Post List

  • June 11, 2015
  • 08:19 PM
  • 30 views

Pre-Frontal Brain Cortex Size Linked To Moral Reasoning

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Dr. rer. nat. Kristin Prehn, Dipl.-Psych. Charité Universitätsmedizin Berlin Department of Neurology & NeuroCure Clinical Research Cente Berlin Germany MedicalResearch: What is the background for this study? What are the main findings? Dr. Prehn: The study is … Continue reading →
The post Pre-Frontal Brain Cortex Size Linked To Moral Reasoning appeared first on MedicalResearch.com Medic........ Read more »

Dr. rer. nat. Kristin Prehn, Dipl.-Psych., Charité Universitätsmedizin Berlin, Department of Neurology , & Berlin Germany. (2015) Pre-Frontal Brain Cortex Size Linked To Moral Reasoning. MedicalResearch.com. info:/

  • June 11, 2015
  • 06:15 PM
  • 40 views

Oncotype DX Breast Cancer Assay Quickly Adopted Under Medicare Guidelines

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Michaela Dinan, Ph.D. Duke Clinical Research Institute and Duke Cancer Institute Department of Medicine Duke University School of Medicine Durham, North Carolina Medical Research: What is the background for this study? What are the main findings? Response: … Continue reading →
The post Oncotype DX Breast Cancer Assay Quickly Adopted Under Medicare Guidelines appeared first on MedicalResearch......... Read more »

Michaela Dinan, Ph.D. Duke Clinical Research Institute and Duke Cancer Institute, Department of Medicine, Duke University School of Medicine, & Durham, North Carolina. (2015) Oncotype DX Breast Cancer Assay Quickly Adopted Under Medicare Guidelines. MedicalResearch.com. info:/

  • June 11, 2015
  • 05:41 PM
  • 42 views

Functional Status Is Important Predictor of Hospital Readmission

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Jeffrey C. Schneider, M.D. Medical Director, Trauma, Burn & Orthopedic Program Assistant Professor, Dept. of Physical Medicine and Rehabilitation Harvard Medical School Spaulding Rehabilitation Hospital Boston, MA 02129 Medical Research: What is the background for this study? … Continue reading →
The post Functional Status Is Important Predictor of Hospital Readmission appeared first on M........ Read more »

Jeffrey C. Schneider, M.D., Medical Director, Trauma, Burn , Assistant Professor, Dept. of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, & Boston, MA 02129. (2015) Functional Status Is Important Predictor of Hospital Readmission. MedicalResearch.com. info:/

  • June 11, 2015
  • 05:32 PM
  • 36 views

New Borrelia Tick-Borne Disease Confirmed in Series of 51 Patients

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Dr. Philip Molloy, MD Imugen Medical Director Medical Research: What is the background for this study? What are the main findings? Response: There is a newly described tick-borne infection in the US, first case published in NEJM … Continue reading →
The post New Borrelia Tick-Borne Disease Confirmed in Series of 51 Patients appeared first on MedicalResearch.com Medical Research Interviews and........ Read more »

Dr. Philip Molloy, MD, & Imugen Medical Director. (2015) New Borrelia Tick-Borne Disease Confirmed in Series of 51 Patients. MedicalResearch.com. info:/

  • June 11, 2015
  • 05:21 PM
  • 64 views

Lump Sum Payments To Long-term Care Hospitals May Have Created Incentive To Discharge Patients

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Yan S. Kim, MD PhD Delivery Science Fellow Division of Research Kaiser Permanente Northern California Oakland, CA 94612 Medical Research: What is the background for this study? What are the main findings? Dr. Kim: Long-term care hospitals … Continue reading →
The post Lump Sum Payments To Long-term Care Hospitals May Have Created Incentive To Discharge Patients appeared first on MedicalResear........ Read more »

MedicalResearch.com Interview with: Yan S. Kim, MD PhD, Delivery Science Fellow Division of Research, Kaiser Permanente Northern California, & Oakland, CA 94612. (2015) Lump Sum Payment To Long-term Care Hospitals May Have Created Incentive To Discharge Patients. MedicalResearch.com. info:/

