Post List

  • September 27, 2014
  • 08:03 PM
  • 131 views

How to Look for Pine Marten

by Denise O'Meara in Denise O'Meara

The pine marten (Martes martes) is one of Ireland’s most beautiful but elusive mammals. It is notoriously difficult to see as it tends to be mostly nocturnal, and is a naturally shy animal. It is about the size of a cat, and in Irish it is actually called the tree cat (cat crainn). The species historically suffered massive population declines due to forest removal in the 16th Century and pine marten were also trapped and killed for their fur, which was worn by the nobility across Europe. I........ Read more »

  • September 27, 2014
  • 02:18 PM
  • 148 views

Sometimes choices are not thought out

by Janet Kwasniak in Neuro-patch

In some competitive situations animals can produce random behavior rather than behavior based on prior experience. The anterior cingulate cortex is where strategies based on models of reality and history are generated; switching to random behavior is done by inputs to this part of the brain from the locus coeruleus. This was reported in a […]... Read more »

  • September 27, 2014
  • 01:29 PM
  • 179 views

Are Black Holes just in Our Imagination?!

by Gabriel in Lunatic Laboratories

Black holes, physicists have been fighting over them forever, heck there is even a book entitled the black hole war! (which I do recommend for anyone interested) It’s no real surprise since they are the ultimate unknown – the blackest and most dense objects in the universe that do not even let light escape. And as if they weren't bizarre enough to begin with, now add this to the mix: they don’t exist.... Read more »

Laura Mersini-Houghton, Harald P. Pfeiffer. (2014) Back-reaction of the Hawking radiation flux on a gravitationally collapsing star II: Fireworks instead of firewalls . Physics Letters B. info:/arXiv:1409.1837

  • September 27, 2014
  • 08:37 AM
  • 162 views

The Memory Fades, The Emotion Remains

by Neuroskeptic in Neuroskeptic_Discover

People with Alzheimer’s disease can experience severe memory impairments.However, according to a new study, the emotions associated with events can persist long after the events themselves have been forgotten: Feelings Without Memory in Alzheimer Disease In their paper, the researchers, University of Iowa neurologists Edmarie Guzman-Velez and colleagues, showed volunteers a series of emotional video […]The post The Memory Fades, The Emotion Remains appeared first on Neuroskeptic.... Read more »

Guzmán-Vélez E, Feinstein JS, & Tranel D. (2014) Feelings without memory in Alzheimer disease. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 27(3), 117-29. PMID: 25237742  

  • September 27, 2014
  • 03:50 AM
  • 158 views

Yes, people with autism do have headaches

by Paul Whiteley in Questioning Answers

I don't mean to be haughty but a sentence included in the paper by Victorio [1] led to the title of today's very quick post. Based on a chart review of patients diagnosed with an autism spectrum disorder (ASD) attending a neurology clinic, the author concluded that "ASD patients, despite being known to have indifference to pain, can experience headaches".Pain is something which has cropped up quite a bit in the autism research arena and has appeared more than once on this blog (see here and see ........ Read more »

  • September 26, 2014
  • 02:15 PM
  • 174 views

“GMO” Foods (Once Again) Proven Safe

by Gabriel in Lunatic Laboratories

GMO, I shudder every time I hear someone talk about the “dangers”. It’s one of the new buzzwords that doesn’t actually mean anything, but still manages to scare people. Well a new scientific review reports that the performance and health of food-producing animals consuming genetically engineered feed, first introduced 18 years ago, has been comparable to that of animals consuming non-GE feed. Not that this will stop people from spreading fear, but it’s a start.... Read more »

  • September 26, 2014
  • 10:30 AM
  • 158 views

Walking Really Is Just Falling and Catching Yourself

by Elizabeth Preston in Inkfish

The flailing of a gymnast who’s missed a step on the balance beam might not be far off from what the rest of us experience every day. Each step we take is really a tiny fall, a mathematical model suggests. The random-looking variation in our footfalls is actually a series of corrections. Our strides are […]The post Walking Really Is Just Falling and Catching Yourself appeared first on Inkfish.... Read more »

