Post List

  • January 24, 2016
  • 08:46 PM
  • 91 views

Recent Study Reveals Role for Bacterial Viruses in Microbiome Evolution

by Geoffrey Hannigan in Prophage

Microbial communities are fierce battlegrounds between bacteria and other microbes competing for limited resources. One method some bacteria use to kill their competitors is the production of bacteriocins...... Read more »

Nedialkova LP, Sidstedt M, Koeppel MB, Spriewald S, Ring D, Gerlach RG, Bossi L, & Stecher B. (2015) Temperate phages promote colicin-dependent fitness of Salmonella enterica serovar Typhimurium. Environmental microbiology. PMID: 26439675  

  • January 24, 2016
  • 07:16 PM
  • 101 views

http://virologytidbits.blogspot.com/2016/01/human-cytomegalovirus-hcmv-and.html

by thelonevirologist in Virology Tidbits

Human Cytomegalovirus (HCMV), the prototype member of the herpesvirus subfamily Betaherpesvirinae, is the major cause of birth defects caused by viral infections, pose a serious problem for immunocompromised patients and has more recently also been associated with the onset of artherosclerosis. Upon birth, between 0.5 and 2.5% of all newborns are infected with HCMV with up to 5% being symptomatic, i.e. presenting themselves with symptoms ranging from microcephaly, motor disabilities to chorioret........ Read more »

Shintani T, & Klionsky DJ. (2004) Autophagy in health and disease: a double-edged sword. Science (New York, N.Y.), 306(5698), 990-5. PMID: 15528435  

Decuypere JP, Parys JB, & Bultynck G. (2012) Regulation of the autophagic bcl-2/beclin 1 interaction. Cells, 1(3), 284-312. PMID: 24710477  

Espert L, Codogno P, & Biard-Piechaczyk M. (2007) Involvement of autophagy in viral infections: antiviral function and subversion by viruses. Journal of molecular medicine (Berlin, Germany), 85(8), 811-23. PMID: 17340132  

Hyttinen JM, Niittykoski M, Salminen A, & Kaarniranta K. (2013) Maturation of autophagosomes and endosomes: a key role for Rab7. Biochimica et biophysica acta, 1833(3), 503-10. PMID: 23220125  

Sun Y, Yu S, Ding N, Meng C, Meng S, Zhang S, Zhan Y, Qiu X, Tan L, Chen H.... (2014) Autophagy benefits the replication of Newcastle disease virus in chicken cells and tissues. Journal of virology, 88(1), 525-37. PMID: 24173218  

Shrivastava S, Devhare P, Sujijantarat N, Steele R, Kwon YC, Ray R, & Ray RB. (2015) Knockdown of Autophagy Inhibits Infectious Hepatitis C Virus Release by the Exosomal Pathway. Journal of virology, 90(3), 1387-96. PMID: 26581990  

Cavignac Y, & Esclatine A. (2010) Herpesviruses and autophagy: catch me if you can!. Viruses, 2(1), 314-33. PMID: 21994613  

Montagnaro, S., Ciarcia, R., Pagnini, F., De Martino, L., Puzio, M., Granato, G., Avino, F., Pagnini, U., Iovane, G., & Giordano, A. (2013) Bovine herpesvirus type 4 infection modulates autophagy in a permissive cell line. Journal of Cellular Biochemistry, 114(7), 1529-1535. DOI: 10.1002/jcb.24494  

O'Connor S, Taylor C, Campbell LA, Epstein S, & Libby P. (2001) Potential infectious etiologies of atherosclerosis: a multifactorial perspective. Emerging infectious diseases, 7(5), 780-8. PMID: 11747688  

Orvedahl A, Alexander D, Tallóczy Z, Sun Q, Wei Y, Zhang W, Burns D, Leib DA, & Levine B. (2007) HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell host , 1(1), 23-35. PMID: 18005679  

Terhune S, Torigoi E, Moorman N, Silva M, Qian Z, Shenk T, & Yu D. (2007) Human cytomegalovirus UL38 protein blocks apoptosis. Journal of virology, 81(7), 3109-23. PMID: 17202209  

Chaumorcel M, Lussignol M, Mouna L, Cavignac Y, Fahie K, Cotte-Laffitte J, Geballe A, Brune W, Beau I, Codogno P.... (2012) The human cytomegalovirus protein TRS1 inhibits autophagy via its interaction with Beclin 1. Journal of virology, 86(5), 2571-84. PMID: 22205736  