  • June 11, 2015
  • 04:31 PM
  • 66 views

AKAP4 Is a Promising Blood Biomarker For Early Detection of Lung Cancer

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Qihong Huang, M.D., Ph.D. Associate professor in the Tumor Microenvironment and Metastasis Program The Wistar Institute Medical Research: What is the background for this study? What are the main findings? Dr. Huang: Lung cancer is the leading … Continue reading →
The post AKAP4 Is a Promising Blood Biomarker For Early Detection of Lung Cancer appeared first on MedicalResearch.com Medical Rese........ Read more »

Qihong Huang, M.D., Ph.D., Associate professor in the Tumor Microenvironment and Metastasis Program, & The Wistar Institute. (2015) AKAP4 Is a Promising Blood Biomarker For Early Detection of Lung Cancer. MedicalResearch.com. info:/

  • June 11, 2015
  • 04:16 PM
  • 79 views

Noninvasive Prenatal Testing May Detect Maternal Cancer

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Prof. Joris Vermeesch Hoofd Moleculaire Cytogenetica Coordinator Genomics Core University of Leuven, University Hospitals Leuven, Belgium Medical Research: What is the background for this study? What are the main findings? Dr. Vermeesch: We developed a novel analysis … Continue reading →
The post Noninvasive Prenatal Testing May Detect Maternal Cancer appeared first on MedicalResearch.com Med........ Read more »

Prof. Joris Vermeesch, Hoofd Moleculaire Cytogenetica, & Coordinator Genomics Core. (2015) Noninvasive Prenatal Testing May Detect Maternal Cancer. MedicalResearch.com. info:/

  • June 11, 2015
  • 03:59 PM
  • 110 views

The curious case of Neisseria and the seven-carbon sugar

by Betty Zou in Eat, Read, Science

Neisseria gonorrhoeae releases a seven carbon sugar that activates HIV gene expression and functions as a pathogen associated molecular pattern. Here's the story of how it was discovered and why it could be helping Neisseria evade our immune system.... Read more »

Malott, R., Keller, B., Gaudet, R., McCaw, S., Lai, C., Dobson-Belaire, W., Hobbs, J., St. Michael, F., Cox, A., Moraes, T.... (2013) Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression. Proceedings of the National Academy of Sciences, 110(25), 10234-10239. DOI: 10.1073/pnas.1303738110  

Ryan G. Gaudet,, Anna Sintsova,, Carolyn M. Buckwalter,, Nelly Leung,, Alan Cochrane,, Jianjun Li,, Andrew D. Cox,, Jason Moffat,, & Scott D. Gray-Owen. (2015) Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity . Science, 1251-1255. info:/10.1126/science.aaa4921

  • June 11, 2015
  • 03:12 PM
  • 104 views

Milk proteins may protect against cardiovascular disease

by Dr. Jekyll in Lunatic Laboratories

The Maillard reaction is a chemical reaction between amino acids and reducing sugars that results in browned foods like seared steaks and toasted bread. When proteins and sugars are mixed together and heated, new chemical compounds are formed. Some are responsible for new flavors and some, according to a new study, may protect us against cardiovascular disease.... Read more »

  • June 11, 2015
  • 09:35 AM
  • 124 views

What’s the Answer? (pan-genome graphs)

by Mary in OpenHelix

This weeks highlighted discussion is the problem of pan-genome graphs, which are ways to represent the variation we find in genomes instead of a linear reference sequence view. I was really struggling with these concepts until I heard a talk at the #TRICON meeting recently. David Haussler had some really helpful visuals. I don’t have […]... Read more »

Benedict Paten, Adam Novak, & David Haussler. (2014) Mapping to a Reference Genome Structure. arXiv.org. arXiv: 1404.5010v1

Nguyen, N., Hickey, G., Zerbino, D., Raney, B., Earl, D., Armstrong, J., Kent, W., Haussler, D., & Paten, B. (2015) Building a Pan-Genome Reference for a Population. Journal of Computational Biology, 22(5), 387-401. DOI: 10.1089/cmb.2014.0146  

