Post List

  • August 31, 2014
  • 05:34 PM
  • 73 views

Mushroom extracts might prevent dental cavities

by Valerie Ashton in The Molecular Scribe

Recently published research suggests red camphor mushroom extracts might prevent the proliferation of bacteria that cause dental cavities and gum disease.... Read more »

  • August 31, 2014
  • 05:20 PM
  • 91 views

Heroin’s Anthrax Problem

by Rebecca Kreston in BODY HORRORS

Anthrax is a deadly disease with high rates of morbidity and mortality. Because it is, thankfully, also quite rare, it is relatively easy to track its whereabouts and going-ons when an outbreak occurs. Typically, outbreaks of anthrax have been traced to groups of people involved in high-risk activities involving grazing animals and their byproducts: anthrax favors shepherds, butchers, wool-sorters, leather workers, and even the odd drum-playing hippies. In 2009, however, an outbreak upended this........ Read more »

  • August 31, 2014
  • 02:38 PM
  • 99 views

New Synthetic Amino Acid for a New Class of Drugs

by Gabriel in Lunatic Laboratories

Creating new drug molecules is challenging, developing drugs that are highly effective against a target, but with minimal (or no) toxicity and side-effects to the patient can be an exercise in futility. These drug properties are directly conferred by the 3D structure of the drug molecule. So ideally, the drug should have a shape that is perfectly complementary to a disease-causing target, so that it binds it with high specificity.With that, scientists have developed a synthetic amino acid that c........ Read more »

Chen S. Gopalakrishnan R, Schaer T, Marger F, Hovius R, Bertrand D, Pojer F, Heinis C. (2014) Di-thiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides. Nature Chemistry. info:/10.1038/nchem.2043

  • August 30, 2014
  • 02:54 PM
  • 130 views

Direct mind-to-mind communication in humans

by Shelly Fan in Neurorexia

Image credit: www.techspot.com Here’s something right out of science fiction: a team of neuroscientists in Spain developed a system that allows a person to transmit the...... Read more »

Grau C, Ginhoux R, Riera A, Nguyen TL, Chauvat H, Berg M, Amengual JL, Pascual-Leone A, & Ruffini G. (2014) Conscious Brain-to-Brain Communication in Humans Using Non-Invasive Technologies. PloS one, 9(8). PMID: 25137064  

  • August 30, 2014
  • 02:23 PM
  • 97 views

Predictor of Sudden Death helps identify ICD candidates

by Gabriel in Lunatic Laboratories

New guidelines for patients with hypertrophic cardiomyopathy (HCM) identify candidates for implantable cardioverter defibrillators (ICDs). These devices help protect patients from arrhythmias (an irregular heartbeat) which can limit blood flow to vital organs, like the brain for example. Identifying which pacents would benefit from an ICD has been difficult. But the new guidelines, which were recently published, will help determine the patients most likely to benefit from ICDs by testing to see ........ Read more »

Perry M. Elliott, (Chairperson) (UK)*, Aris Anastasakis, (Greece), Michael A. Borger, (Germany), Martin Borggrefe, (Germany), Franco Cecchi, (Italy), Philippe Charron, (France), Albert Alain Hagege, (France), Antoine Lafont, (France), Giuseppe Limongelli,. (2014) 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC). European Heart Journal . info:/10.1093/eurheartj/ehu284

  • August 30, 2014
  • 08:12 AM
  • 105 views

The Myth Of “Roid Rage”?

by Neuroskeptic in Neuroskeptic_Discover

Are men who inject testosterone and other anabolic steroids at risk of entering a violent “roid rage“? Many people think so. Whenever a professional athlete commits a violent crime, it’s not long before someone suggests that steroids may have been involved. The most recent example of this is the case of Jonathan “War Machine” Koppenhaver. […]The post The Myth Of “Roid Rage”? appeared first on Neuroskeptic.... Read more »

  • August 30, 2014
  • 03:34 AM
  • 101 views

Under-recognised co-occurring conditions in autism

by Paul Whiteley in Questioning Answers

A brief post to direct you to the paper by Nicolaidis and colleagues [1] talking about primary care for adults on the autism spectrum and mention of an issue quite important to this blog: "the recognition of associated conditions"."When 900 years old you reach, look as good you will not".Alongside the announcement of what seems like an interesting workshop organised by the US IACC (Interagency Autism Coordinating Committee) titled: "IACC Workshop on Under-Recognized Co-Occurring Condit........ Read more »

Nicolaidis C, Kripke CC, & Raymaker D. (2014) Primary Care for Adults on the Autism Spectrum. The Medical clinics of North America, 98(5), 1169-1191. PMID: 25134878  

