We discuss properties of type III bursts that change the sign of their drift rate from negative to positive and vice versa. Moreover, these bursts may change the sign of their drift rates more than once. These particular type III bursts were observed simultaneously by the radio telescopes UTR-2, URAN-2, [...]... Read more »
V. Melnik et al. (2015) Decameter type III bursts with changing frequency drift-rate signs . Solar Physics. info:/
'The times they are a changin'' said a Nobel prize winner and that's also a sentiment that seems true when it comes to chronic fatigue syndrome / myalgic encephalomyeltis (CFS/ME) too (see here for example).Anyone who has followed the tos-and-fros of the PACE trial - the one that suggested that CBT (cognitive behavioural therapy) and GET (graded exercise therapy) might provide some significant relief of symptoms associated with CFS/ME - will probably have heard the ........ Read more »
Geraghty KJ, & Esmail A. (2016) Chronic fatigue syndrome: is the biopsychosocial model responsible for patient dissatisfaction and harm?. The British journal of general practice : the journal of the Royal College of General Practitioners, 66(649), 437-8. PMID: 27481982
Bladder cancer is the seventh most common cancer in males worldwide. Every year, about 20,000 people in Japan are diagnosed with bladder cancer, of whom around 8,000--mostly men--succumb to the disease. Bladder cancers can be grouped into two types: non-muscle-invasive cancers, which have a five-year survival rate of 90 percent, and muscle-invasive cancers, which have poor prognoses.
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Matsumoto, R., Tsuda, M., Yoshida, K., Tanino, M., Kimura, T., Nishihara, H., Abe, T., Shinohara, N., Nonomura, K., & Tanaka, S. (2016) Aldo-keto reductase 1C1 induced by interleukin-1β mediates the invasive potential and drug resistance of metastatic bladder cancer cells. Scientific Reports, 34625. DOI: 10.1038/srep34625
How has changes in sea water chemistry and mass extinctions influenced the evolution and diversity of aragonite versus calcite marine skeletal groups through time..... Read more »
Hautmann, M. (2006) Shell mineralogical trends in epifaunal Mesozoic bivalves and their relationship to seawater chemistry and atmospheric carbon dioxide concentration. Facies, 52(3), 417-433. DOI: 10.1007/s10347-005-0029-x
PORTER, S. (2010) Calcite and aragonite seas and the de novo acquisition of carbonate skeletons. Geobiology, 8(4), 256-277. DOI: 10.1111/j.1472-4669.2010.00246.x
Zhuravlev, A., & Wood, R. (2009) Controls on carbonate skeletal mineralogy: Global CO2 evolution and mass extinctions. Geology, 37(12), 1123-1126. DOI: 10.1130/G30204A.1
Adolescents with persistent postconcussive symptoms experienced greater improvements in symptoms and quality of life after receiving a collaborative care treatment compared with adolescents who received the standard of care.... Read more »
McCarty CA, Zatzick D, Stein E, Wang J, Hilt R, Rivara FP, & Seattle Sports Concussion Research Collaborative. (2016) Collaborative Care for Adolescents With Persistent Postconcussive Symptoms: A Randomized Trial. Pediatrics. PMID: 27624513
Meta-analyses eh? You spend ages waiting for one and two come along in quick succession. Well today I'm posting about yet another meta-analysis of the peer-reviewed scientific literature suggesting that "excessive maternal BMI [body mass index] is associated with an increased ASD [autism spectrum disorder] risk in offspring." The review by Ying Wang et al follows hot on the heels of the meta-analysis by Li and colleagues  (see here for my take) but further looked a........ Read more »
Wang, Y., Tang, S., Xu, S., Weng, S., & Liu, Z. (2016) Maternal Body Mass Index and Risk of Autism Spectrum Disorders in Offspring: A Meta-analysis. Scientific Reports, 34248. DOI: 10.1038/srep34248
Social interactions are highly sought-after and rewarding in many animals... Even when social interactions involve only one of our senses, they are still rewarding. For example, we like looking at photos of our friends on Facebook, or hearing the voice of a faraway relative via telephone. It’s the same with other animals; not only is socialization rewarding and can be used as an incentive for learning, but just the sights, sounds, and even smells of others are also rewarding. Hernandez et ........ Read more »
Hernandez AM, Perez EC, Mulard H, Mathevon N, & Vignal C. (2016) Mate call as reward: Acoustic communication signals can acquire positive reinforcing values during adulthood in female zebra finches (Taeniopygia guttata). Journal of comparative psychology (Washington, D.C. : 1983), 130(1), 36-43. PMID: 26881942
Although it has already been known for some time that the brain does not remain rigid in its structure even in adulthood, scientists have recently made a surprising discovery. The brain is not only able to adapt to changing conditions in long-term processes, but it can do this every month.