  • June 11, 2015
  • 08:58 AM
  • 117 views

Active hematopoietic sites in Drosophila Adult

by LolitikaMandal in the Node

Studies in the last decade have established Drosophila as the best invertebrate model to study hematopoiesis. Blood cell development in the fruitfly has been shown to have similarities to that of vertebrates both at the level of its origins and important signaling molecules necessary for their formation and differentiation (Evans et al., 2003). It was believed […]... Read more »

  • June 11, 2015
  • 08:00 AM
  • 92 views

The catch-22 of recording from identified cell populations

by Michael Patterson in ...And You Will Know Me By The Trail of Papers

Recording from individual cells in genetically identified populations is the hottest technique in systems neuroscience right now (I am, of course, totally biased since that's what I'm trying to do). To record from identified populations, you first choose a mouse line that expresses Cre driven by a cell-specific marker like D1R. Then you transduce those cells with floxed ChR2 or GCaMP so you can ... Read more »

Betley, J., Xu, S., Cao, Z., Gong, R., Magnus, C., Yu, Y., & Sternson, S. (2015) Neurons for hunger and thirst transmit a negative-valence teaching signal. Nature, 521(7551), 180-185. DOI: 10.1038/nature14416  

Jennings, J., Ung, R., Resendez, S., Stamatakis, A., Taylor, J., Huang, J., Veleta, K., Kantak, P., Aita, M., Shilling-Scrivo, K.... (2015) Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors. Cell, 160(3), 516-527. DOI: 10.1016/j.cell.2014.12.026  

  • June 11, 2015
  • 05:11 AM
  • 142 views

Higher vitamin D = reduced risk of depression?

by Paul Whiteley in Questioning Answers

"These results support the hypothesis that higher serum 25(OH)D concentrations protect against depression even after adjustment for a large number of sociodemographic, lifestyle and metabolic factors."That was the conclusion reached by Tuija Jääskeläinen and colleagues [1] who analysed data from several thousands of people (men and women aged between 30 -79 years old) included as part of the Finnish Health 2000 survey. Alongside assaying for serum levels of 25(OH)D - 25-hydroxy vitamin D........ Read more »

Jääskeläinen T, Knekt P, Suvisaari J, Männistö S, Partonen T, Sääksjärvi K, Kaartinen NE, Kanerva N, & Lindfors O. (2015) Higher serum 25-hydroxyvitamin D concentrations are related to a reduced risk of depression. The British journal of nutrition, 113(9), 1418-26. PMID: 25989997  

  • June 10, 2015
  • 08:37 PM
  • 71 views

Treatment With TNF-α inhibitors Raises Short Term Risk Of Infection in Inflammatory Bowel Disease

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Nynne Nyboe Andersen, MD, PhD student Department of Epidemiology Research Statens Serum Institut Copenhagen, Denmark Medical Research: What is the background for this study? What are the main findings? Dr. Andersen: The use of TNF-α inhibitors, including … Continue reading →
The post Treatment With TNF-α inhibitors Raises Short Term Risk Of Infection in Inflammatory Bowel Disease appeared f........ Read more »

Nynne Nyboe Andersen, MD, PhD student Department of Epidemiology Research, Statens Serum Institut, & Copenhagen, Denmark. (2015) Treatment With TNF-α inhibitors Raises Short Term Risk Of Infection in Inflammatory Bowel Disease. MedicalResearch.com. info:/

  • June 10, 2015
  • 08:10 PM
  • 70 views

Lack of Random Allocation of Participants May Make Observational Research Misleading

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Andrew Grey, MD Department of Medicine University of Auckland Auckland, New Zealand Medical Research: What is the background for this study? What are the main findings? Dr. Grey: Observational research is commonly conducted and often published in prominent medical … Continue reading →
The post Lack of Random Allocation of Participants May Make Observational Research Misleading appeared firs........ Read more »

Andrew Grey, MD, Department of Medicine, University of Auckland, & Auckland, New Zealand. (2015) Lack of Random Allocation of Participants May Make Observational Studies Misleading. MedicalResearch.com. info:/

  • June 10, 2015
  • 07:21 PM
  • 97 views

Most Patients With Atrial Fibrillation Are Symptomatic and Have Impaired Quality of Life

