHD (symptoms) and pain

by Paul Whiteley in Questioning Answers

If a primary goal of medicine is to relieve pain and suffering then the paper by Andrew Stickley and colleagues [1] might provide an important insight into how medicine might be missing some important groups when it comes to the experience of pain "assessed by the degree to which it interfered with work activity in the previous month."Drawing on data from the English 2007 Adult Psychiatric Morbidity Survey (APMS) (a resource that has cropped up on this blog before), auth........ Read more »

Stickley A, Koyanagi A, Takahashi H, & Kamio Y. (2016) ADHD symptoms and pain among adults in England. Psychiatry research, 326-331. PMID: 27750114  

  • November 1, 2016
  • 11:00 AM
  • 43 views

Giant pumpkins and other massive fruits

by Alice Breda in la-Plumeria

In the form of a creepy Jack-o’-lantern frightening kids who seek for treats, or of a creamy soup in a cold fall night, pumpkins are the most distinctive fruits we find on the market stands in this season. But this fruit, in its larger variants, is also at the center of a special type of competition that takes place every year. A group of fierce farmers equipped with large scales and the heaviest products of their fields meet up to determine who among them was able to grow the largest pump........ Read more »

  • November 1, 2016
  • 09:01 AM
  • 232 views

Multiwavelength study of 20 jets that emanate from the periphery of active regions by Sargam M. Mulay et al.*

by CESRA in Solar Radio Science

Solar jets are transient phenomena observed in the solar atmosphere. They appear as sharp-edged, impulsive, and collimated flows of plasma that move outwards with a bright spot at the footpoint, which forms an ‘inverted-Y’ topology of magnetic field lines. They are observed throughout the atmosphere i.e. in the photosphere (Hα, Ca II K [...]... Read more »

Mulay et al. (2006) Multiwavelength study of 20 jets that emanate from the periphery of active regions. Astronomy . info:/

  • November 1, 2016
  • 04:09 AM
  • 229 views

On the "increasing evidence for an association between vitamin D insufficiency and depression"

by Paul Whiteley in Questioning Answers

The quote titling this brief post - "increasing evidence for an association between vitamin D insufficiency and depression" - comes from the review by Parker and colleagues [1] who seem to be no strangers to reviewing evidence on a possible link between the sunshine vitamin/hormone and depression [2].Affiliated to the Black Dog Institute in Oz ('black dog' being used as a metaphor for depression for quite a few years), the authors surveyed the quite voluminous peer-reviewed research literat........ Read more »

Parker GB, Brotchie H, & Graham RK. (2016) Vitamin D and depression. Journal of affective disorders, 56-61. PMID: 27750060  

  • October 31, 2016
  • 07:36 PM
  • 233 views

The Morning After: What We Learn from Halloween

by Aurametrix team in Aurametrix Blog

What can we learn from Halloween? A lot, judging by numerous scientific studies and less scientific surveys. Halloween could help to collect a wide range of extreme facial expressions, including highly negative situations when children discover their parents ate up all their Halloween candy. This is what was done in the recent study and an ongoing youtube challenge.  Smile! You are being watched [...] ... Read more »

  • October 31, 2016
  • 05:36 AM
  • 211 views

HBOT and autism systematically reviewed again (and the same results?)

by Paul Whiteley in Questioning Answers

"To date, there is no evidence that hyperbaric oxygen therapy improves core symptoms and associated symptoms of ASD [autism spectrum disorder]."So said the results of the review by Xiong and colleagues [1] (open-access available here) completed under the auspices of the Cochrane Collaboration, leaders in the science and publication of systematic reviews (see here for another example).Looking at the collected peer-reviewed science on the topic of hyperbaric oxygen therapy (HBOT) for aut........ Read more »

  • October 31, 2016
  • 04:30 AM
  • 184 views

Repetitive Head Impacts in Mice Suggest Cumulative Affliction

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Mild repetitive blows resulted in Alzheimer’s disease and chronic traumatic encephalopathy (CTE) like conditions in mice. Additionally, as number of head impacts increased balance coordination declined, and depressive symptoms progressed.... Read more »

  • October 31, 2016
  • 02:03 AM
  • 199 views

Room 33 Revisited

by teofilo in Gambler's House

In my post about the recent radiocarbon dating of macaw remains from Chaco Canyon, I mentioned another paper I’ve been meaning to post about. Published in 2010 by Steve Plog and Carrie Heitman of the University of Virginia, it takes a close look at burial practices at Chaco, particularly focusing on the northern burial cluster […]... Read more »

Plog, S., & Heitman, C. (2010) Hierarchy and social inequality in the American Southwest, A.D. 800-1200. Proceedings of the National Academy of Sciences, 107(46), 19619-19626. DOI: 10.1073/pnas.1014985107  

  • October 30, 2016
  • 08:54 PM
  • 198 views

Haunting Delusions of Identity

by The Neurocritic in The Neurocritic

Bugs Bunny in Hyde and Hare (1955)Delusional misidentification syndromes have fascinated filmmakers and psychiatrists alike. Afflicted individuals suffer under the false belief that persons or things around them have changed their identities or appearance. Classification schemes have varied, but a general outline includes:Capgras delusion Fregoli delusion Intermetamorphosis Subjective doublesfrom Table 1 (Ellis et al., 1994). Classification and description of the four principal delusional miside........ Read more »

Courbon, P., & Tusques, J. (1994) Illusions d'intermetamorphose et de charme. History of Psychiatry, 5(17), 139-146. DOI: 10.1177/0957154X9400501711  

Ellis, H., Luauté, J., & Retterstøl, N. (1994) Delusional Misidentification Syndromes. Psychopathology, 27(3-5), 117-120. DOI: 10.1159/000284856  

Malliaras DE, Kossovitsa YT, Christodoulou GN. (1978) Organic contributors to the intermetamorphosis syndrome. American Journal of Psychiatry, 135(8), 985-987. DOI: 10.1176/ajp.135.8.985  

Silva, A., Leong, G., & Shaner, A. (1991) The Syndrome of Intermetamorphosis. Psychopathology, 24(3), 158-165. DOI: 10.1159/000284709  

Silva, A., & Leong, G. (1994) Delusions of Psychological Change of the Self. Psychopathology, 27(6), 285-290. DOI: 10.1159/000284885  

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