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Barth, C., Steele, C., Mueller, K., Rekkas, V., Arélin, K., Pampel, A., Burmann, I., Kratzsch, J., Villringer, A., & Sacher, J. (2016) In-vivo Dynamics of the Human Hippocampus across the Menstrual Cycle. Scientific Reports, 32833. DOI: 10.1038/srep32833
In the previous two posts I’ve gone through the depressing exercise of exploring the misconstrued world-view that led the UK to leave the EU. The picture that emerges is not limited to the UK, but is a paradigm example of…Read more ›... Read more »
Nickerson, R. (1998) Confirmation bias: A ubiquitous phenomenon in many guises. Review of General Psychology, 2(2), 175-220. DOI: 10.1037//1089-2618.104.22.168
Lord, C., Ross, L., & Lepper, M. (1979) Biased assimilation and attitude polarization: The effects of prior theories on subsequently considered evidence. Journal of Personality and Social Psychology, 37(11), 2098-2109. DOI: 10.1037//0022-3522.214.171.1248
Corner, A., Whitmarsh, L., & Xenias, D. (2012) Uncertainty, scepticism and attitudes towards climate change: biased assimilation and attitude polarisation. Climatic Change, 114(3-4), 463-478. DOI: 10.1007/s10584-012-0424-6
Tauopathies are a group of neurodegenerative disorders, including Alzheimer's disease that are characterized by the deposition of aggregates of the tau protein inside brain cells. A new study reveals that the cutting of tau by an enzyme called caspase-2 may play a critical role in the disordered brain circuit function that occurs in these diseases.
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Zhao, X., Kotilinek, L., Smith, B., Hlynialuk, C., Zahs, K., Ramsden, M., Cleary, J., & Ashe, K. (2016) Caspase-2 cleavage of tau reversibly impairs memory. Nature Medicine. DOI: 10.1038/nm.4199
Where is the suprachiasmatic nucleus?
the suprachiasmatic nucleus is represented by a small green area within the hypothalamus (indicated by red arrow).
The suprachiasmatic nuclei are two small, paired nuclei that are found in the hypothalamus. Each suprachiasmatic nucleus only contains approximately 10,000 neurons. The nuclei rest on each side of the third ventricle, just above the optic chiasm. The location provides the rationale for........ Read more »
Colwell, C. (2011) Linking neural activity and molecular oscillations in the SCN. Nature Reviews Neuroscience, 12(10), 553-569. DOI: 10.1038/nrn3086
Impact loads in barefoot and shoe running... Read more »
Sinclair, J. (2016) The effects of barefoot and barefoot inspired footwear on tibiofemoral kinetics during running. Human Movement. DOI: 10.1515/humo-2016-0022
I'm not gonna dwell too much on the findings reported by Lee and colleagues  talking about how "toddlers who suffer from AD [atopic dermatitis] at the age younger than 3 years are at a higher risk of developing ADHD [attention-deficit hyperactivity disorder] and ASD [autism spectrum disorder] during later childhood" because science already seems to understand that there may be an important connection between early allergic disease and later offspring behavioural/........ Read more »
Lee CY, Chen MH, Jeng MJ, Hsu JW, Tsai SJ, Bai YM, Hung GY, Yen HJ, Chen TJ, & Su TP. (2016) Longitudinal association between early atopic dermatitis and subsequent attention-deficit or autistic disorder: A population-based case-control study. Medicine, 95(39). PMID: 27684861
High cholesterol might harm more than our cardiovascular systems. New research using animal models suggests that high cholesterol levels trigger mitochondrial oxidative stress on cartilage cells, causing them to die, and ultimately leading to the development of osteoarthritis.
