Post List

  • June 13, 2016
  • 10:51 AM
  • 163 views

The best of both worlds

by SciELO in SciELO in Perspective

Quality is an ill-defined concept with regard to scholarly literature. Some aspects of quality can be assessed reasonably objectively, and immediately, such as the quality of presentation. But some cannot be readily determined, and need time and ‘digestion’ by the scholarly community, such as the scientific quality of an article. And then there is the quality of a journal’s service to authors, of particular importance for open access publishing that is supported by Article Processing Charg........ Read more »

  • June 13, 2016
  • 07:24 AM
  • 138 views

Collateral Damage: Anti-cancer therapy and Autoimmune disease: Part I

by AG McCluskey in Zongo's Cancer Diaries

This post describes what Autoimmune diseases are. Part II will describe the potential of anti-cancer therapies as treatments for Autoimmune disease.... Read more »

Bell, E., & Bird, L. (2005) Autoimmunity. Nature, 435(7042), 583-583. DOI: 10.1038/435583a  

AG McCluskey. (2016) Collateral Damage. Zongo's Cancer Diaries. info:/

  • June 13, 2016
  • 07:02 AM
  • 152 views

Maladaptive daydreaming: The next legal defense theory? 

by Doug Keene in The Jury Room

Remember Walter Mitty? He was a fictional character who escaped his dull day-to-day existence by constructing elaborate daydreams wherein he was the hero rather than a wallflower. Well, apparently Walter was not so unusual. There are people who spend as much as 60% of their time lost in daydreams. These are people who realize their […]

Related posts:
Can you trust the results of forensic evaluations on legal sanity?
Legal decisions that tick jurors off
Will your genetic defense for that........ Read more »

  • June 13, 2016
  • 02:34 AM
  • 154 views

A gluten-free diet, gastrointestinal issues and autism

by Paul Whiteley in Questioning Answers

Given my own research interest in the use of specific dietary modifications as possible intervention tools for some aspects of some autism (see here) I was more than interested to read the results published by Faezeh Ghalichi and colleagues [1] following their randomised-controlled trial of a gluten-free diet (GFD) including some 80 children diagnosed with an autism spectrum disorder (ASD).As part of an area of much discussion, debate and also heated argument down the years, the author........ Read more »

  • June 12, 2016
  • 10:35 PM
  • 199 views

Seeing Through the Skin

by Aurametrix team in Olfactics and Diagnostics

​Human skin emits light (albeit the glow is extremely weak) and a wide variety of small molecules that may be sometimes "sniffed" by dogs or even other humans. These chemicals tell a story about our health and wellness, things we eat and drink, touch and breathe. Mosquitoes use such emissions to assess our "attractiveness" from indicators such as Indoles (unpleasantly smelling but healthy "inner soil" biomarker) or carbon dioxide (amount of which correlates with the size of the person........ Read more »

Gao W, Emaminejad S, Nyein HY, Challa S, Chen K, Peck A, Fahad HM, Ota H, Shiraki H, Kiriya D.... (2016) Fully integrated wearable sensor arrays for multiplexed in situ perspiration analysis. Nature, 529(7587), 509-14. PMID: 26819044  

Yokota T, Zalar P, Kaltenbrunner M, Jinno H, Matsuhisa N, Kitanosako H, Tachibana Y, Yukita W, Koizumi M, & Someya T. (2016) Ultraflexible organic photonic skin. Science advances, 2(4). PMID: 27152354  

  • June 12, 2016
  • 02:23 PM
  • 184 views

Researchers show copper is essential for burning fat

by Dr. Jekyll in Lunatic Laboratories

Is copper deficiency contributing to the obesity epidemic? Though small amounts of copper are essential to health - oysters, liver, beans and nuts are good sources - copper's role in metabolism has been unclear: Some studies found that it boosted fat burning, others that it depressed it.

... Read more »

Krishnamoorthy, L., Cotruvo, J., Chan, J., Kaluarachchi, H., Muchenditsi, A., Pendyala, V., Jia, S., Aron, A., Ackerman, C., Wal, M.... (2016) Copper regulates cyclic-AMP-dependent lipolysis. Nature Chemical Biology. DOI: 10.1038/nchembio.2098  

  • June 11, 2016
  • 10:02 PM
  • 142 views

Natural Selection, Sexual Selection, and Chameleons

by Emily Makowski in Sextraordinary!