  • September 26, 2014
  • 08:14 AM
  • 157 views

Anthropomorphic Neuroscience Driven by Researchers with Large TPJs

by The Neurocritic in The Neurocritic

For immediate release — SEPTEMBER 26, 2014Research from the UCL lab of Professor Geraint Rees has proven that the recent craze for suggesting that rats have “regrets” or show “disappointment” is solely due to the size of the left temporal-parietal junction (TPJ) in the human authors of those papers (Cullen et al., 2014). This startling breakthrough was part of a larger effort to associate every known personality trait, political attitude, and individual difference with the size of a un........ Read more »

  • September 26, 2014
  • 08:00 AM
  • 146 views

Breaking Research: Fruit flies provide insights into metabolism and how we age

by Bethany Christmann in Fly on the Wall

Why do we age? It’s more than just a philosophical question; it’s a puzzle that has frustrated scientists for decades. Currently, the most accepted hypothesis is that aging is the result of accumulated damage to our cells during our lifetime. “Accumulated damage” encompasses a variety of things that can go wrong, including DNA mutations, problems […]... Read more »

  • September 26, 2014
  • 07:02 AM
  • 103 views

Would you prefer a smaller government? Actually, no you would not. 

by Rita Handrich in The Jury Room

For a number of years now, we have been asking our mock jurors what role they think government should play in our society and giving them a number of options among which to choose. Most of them say government should play a smaller role and we certainly have all heard the media messages that tell us […]

Related posts:
“Just about always” and “Never” responses to trusting the federal government
Men prefer boxes and women prefer ellipses?
You might be a conservative if…you p........ Read more »

  • September 26, 2014
  • 05:32 AM
  • 129 views

Schizophrenia after child and adolescent psychiatric disorders

by Paul Whiteley in Questioning Answers

More of a 'bring to your attention' post today, as I bring to your attention(!) the paper by Cecilie Frejstrup Maibing and colleagues [1] who concluded: "The risk of being diagnosed with schizophrenia spectrum disorders [SSD] after a child and adolescent psychiatric disorder was significantly increased particularly in the short term but also in the long-term period"."I coulda been a contender"The findings were based on an analysis of one of those very informative Scandinavian........ Read more »

  • September 26, 2014
  • 02:53 AM
  • 125 views

Telomere shortening may cause genetic anticipation in VHL syndrome

by Lizzie Perdeaux in BHD Research Blog

Genetic anticipation describes the situation where younger generations of a family with a genetic disease develop symptoms at a younger age, develop more severe symptoms, or both. A study earlier this year showed that there is evidence of genetic anticipation … Continue reading →... Read more »

  • September 25, 2014
  • 11:34 AM
  • 156 views

September 25, 2014

by Erin Campbell in HighMag Blog

While taking an awesome cell biology course in college, I was coming to terms with my mother’s recent ovarian cancer diagnosis. The scientist in my head couldn’t shake the curiosity about how my mother’s cells could have betrayed her so royally. This intersection of basic cell biology and cancer kick-started my interest in cell biology research. Today’s image is from a paper showing a role for the ARF tumor suppressor in maintaining chromosomal stability. THIS paper is one of the mil........ Read more »

  • September 25, 2014
  • 10:37 AM
  • 175 views

A New Discovery in the Treatment of Autoimmunity and Chronic Inflammation

by Gabriel in Lunatic Laboratories

Lupus, Type 1 diabetes, and multiple sclerosis are all diseases brought on by autoimmunity — the bodies inability to tell itself apart from foreign invaders. Finding a cure, or even a suitable treatment has been to put it gently a long, painful road, with little to show for it. On the forefront of the war against the body betrayal is immunosuppressants, which with them carry their own set of side effects and in most cases only off mild to moderate relief of symptoms. But that is all changing a........ Read more »

Dubiella C, Cui H, Gersch M, Brouwer AJ, Sieber SA, Krüger A, Liskamp RM, & Groll M. (2014) Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site. Angewandte Chemie (International ed. in English). PMID: 25244435  

  • September 25, 2014
  • 09:46 AM
  • 145 views

What’s the Answer? (domain and lollipop mutation diagrams)

by Mary in OpenHelix

Biostars is a site for asking, answering and discussing bioinformatics questions and issues. We are members of the community and find it very useful. Often questions and answers arise at Biostars that are germane to our readers (end users of genomics resources). Every Thursday we will be highlighting one of those items or discussions here […]... Read more »