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Farnaghi, S., Prasadam, I., Cai, G., Friis, T., Du, Z., Crawford, R., Mao, X., & Xiao, Y. (2016) Protective effects of mitochondria-targeted antioxidants and statins on cholesterol-induced osteoarthritis. The FASEB Journal. DOI: 10.1096/fj.201600600R
Bibliometric indicators represent much more than an indication of the visibility, relevance and impact of an article. A researcher’s entire career profile can be summarized in one or more numerical productivity and impact indicators of his research. However, citation metrics vary considerably according to the area of knowledge, the publication age, the type of document and the coverage of the database where citations were accrued. Is it possible to normalize them? Here we discuss the challenge........ Read more »
Ioannidis, J., Boyack, K., & Wouters, P. (2016) Citation Metrics: A Primer on How (Not) to Normalize. PLOS Biology, 14(9). DOI: 10.1371/journal.pbio.1002542
BLOWFIELD, M., & FRYNAS, J. (2005) Editorial Setting new agendas: critical perspectives on Corporate Social Responsibility in the developing world. International Affairs, 81(3), 499-513. DOI: 10.1111/j.1468-2346.2005.00465.x
Hutchins, B., Yuan, X., Anderson, J., & Santangelo, G. (2016) Relative Citation Ratio (RCR): A New Metric That Uses Citation Rates to Measure Influence at the Article Level. PLOS Biology, 14(9). DOI: 10.1371/journal.pbio.1002541
Neuroscience medicine clinicians encounter patients every day who have both a mental and substance use disorder.This co-occurrence, or comorbidity, complicates diagnosis, treatment and outcome.The exact mechanism for this comorbidity issue is unclear.A recent study out of Washington University in St. Louis and King's College London provides some insight into this comorbidity issue.They examined participants in the Study of Addiction: Genetics and Environment (SAGE). These subjects provided genet........ Read more »
Carey CE, Agrawal A, Bucholz KK, Hartz SM, Lynskey MT, Nelson EC, Bierut LJ, & Bogdan R. (2016) Associations between Polygenic Risk for Psychiatric Disorders and Substance Involvement. Frontiers in genetics, 149. PMID: 27574527
by Piter Kehoma Boll I wonder how many people can say they have a bacterium that reminds them of their childhood. Well, at least I can say that I have. When I was a boy and started to know about … Continue reading →... Read more »
Lipman, C. (1941) The Successful Revival of Nostoc commune from a Herbarium Specimen Eighty- Seven Years Old. Bulletin of the Torrey Botanical Club, 68(9), 664. DOI: 10.2307/2481755
Tamaru, Y., Takani, Y., Yoshida, T., & Sakamoto, T. (2005) Crucial Role of Extracellular Polysaccharides in Desiccation and Freezing Tolerance in the Terrestrial Cyanobacterium Nostoc commune. Applied and Environmental Microbiology, 71(11), 7327-7333. DOI: 10.1128/AEM.71.11.7327-7333.2005
Forgetting Earth Dementia. Few words inspire greater fear in those of us who value (quasi-?) independent thought. The term ‘dementia’ encompasses various brain disorders that all share some scary traits: general decline in cognitive function, decreased ability to speak, and in later stages, being unable to take care of oneself. Unfortunately, as human lifespan increases […]... Read more »
Killin LO, Starr JM, Shiue IJ, & Russ TC. (2016) Environmental risk factors for dementia: a systematic review. BMC geriatrics, 16(1), 175. PMID: 27729011
Parihar VK, Allen BD, Caressi C, Kwok S, Chu E, Tran KK, Chmielewski NN, Giedzinski E, Acharya MM, Britten RA.... (2016) Cosmic radiation exposure and persistent cognitive dysfunction. Scientific reports, 34774. PMID: 27721383
'Thick and fast' is probably the best way that I can describe the flurry of peer-reviewed scientific papers recently appearing (see here and see here for examples) talking about how chronic fatigue syndrome (CFS) (also linked to the diagnosis of myalgic encephalomyelitis, ME) might have some important biological processes attached to it.Now we can add the findings reported by Federica Ciregia and colleagues  (open-access) to the list and their observations that "the identification of bio........ Read more »
Ciregia F, Kollipara L, Giusti L, Zahedi RP, Giacomelli C, Mazzoni MR, Giannaccini G, Scarpellini P, Urbani A, Sickmann A.... (2016) Bottom-up proteomics suggests an association between differential expression of mitochondrial proteins and chronic fatigue syndrome. Translational psychiatry, 6(9). PMID: 27676445
Researchers from the Studies and Research Group in Health Services Administration and Nursing Management from The Universidade Federal de São Paulo (UNIFESP) have developed studies to improve the practice of sustainable actions from an environmental point of view in hospitals. A recent doctoral thesis study carried out by researcher of the UNIFESP and member of the group, analyzed the sustainable actions taken by the nursing staff of an Intensive Care Unit (ICU) during the medication process an........ Read more »
Patricia de Oliveira Furukawa,, Isabel Cristina Kowal Olm Cunha,, Mavilde da Luz Gonçalves Pedreira,, & Patricia Beryl Marck. (2016) Sustentabilidade ambiental nos processos de medicação realizados na assistência de enfermagem hospitalar. Acta Paulista de Enfermagem, 29(3), 316-324. DOI: http://dx.org/10.1590/1982-0194201600044
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