I discuss an upcoming article on how natural selection and sexual selection affect the courtship behavior of the common chameleon.... Read more »

Keren-Rotem, T., Levy, N., Wolf, L., Bouskila, A., & Geffen, E. (2016) Male preference for sexual signalling over crypsis is associated with alternative mating tactics. Animal Behaviour, 43-49. info:/http://dx.doi.org/10.1016/j.anbehav.2016.04.021

  • June 11, 2016
  • 05:29 AM
  • 232 views

The Four-Dimensional Brain?

by Neuroskeptic in Neuroskeptic_Discover

"The brain is a three dimensional object." It would seem that this is one of the least controversial facts about the brain, something we can all agree on. But now, in a curious new paper, researchers Arturo Tozzi and James F. Peters suggest that the brain might have an extra dimension: Towards a fourth spatial dimension of brain activity


From topology, a strong concept comes into play in understanding brain functions, namely, the 4D space of a ‘‘hypersphere’s torus’’, undetectable by........ Read more »

Tozzi A, & Peters JF. (2016) Towards a fourth spatial dimension of brain activity. Cognitive neurodynamics, 10(3), 189-99. PMID: 27275375  

  • June 11, 2016
  • 03:51 AM
  • 166 views

On biological markers and "subphenotypes" of autism

by Paul Whiteley in Questioning Answers

I don't want to keep you today. Just long enough to draw your attention to the paper by Jones and colleagues [1] regarding "ongoing efforts toward identification of early biological markers specific to subphenotypes of ASD [autism spectrum disorder]."The potential biomarkers in question this time around were the cytokines/chemokines - those various signalling molecules that seem to have more than a few connections to important processes like inflammation - and how their profile ("mid-gestat........ Read more »

  • June 10, 2016
  • 02:40 PM
  • 175 views

New tool brings personalized medicine closer

by Dr. Jekyll in Lunatic Laboratories

Scientists have developed a powerful tool for exploring and determining the inherent biological differences between individuals, which overcomes a major hurdle for personalized medicine.

... Read more »

Williams, E., Wu, Y., Jha, P., Dubuis, S., Blattmann, P., Argmann, C., Houten, S., Amariuta, T., Wolski, W., Zamboni, N.... (2016) Systems proteomics of liver mitochondria function. Science, 352(6291). DOI: 10.1126/science.aad0189  

  • June 10, 2016
  • 02:14 PM
  • 130 views

It can be a good thing for a therapist and client to disagree about the client's problems

by BPS Research Digest in BPS Research Digest

Rapport between a client and therapist is important for therapy to be successful, and part of that is agreeing about the aims of the exercise. You’d think this would include the therapist and client agreeing about the specific nature of the client’s psychological problems. In fact, a new study in Psychotherapy Research finds disagreement isn't harmful to therapy and can even be beneficial.Rolf Holmqvist and his colleagues recruited 846 therapy clients as they started a course of therapy at a........ Read more »

  • June 10, 2016
  • 01:51 PM
  • 147 views

Yellow fever virus in Africa: current situation and importance

by thelonevirologist in Virology Tidbits

Yellow haemorraghic fever (YF) is caused by Yellow Fever Virus (YFV), a prototype Flavivirus and as such as related to Japanese Encephalitis Virus (JEV), Dengue Virus (DENV) and Zika Virus (ZIKV). Similar to DENV and ZIKV, YFV is transmitted by Aedes agypti both in Africa and South America and clinical manifestations range from asymptomatic infections to multi organ failure and subsequent death.Here the current outbreak in Angola is discussed. ... Read more »

Wasserman S, Tambyah PA, & Lim PL. (2016) Yellow fever cases in Asia: primed for an epidemic. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. PMID: 27156836  

Monath, T. (2001) Yellow fever: an update. The Lancet Infectious Diseases, 1(1), 11-20. DOI: 10.1016/S1473-3099(01)00016-0  

Carrington CV, & Auguste AJ. (2013) Evolutionary and ecological factors underlying the tempo and distribution of yellow fever virus activity. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 198-210. PMID: 22981999  

Cathey, J., & Marr, J. (2014) Yellow fever, Asia and the East African slave trade. Transactions of the Royal Society of Tropical Medicine and Hygiene, 108(8), 519-519. DOI: 10.1093/trstmh/tru081  

Monath TP. (1999) Facing up to re-emergence of urban yellow fever. Lancet (London, England), 353(9164), 1541. PMID: 10334247  

Theiler M, & Anderson CR. (1975) The relative resistance of dengue-immune monkeys to yellow fever virus. The American journal of tropical medicine and hygiene, 24(1), 115-7. PMID: 1111351  

  • June 10, 2016
  • 11:50 AM
  • 165 views

Beetle Moms Make Anti-Aphrodisiac to Keep Dads Focused on Parenting

by Elizabeth Preston in Inkfish



"Not tonight, honey," says the female burying beetle, chewing up a mouthful of mouse carcass before spitting it into the mouth of a begging larva.

For the first few days of their babies' lives, burying beetles co-parent. They devote themselves to keeping their squirming larvae alive. That means mating and laying more eggs would be a waste of energy. And to make sure males get that message, females emit a pheromone that turns them off.