Gao J., U. Dogrusoz, G. Dresdner, B. Gross, S. O. Sumer, Y. Sun, A. Jacobsen, R. Sinha, E. Larsson, & E. Cerami. (2013) Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal. Science Signaling, 6(269). DOI: http://dx.doi.org/10.1126/scisignal.2004088  

  • September 25, 2014
  • 05:10 AM
  • 167 views

Temporal trends in US autism prevalence: mainly real increase

by Paul Whiteley in Questioning Answers

"Diagnosed autism prevalence has risen dramatically in the U.S over the last several decades and continued to trend upward as of birth year 2005. The increase is mainly real and has occurred mostly since the late 1980s"."They call me Cha Cha because I'm the best dancer at St. Bernadette's"That was the conclusion reached in the paper by Cynthia Nevison [1] (open-access) following her analysis of temporal trends in autism diagnosis for birth years between 1970 and 2005. Based on an analysis o........ Read more »

  • September 25, 2014
  • 03:00 AM
  • 66 views

How do male scientists balance the demands of work and family?

by BPS Research Digest in BPS Research Digest

Academia remains heavily gendered, thanks in part to historical stereotypes that assert men are suited to solving complex problems and ready to put "great works" over other concerns such as community or family. Psychology and sociology have shown how this disadvantages women working in these fields, particularly if they wish to have children.A new study led by Sarah Damaske of Pennsylvania State University takes a different approach, looking at what this world is like for men. From the 73 male s........ Read more »

  • September 24, 2014
  • 07:27 PM
  • 132 views

Coronavirus PLpro, PLP2, and N: taking a STING out of antiviral signalling

by thelonevirologist in Virology Tidbits

The antiviral response following the infection of cells with positive RNA viruses involves the expression of genes encoding Interferon-α and -β (IFN-α /-β), both of which induce the expression of a number of Interferon stimulated genes (ISGs) in a an autocrine and paracrine manner. The activation of the expression of IFN-α and -β itself however depends on a cytoplasmic signaling pathway which involves the recognition of viral ssRNA and dsRNA intermediates by cell........ Read more »

Cornelissen T, Haddad D, Wauters F, Van Humbeeck C, Mandemakers W, Koentjoro B, Sue C, Gevaert K, De Strooper B, Verstreken P.... (2014) The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy. Human molecular genetics, 23(19), 5227-42. PMID: 24852371  

Oh JE, & Lee HK. (2014) Pattern recognition receptors and autophagy. Frontiers in immunology, 300. PMID: 25009542  

Ablasser A, & Hornung V. (2013) DNA sensing unchained. Cell research, 23(5), 585-7. PMID: 23419517  

van Kasteren PB, Bailey-Elkin BA, James TW, Ninaber DK, Beugeling C, Khajehpour M, Snijder EJ, Mark BL, & Kikkert M. (2013) Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells. Proceedings of the National Academy of Sciences of the United States of America, 110(9). PMID: 23401522  

Saitoh T, Fujita N, Hayashi T, Takahara K, Satoh T, Lee H, Matsunaga K, Kageyama S, Omori H, Noda T.... (2009) Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response. Proceedings of the National Academy of Sciences of the United States of America, 106(49), 20842-6. PMID: 19926846  

  • September 24, 2014
  • 03:54 PM
  • 129 views

A new Medicine may help Lupus Sufferers

by Gabriel in Lunatic Laboratories

Lupus, a particularly bad hell on earth for people suffering from it. Lupus is caused by autoimmunity, in where the body attacks itself. I have a special place in my heart for people suffering from the disease because my Uncle suffered from it. There is no cure and only moderately effective treatments for the disorder, which causes, in some cases, the most excruciating pain you will ever feel. Thankfully new findings by a biomedical engineering team raise hope for a new class of drugs to treat l........ Read more »

  • September 24, 2014
  • 12:48 PM
  • 98 views

Towards a synthetic embryo

by Aryeh Warmflash in the Node

Waddington, whose writings on the epigenetic landscape continue to influence developmental biology to this day, called the developing embryo “the most intriguing object that nature has to offer”(Waddington, 1966). The mechanisms of pattern formation and morphogenesis have fascinated biologists for centuries. One question that is difficult to answer is what are the minimal requirements for […]... Read more »

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