Matsuo J, Tsukumo Y, Sakurai J, Tsukahara S, Park HR, Shin-ya K, Watanabe T, Tsuruo T, & Tomida A. (2009) Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin. Cancer science, 100(2), 327-33. PMID: 19068091  

Matsuo J, Tsukumo Y, Saito S, Tsukahara S, Sakurai J, Sato S, Kondo H, Ushijima M, Matsuura M, Watanabe T.... (2012) Hyperactivation of 4E-binding protein 1 as a mediator of biguanide-induced cytotoxicity during glucose deprivation. Molecular cancer therapeutics, 11(5), 1082-91. PMID: 22402126  

Marschall M, Feichtinger S, & Milbradt J. (2011) Regulatory roles of protein kinases in cytomegalovirus replication. Advances in virus research, 69-101. PMID: 21762822  

Matsunaga K, Saitoh T, Tabata K, Omori H, Satoh T, Kurotori N, Maejima I, Shirahama-Noda K, Ichimura T, Isobe T.... (2009) Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages. Nature cell biology, 11(4), 385-96. PMID: 19270696  

Bhattacharjee B, Renzette N, & Kowalik TF. (2012) Genetic analysis of cytomegalovirus in malignant gliomas. Journal of virology, 86(12), 6815-24. PMID: 22496213  

  • January 24, 2016
  • 02:45 PM
  • 125 views

Treat the pain... or treat the depression? Carpal Tunnel Syndrome management

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

Carpal tunnel syndrome is a very common pain disorder associated with compression of the median nerve at the carpal tunnel. Approximately 139 women and 67 males per 100,000 people will report this problem over the course of one year, although this depends on the definition used. The problem with CTS is not only that it is common, but also that it affects function - it is really difficult to carry out normal daily life with a numb or tingly hand, poor grip strength (particularly in the fingertips........ Read more »

Fernández-Muñoz, J., Palacios-Ceña, M., Cigarán-Méndez, M., Ortega-Santiago, R., de-la-Llave-Rincón, A., Salom-Moreno, J., & Fernández-de-las-Peñas, C. (2016) Pain is Associated to Clinical, Psychological, Physical, and Neurophysiological Variables in Women With Carpal Tunnel Syndrome. The Clinical Journal of Pain, 32(2), 122-129. DOI: 10.1097/AJP.0000000000000241  

  • January 24, 2016
  • 01:52 PM
  • 125 views

60 genetic disorders affect skin and nervous system

by Dr. Jekyll in Lunatic Laboratories

One of the most common genetic disorders is a condition called neurofibromatosis, which causes brown spots on the skin and benign tumors on the brain, spinal cord and other parts of the nervous system. Neurofibromatosis is one of at least 60 genetic diseases called neurocutaneous disorders that involve the skin, central nervous system, and/or peripheral nervous system.

... Read more »

Figueiredo, A., Mata-Machado, N., McCoyd, M., & Biller, J. (2016) Neurocutaneous Disorders for the Practicing Neurologist: a Focused Review. Current Neurology and Neuroscience Reports, 16(2). DOI: 10.1007/s11910-015-0612-7  

  • January 24, 2016
  • 12:56 PM
  • 65 views

Genes Identified That May Predispose Some Individuals to Getting Sick

by Marie Benz in MedicalResearch.com

  MedicalResearch.com Interview with: Ephraim L. Tsalik, MD MHS PhD Assistant Professor of Medicine Division of Infectious Diseases Center for Applied Genomics & Precision Medicine Duke University Medical Center Emergency Department Service Line Durham VA Medical Center  Medical Research: What … Continue reading →
The post Genes Identified That May Predispose Some Individuals to Getting Sick appeared first on MedicalResearch.com.
... Read more »

Dr. Ephraim L. Tsalik. (2016) Genes Identified That May Predispose Some Individual to Getting Sick. MedicalResearch.com. info:/

  • January 24, 2016
  • 11:17 AM
  • 106 views

Will climate change lead to more blizzards?

by dominicwhite in Two Degrees or Under

Snowstorms like the one that hit the east coast of North America this weekend are sometimes used by climate sceptics to argue that global warming is a hoax. “Surely we wouldn’t have seen 2 feet of snow if the temperature...... Read more »

  • January 24, 2016
  • 10:01 AM
  • 73 views

Increased Short Term Risk of Adverse Cardiac Effects With Antibiotic Clarithromycin

by Marie Benz in MedicalResearch.com

More on Heart Disease on MedicalResearch.com MedicalResearch.com Interview with: Professor Ian C K Wong Fellow of Royal Pharmaceutical Society Fellow of Royal College of Paediatrics and Child Health (Honorary) Fellow of the Higher Education Academy Chair in Pharmacy Practice Head … Continue reading →
The post Increased Short Term Risk of Adverse Cardiac Effects With Antibiotic Clarithromycin appeared first on MedicalResearch.com.
... Read more »