  • August 30, 2014
  • 03:31 AM
  • 44 views

Neurobiological Basis of Music Therapy

by Vivek Misra in The UberBrain

The basic and one of oldest socio-cognitive domains of Human species is music. Listening to music regularly helps to keep the neurons and synapses more active. Depending on the way sound waves are heard or pronounced, they have an impact in the way neurological (brain and nerve) system work in the human body. Neurological studies have identified that music is a valuable tool for evaluating the brain system [1]. Its observed that while listening to music, different parts of the brain are involved........ Read more »

Peretz, I., & Zatorre, R. (2005) Brain Organization for Music Processing. Annual Review of Psychology, 56(1), 89-114. DOI: 10.1146/annurev.psych.56.091103.070225  

Patton, J., Routh, D., & Stinard, T. (2013) Where do children study? Behavioral observations. Bulletin of the Psychonomic Society, 24(6), 439-440. DOI: 10.3758/BF03330575  

Chan AS, Ho YC, & Cheung MC. (1998) Music training improves verbal memory. Nature, 396(6707), 128. PMID: 9823892  

TSANG, C., TRAINOR, L., SANTESSO, D., TASKER, S., & SCHMIDT, L. (2006) Frontal EEG Responses as a Function of Affective Musical Features. Annals of the New York Academy of Sciences, 930(1), 439-442. DOI: 10.1111/j.1749-6632.2001.tb05764.x  

Luu P, Tucker DM, & Makeig S. (2004) Frontal midline theta and the error-related negativity: neurophysiological mechanisms of action regulation. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 115(8), 1821-35. PMID: 15261861  

Koelsch S. (2010) Towards a neural basis of music-evoked emotions. Trends in cognitive sciences, 14(3), 131-7. PMID: 20153242  

  • August 29, 2014
  • 08:36 PM
  • 97 views

Foot Orthotics and Patellofemoral Pain

by Craig Payne in Running Research Junkie

Foot Orthotics and Patellofemoral Pain... Read more »

  • August 29, 2014
  • 07:15 PM
  • 101 views

A change of mind: from bitter recollections to sweet memories

by Shelly Fan in Neurorexia

There are a LOT of articles on this study already, but most don’t go into the technical details – the part that, in my opinion,...... Read more »

  • August 29, 2014
  • 05:00 PM
  • 61 views

Visualizing the evolution of a scientific conference with altmetrics

by Peter Kraker in Science and the Web

From September 3 to 5, I will be attending STI 2014, the 19th International Conference on Science and Technology Indicators. There, I will present a paper entitled “Altmetrics-based Visualizations Depicting the Evolution of a Knowledge Domain” that I co-authored with Philipp Weißensteiner and Peter Brusilovsky (download the PDF here). In this work-in-progress paper, we present an approach to visualizing the topical evolution of a scientific conference over time.... Read more »

Kraker, P., Weißensteiner, P., & Brusilovsky, P. (2014) Altmetrics-based Visualizations Depicting the Evolution of a Knowledge Domain. 19th International Conference on Science and Technology Indicators (STI 2014), 330-333. info:/

  • August 29, 2014
  • 03:10 PM
  • 100 views

The Ever Mutating Ebola Virus

by Gabriel in Lunatic Laboratories

Ebola has a nasty reputation for the way it damages the body. It's rightfully earned when you look at the death rate. But when you look at the actual details of an Ebola infection, a surprising fact surfaces: The virus isn't what ends up killing you, it's your own immune system. Sure they are trying different ways to outsmart the virus, but it's mutating... quickly. In fact, scientists have rapidly sequenced and analyzed more than 99 Ebola virus genomes. The hope it to better understand the enem........ Read more »

Gire, S., Goba, A., Andersen, K., Sealfon, R., Park, D., Kanneh, L., Jalloh, S., Momoh, M., Fullah, M., Dudas, G.... (2014) Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science. DOI: 10.1126/science.1259657  

  • August 29, 2014
  • 01:31 PM
  • 82 views

August 29, 2014

by Erin Campbell in HighMag Blog

Stem cells in adults are responsible for tissue renewal and many cancers. So, the hunt for stem cells is important and has already been successful, with stem cell populations identified in countless types of tissues. Stem cells in the ovary, however, were shy to show themselves until a recent study using a marker for the Wnt protein Lgr5.In adults, stem cells are responsible for maintaining homeostasis during normal wear and tear of a tissue. The ovary and its ovary surface epithelium (OSE) expe........ Read more »

Ng, A., Tan, S., Singh, G., Rizk, P., Swathi, Y., Tan, T., Huang, R., Leushacke, M., & Barker, N. (2014) Lgr5 marks stem/progenitor cells in ovary and tubal epithelia. Nature Cell Biology, 16(8), 745-757. DOI: 10.1038/ncb3000  