"It is quite surprising," says University of Ulm be... Read more »

  • June 10, 2016
  • 08:31 AM
  • 203 views

Decoding Faces from the Brain

by Neuroskeptic in Neuroskeptic_Discover

In a fascinating new paper, researchers Hongmi Lee and Brice A. Kuhl report that they can decode faces from neural activity. Armed with a brain scanner, they can reconstruct which face a participant has in mind. It's a cool technique that really seems to fit the description of 'mind reading' - although the method's accuracy is only modest.


Here's how they did it. Lee and Kuhl started out with a set of over 1000 color photos of different faces. During an fMRI scan, these images were shown to... Read more »

Lee H, & Kuhl BA. (2016) Reconstructing Perceived and Retrieved Faces from Activity Patterns in Lateral Parietal Cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(22), 6069-82. PMID: 27251627  

  • June 10, 2016
  • 06:14 AM
  • 209 views

BHD syndrome and thyroid conditions

by Joana Guedes in BHD Research Blog

Dong et al., (2016) have recently reported two BHD syndrome patients also affected with papillary thyroid cancer. Lesions were bilateral and multifocal and small lymph node metastases occurred. Due to the small number of patients in the study the authors are unsure whether thyroid cancer in BHD patients is susceptible to exhibiting bilaterally and lymph node metastasis. However, they suggest considering thyroidectomy and prophylactic lymph node dissection for thyroid cancer patients with BHD. Th........ Read more »

  • June 10, 2016
  • 03:07 AM
  • 181 views

Anti-NMDA-receptor encephalitis "mimicking an autistic regression"

by Paul Whiteley in Questioning Answers

Anti-NMDA-receptor encephalitis is not something that I ever envisaged talking about so much on this blog primarily concerned with autism research. Describing an often severe form of encephalitis where the body mounts an immune response against self ("the NR1 subunit of the NMDA receptor"), this condition is more readily associated with the symptoms of psychosis than anything specifically autism-related.But yet again (see here and see here) I'm talking about peer-reviewed research suggestin........ Read more »

Hacohen Y, Wright S, Gadian J, Vincent A, Lim M, Wassmer E, & Lin JP. (2016) N-methyl-d-aspartate (NMDA) receptor antibodies encephalitis mimicking an autistic regression. Developmental medicine and child neurology. PMID: 27255282  

  • June 9, 2016
  • 11:45 PM
  • 177 views

Multiple realizability of replicator dynamics

by Artem Kaznatcheev in Evolutionary Games Group

Abstraction is my favorite part of mathematics. I find a certain beauty in seeing structures without their implementations, or structures that are preserved across various implementations. And although it seems possible to reason through analogy without (explicit) abstraction, I would not enjoy being restricted in such a way. In biology and medicine, however, I often […]... Read more »

Taylor, P., & Jonker, L. (1978) Evolutionary stable strategies and game dynamics. Mathematical Biosciences, 40(1-2), 145-156. DOI: 10.1016/0025-5564(78)90077-9  

  • June 9, 2016
  • 04:13 PM
  • 172 views

Researchers watch skin cells 'walk' to wounds

by Dr. Jekyll in Lunatic Laboratories

New research is giving a whole new meaning to feeling your skin crawl. Skin cells typically spend their entire existence in one place on your body. But researchers have seen how the cells will alter the proteins holding them in place and move to repair a wound.

... Read more »

  • June 9, 2016
  • 11:21 AM
  • 90 views

Back to life – Resurrection plants and the future of food

by Alice Breda in la-Plumeria

Life on Earth was born in water. Then, about half a billion years ago, the first organisms stare colonizing lands that offered new spaces, less predators and, in time, abundant oxygen and nutrients. Still, the indissoluble bond that living organisms had with water remained, and in order to survive in this new environment plants and animals had to develop anatomical, physiological and behavioral adaptations to better obtain, manage and save water. Plant bodies, as well as ours, are mostly made of........ Read more »

Moore, J., Le, N., Brandt, W., Driouich, A., & Farrant, J. (2009) Towards a systems-based understanding of plant desiccation tolerance. Trends in Plant Science, 14(2), 110-117. DOI: 10.1016/j.tplants.2008.11.007  

  • June 9, 2016
  • 05:36 AM
  • 96 views

Parents who think failure is harmful to learning have children who think ability is fixed

by BPS Research Digest in BPS Research Digest

Children respond better to learning setbacks when they believe that ability and intelligence are malleable – that is, when they have what psychologists call a "growth mindset" rather than a "fixed mindset". This immediately raises the question of how to cultivate a growth mindset in children.So far, there's been a lot of attention on how to praise children (it's better to focus on their effort and strategies rather than their ability), but not much else. Surprisingly, parents' mindsets (growth........ Read more »

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