Prof. Ian CK Wong. (2016) Increased Short Term Risk of Adverse Cardiac Effects With Antibiotic Clarithromycin. MedicalResearch.com. info:/

  • January 24, 2016
  • 07:47 AM
  • 109 views

Safety devices can result in increased dangerous activities

by Usman Paracha in SayPeople

Main Point:

Dangerous activities of a person can be increased with the use of safety equipments as, for example, “wearing a bicycle helmet can increase risk taking and sensation seeking in adults.”

Published in:

Psychological Science

Study Further:

In a study, researchers from the University of Bath’s department of psychology have reported that humans develop their risk-taking behavior on the basis of the use of safety equipments.

They worked with some people ........ Read more »

  • January 23, 2016
  • 08:31 PM
  • 70 views

Virtual Tumor Model Allows Precision Treatment of Glioblastomas

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. Chirag Patil, MD American Board Certified Neurosurgeon Brain & Spine Tumor Program Lead Investigator, Precision Medicine Initiative Against Brain Cancer Program Director, Neurosurgical Residence training program Director, Center for Neurosurgical Outcomes Research Cedars-Sinai Medical Center, Los … Continue reading →
The post Virtual Tumor Model Allows Precision Treatment of Glioblastomas appeared first on MedicalResearch.com.
... Read more »

Dr. Chirag Patil, MD. (2016) Virtual Tumor Model Allows Precision Treatment of Glioblastomas. MedicalResearch.com. info:/

  • January 23, 2016
  • 04:16 PM
  • 66 views

Nearly 1/3 of Elderly Receive Non-Recommended Cancer Screening Tests

by Marie Benz in MedicalResearch.com

More on Cancer Research on MedicalResearch.com MedicalResearch.com Interview with: Firas Abdollah, M.D., F.E.B.U. (Fellow of European Board of Urology) Urology Fellow with the Center for Outcomes Research, Analytics and Evaluation Vattikuti Urology Institute at Henry Ford Hospital in Detroit  MedicalResearch: … Continue reading →
The post Nearly 1/3 of Elderly Receive Non-Recommended Cancer Screening Tests appeared first on MedicalResearch.com.
... Read more »

Firas Abdollah, M.D., F.E.B.U. (2016) Nearly 1/3 of Elderly Receive Non-Recommended Cancer Screening Tests. MedicalResearch.com. info:/

  • January 23, 2016
  • 02:26 PM
  • 155 views

When the music stops: Intensive instrument playing can lead to movement disorders

by Dr. Jekyll in Lunatic Laboratories

A musician takes up his/her violin and starts to play, but rather than gripping the strings, the fingers seize up--and this happens every time he/she takes up the instrument. Such a movement disorder--the so-called focal dystonia-- is a dramatic disease for those affected, which has thus far barely been studied.

... Read more »

Rozanski VE, Rehfuess E, Bötzel K, Nowak D. (2015) Task-specific dystonia in professional musicians—a systematic review of the importance of intensive playing as a risk factor. Dtsch Arztebl Int. info:/10.3238/arztebl.2015.0871

  • January 23, 2016
  • 10:15 AM
  • 58 views

Cardiac Groups Outline Appropriate Imaging For Chest Pain in ER

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Frank J. Rybicki, MD, PhD Professor, Chair and Chief, Department of Radiology The University of Ottawa, Faculty of Medicine and The Ottawa Hospital Editor-in-Chief, 3D Printing in Medicine Medical Research: What is the background for this document? Dr. … Continue reading →
The post Cardiac Groups Outline Appropriate Imaging For Chest Pain in ER appeared first on MedicalResearch.com.
... Read more »

Frank J. Rybicki, MD, PhD. (2016) Cardiac Groups Outline Appropriate Imaging For Chest Pain in ER. MedicalResearch.com. info:/

  • January 23, 2016
  • 05:35 AM
  • 136 views

22q11.2 Deletion Syndrome and 'a highly increased risk of schizophrenia spectrum disorders'

by Paul Whiteley in Questioning Answers

22q11.2 deletion syndrome has turned out to be something of real interest to this blog. Not only because of the reported connection to the presentation of autism (see here) including some suggestion of a role for the immune system (see here) but also because of the idea that certain somatic comorbidity linked to the gastrointestinal (GI) tract might also figure as part of the presentation of at least some cases of Del22 (see here). Said GI issues have also cropped up across quite a few other lab........ Read more »