  • August 29, 2014
  • 12:27 PM
  • 58 views

The psychology of wearable computing - does Google Glass affect where people look?

by BPS Research Digest in BPS Research Digest

Computing eyewear such as Google Glass can record information far more discreetly than a handheld camera. As a result, privacy concerns have been raised, whether in a bar or changing for the gym. Are users of this tech likely to use their new toys responsibly? Early research was promising, suggesting that the very act of recording our gaze may lead us to be extra considerate in where we look. Unfortunately a new study finds that while wearing gaze-monitoring devices may initially encourage ........ Read more »

Nasiopoulos, E., Risko, E., Foulsham, T., & Kingstone, A. (2014) Wearable computing: Will it make people prosocial?. British Journal of Psychology. DOI: 10.1111/bjop.12080  

  • August 29, 2014
  • 12:00 PM
  • 53 views

Replication and reputation: Whose career matters?

by Dorothy Bishop in bishopblog

This post is a commentary on a piece by Matthew Lieberman in Edge, in which he expresses concerns about the way in which researchers are undertaking replication studies. He argues that some people are making careers out of trying to disprove others, and in so doing are damaging science.
I argue that we need to develop a more mature understanding that the move towards more replication is not about making or breaking careers: it is about providing an opportunity to move science forward, improve o........ Read more »

  • August 29, 2014
  • 09:26 AM
  • 84 views

Breaking research: A study in fruit flies finds a possible drug target to compensate for symptoms of Parkinson’s disease

by Bethany Christmann in Fly on the Wall

Parkinson’s disease is caused by the progressive death of neurons important for movement and results in symptoms such as shaking or rigidity in the limbs, slow movements, and difficulty walking. The primary treatment is a drug called L-Dopa, which compensates for the neuron loss but eventually becomes less effective as more and more neurons die […]... Read more »

  • August 29, 2014
  • 09:25 AM
  • 120 views

The Friday Five for 8/29/14

by Bill Sullivan in The 'Scope

5 of the hottest science news stories this week include a lab-grown thymus, big Alzheimer’s news, and how to make the perfect pizza.... Read more »

  • August 29, 2014
  • 09:09 AM
  • 79 views

Folliculin function is highly cell-specific

by Lizzie Perdeaux in BHD Research Blog

Whilst trying to elucidate the role of FLCN, a number of studies have reported opposing results. FLCN has been shown to both activate and inhibit mTOR signalling, AMPK signalling and RhoA signalling and to both potentiate and abrogate cell-cell adhesion. … Continue reading →... Read more »

Khabibullin D, Medvetz DA, Pinilla M, Hariharan V, Li C, Hergrueter A, Laucho Contreras M, Zhang E, Parkhitko A, Yu JJ.... (2014) Folliculin regulates cell-cell adhesion, AMPK, and mTORC1 in a cell-type-specific manner in lung-derived cells. Physiological reports, 2(8). PMID: 25121506  

  • August 29, 2014
  • 06:38 AM
  • 114 views

Fish with Lungs Gives Clues to the Origin of Tetrapods

by beredim in Strange Animals

Juvenile Polypterus senegalusAbout 400 million years ago, fish left the water and began to evolve into land-living creatures. But how did this transition happen? In a new and unusual study, researchers from the McGill University took a fish species known to be able to occasionally walk using its fins and raised it on land. The scientists found that when raised on land, this primitive strange fish with lungs, walks much better than its water-raised friends. The experiment could she........ Read more »

  • August 29, 2014
  • 03:52 AM
  • 143 views

Oxytocin and autism: the hype?

by Paul Whiteley in Questioning Answers

Consider some excerpts from two recent papers looking at oxytocin (OXT) - the "love hormone"(!) - and the autism spectrum disorders (ASDs)...“It’s not the years, honey. It’s the mileage”"These findings indicate that dysregulated OXT biology is not uniquely associated with ASD social phenotypes as widely theorized, but instead variation in OXT biology contributes to important individual differences in human social functioning, including the severe social impairments which characterize ASD........ Read more »

Parker, K., Garner, J., Libove, R., Hyde, S., Hornbeak, K., Carson, D., Liao, C., Phillips, J., Hallmayer, J., & Hardan, A. (2014) Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1402236111  

Guastella AJ, Gray KM, Rinehart NJ, Alvares GA, Tonge BJ, Hickie IB, Keating CM, Cacciotti-Saija C, & Einfeld SL. (2014) The effects of a course of intranasal oxytocin on social behaviors in youth diagnosed with autism spectrum disorders: a randomized controlled trial. Journal of child psychology and psychiatry, and allied disciplines. PMID: 25087908  

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