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: James V. Freeman MD, MPH, MS Yale University School of Medicine New Haven, CT Medical Research: What is the background for this study? What are the main findings? Dr. Freeman: Atrial fibrillation (AF) substantially increases the risk … Continue reading →
The post Most Patients With Atrial Fibrillation Are Symptomatic and Have Impaired Quality of Life appeared first on MedicalResearch.com Medi........ Read more »

James V. Freeman MD, MPH, MS, Yale University School of Medicine, & New Haven, CT. (2015) Most Patients With Atrial Fibrillation Symptomatic and Have Impaired Quality of Life. MedicalResearch.com. info:/

  • June 10, 2015
  • 06:15 PM
  • 113 views

New drug can clear all psoriasis symptoms

by Dr. Jekyll in Lunatic Laboratories

Good news for anyone who has psoriasis, a University of Manchester led trial of a new drug has resulted in 40 percent of people showing a complete clearance of psoriatic plaques after 12 weeks of treatment and over 90 percent showing improvement. The research tested 2,500 people with psoriasis. Half were given a new drug – ixekizumab – either once every two or four weeks. The other half were given a placebo or a widely used drug for psoriasis called etanercept.... Read more »

Prof Christopher E M, Griffiths, MD, Prof Kristian Reich, MD, Prof Mark Lebwohl, MD, Prof Peter van de Kerkhof, MD, Prof Carle Paul, MD, Alan Menter, MD, Gregory S Cameron, PhD, Janelle Erickson, PhD, Lu Zhang, MS.... (2015) Comparison of ixekizumab with etanercept or placebo in moderate-to-severe psoriasis (UNCOVER-2 and UNCOVER-3): results from two phase 3 randomised trials . Lancet. DOI: http://dx.org/10.1016/S0140-6736(15)60125-8  

  • June 10, 2015
  • 05:44 PM
  • 129 views

First functional, synthetic immune organ with controllable antibodies created by engineers

by Dr. Jekyll in Lunatic Laboratories

Cornell University engineers have created a functional, synthetic immune organ that produces antibodies and can be controlled in the lab, completely separate from a living organism. The engineered organ has implications for everything from rapid production of immune therapies to new frontiers in cancer or infectious disease research.... Read more »

Purwada, A., Jaiswal, M., Ahn, H., Nojima, T., Kitamura, D., Gaharwar, A., Cerchietti, L., & Singh, A. (2015) Ex vivo Engineered Immune Organoids for Controlled Germinal Center Reactions. Biomaterials. DOI: 10.1016/j.biomaterials.2015.06.002  

  • June 10, 2015
  • 05:12 PM
  • 58 views

Early Autism Intervention Produces Long Term Benefits

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Annette Estes, Ph.D. Research Associate Professor of Speech and Hearing Sciences Adjunct Research Associate Professor of Psychology Director, University of Washington Autism Center Susan & Richard Fade Endowed Chair Center on Human Development and Disability University of … Continue reading →
The post Early Autism Intervention Produces Long Term Benefits appeared first on MedicalResearch......... Read more »

MedicalResearch.com Interview with: Annette Estes, Ph.D., Research Associate Professor of Speech and Hearing Sciences, Adjunct Research Associate Professor of Psychology, Director, University of Washington Autism Center, Susan , Center on Human Development and Disability, & University of Washington. (2015) Early Autism Intervention Produces Long Term Benefits . MedicalResearch.com. info:/

  • June 10, 2015
  • 04:56 PM
  • 70 views

Social Support From Friends and Family Linked To Lower Mortality

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Katie Becofsky Ph.D. Weight Control and Diabetes Research Center The Miriam Hospital Providence, RI Medical Research: What is the background for this study? What are the main findings? Dr. Becofsky: Previous research has provided clear evidence of … Continue reading →
The post Social Support From Friends and Family Linked To Lower Mortality appeared first on MedicalResearch.com Medical Resear........ Read more »

Katie Becofsky Ph.D., Weight Control and Diabetes Research Center, The Miriam Hospital, & Providence, RI. (2015) Social Support From Friends and Family Linked To Lower Mortality. MedicalResearch.com. info:/

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