  • January 23, 2016
  • 12:25 AM
  • 131 views

Top four threats to the ocean, according to marine scientists

by TakFurTheKaffe in Tak Fur The Kaffe

Overfishing, global warming, waste and contamination, and ocean acidification are at the forefront of scientists concerns.... Read more »

  • January 22, 2016
  • 07:33 PM
  • 42 views

Acupuncture No Better Than Placebo For Hot Flashes

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Carolyn Ee, MBBS Department of General Practice University of Melbourne Carlton, Victoria, Australia Medical Research: What is the background for this study? What are the main findings? Response: Hot flushes affect up to 90% of women during the … Continue reading →
The post Acupuncture No Better Than Placebo For Hot Flashes appeared first on MedicalResearch.com.
... Read more »

Dr. Carolyn Cheng-Ling Fe. (2016) Acupuncture No Better Than Placebo For Hot Flashes. MedicalResearch.com. info:/

  • January 22, 2016
  • 06:45 PM
  • 44 views

Proposed Model Clarifies Ovarian Risk Assessment By Ultrasound

by Marie Benz in MedicalResearch.com

More on Ovarian Cancer on MedicalResearch.com MedicalResearch.com Interview with: Dirk Timmerman, MD PhD Department of Development and Regeneration Department of Obstetrics and Gynecology University Hospitals Leuven Leuven, Belgium Medical Research: What is the background for this study? What are the … Continue reading →
The post Proposed Model Clarifies Ovarian Risk Assessment By Ultrasound appeared first on MedicalResearch.com.
... Read more »

Dirk Timmerman, MD PhD. (2016) Proposed Model Clarifies Ovarian Risk Assessment By Ultrasound. MedicalResearch.com. info:/

  • January 22, 2016
  • 06:15 PM
  • 52 views

SAD? No Relationship Between Sunlight and Depression

by Marie Benz in MedicalResearch.com

More on Depression on MedicalResearch.com MedicalResearch.com Interview with: Prof. Steven LoBello, Professor of Psychology Auburn University at Montgomery Study co-authors: Megan Traffanstedt (graduate student) and Dr. Sheila Mehta Medical Research: What is the background for this study? What are the main … Continue reading →
The post SAD? No Relationship Between Sunlight and Depression appeared first on MedicalResearch.com.
... Read more »

Prof. Steven LoBello, Professor of Psychology. (2016) SAD? No Relationship Between Sunlight and Depression. MedicalResearch.com. info:/

  • January 22, 2016
  • 02:50 PM
  • 152 views

Neurons in your gut help the immune system keep inflammation in check

by Dr. Jekyll in Lunatic Laboratories

The immune system exercises constant vigilance to protect the body from external threats–including what we eat and drink. A careful balancing act plays out as digested food travels through the intestine. Immune cells must remain alert to protect against harmful pathogens like Salmonella, but their activity also needs to be tempered since an overreaction can lead to too much inflammation and permanent tissue damage.

... Read more »

  • January 22, 2016
  • 02:08 PM
  • 45 views

Reduced Mortality With Specialized Oral Nutrition In Malnourished Older Adults

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. Refaat Hegazi, MD, PhD MS MPH Abbott medical director and study author MedicalResearch: What is the background for this study? What are the main findings? Dr. Hegazi: The NOURISH study that was recently published in Clinical … Continue reading →
The post Reduced Mortality With Specialized Oral Nutrition In Malnourished Older Adults appeared first on MedicalResearch.com.
... Read more »

Dr. Refaat Hegazi, MD, PhD MS MPH. (2016) Reduced Mortality and Readmissions With Specialized Oral Nutrition In Malnourished Older Adults. MedicalResearch.com. info:/

  • January 22, 2016
  • 11:25 AM
  • 30 views

Thyroid Gland’s Importance Recognized During Thyroid Awareness Month

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Marita Teng, MD Associate Professor of Otolaryngology Head and Neck Institute Icahn School of Medicine at Mount Sinai MedicalResearch.com Editor’s note: January is Thyroid Awareness Month. In recognition, Dr. Teng discusses the thyroid gland’s important role in the … Continue reading →
The post Thyroid Gland’s Importance Recognized During Thyroid Awareness Month appeared first on MedicalResearch.com.
... Read more »

Marita Teng, MD. (2016) Thyroid Gland's Importance Recognized During Thyroid Awareness Month. MedicalResearch.com. info:/

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.