Immigrants are more often than natives diagnosed with schizophrenia. Afro-Carribeans in England, Inuits in Denmark and Moroccans in the Netherlands are among the most likely to become schizophrenic, according to a Dutch newspaper article. New research however has indicated that standardized test may overdiagnose immigrants due to cultural misinterpretation.... Read more »
Zandi T, Havenaar JM, Laan W, Kahn RS, & van den Brink W. (2011) Predictive validity of a culturally informed diagnosis of schizophrenia: a 30 month follow-up study with first episode psychosis. Schizophrenia research, 133(1-3), 29-35. PMID: 22019074
Zandi T, Havenaar JM, Smits M, Limburg-Okken AG, van Es H, Cahn W, Algra A, Kahn RS, & van den Brink W. (2010) First contact incidence of psychotic disorders among native Dutch and Moroccan immigrants in the Netherlands: influence of diagnostic bias. Schizophrenia research, 119(1-3), 27-33. PMID: 20332065
by Rita Handrich in The Jury Room
When your evidence is weak, how can you be more persuasive? Precision. Observers want to see certain things to have confidence in what you are saying. The more precise you are, the more likely the observer is to see you as knowledgeable and accurate (even when negotiating for salary!). So what does the observer look […]
Simple Jury Persuasion: Can walking to the jury room make jurors forget your evidence?
Simple Jury Persuasion: Hearsay evidence & the expert witness
Si........ Read more »
Jerez-Fernandez A, Angulo AN, & Oppenheimer DM. (2014) Show me the numbers: precision as a cue to others' confidence. Psychological Science, 25(2), 633-5. PMID: 24317423
Cross-section of the engineered tissue showing cartilage (red) filling in between and around the bundles of polymer fibers (white). Credit: Courtesy of Charles Gersbach and Farshid Guilak Duke UniversityBy combining a synthetic scaffolding material with gene delivery techniques, researchers at Duke University are getting closer to being able to generate replacement cartilage where it's needed in the body.Performing tissue repair with stem cells typically requires applying copious amounts of ........ Read more »
Brunger, J.M., Huynh, N.P.T., Guenther, C.M., Perez-Pinera, P., Moutos, F.T., Sanchez-Adams, J., Gersbach C.A., and Guilak F. (2014) Scaffold-mediated lentiviral transduction for functional tissue engineering of cartilage. PNAS Plus. DOI: 10.1073/pnas.1321744111
The paper for this week is"Hyperpolarization without persistent radical for in vivo real-time metabolic imaging"byEichhorn, Takado, Salameh, Capozzi, Cheng, Hyacinthe, Mishkovsky, Roussel and CommentPNAS 2013 110 18064http://www.ncbi.nlm.nih.gov/pubmed/24145405http://www.pnas.org/content/110/45/18064.longThere is a lot going on in this short and well-written paper. I highly recommend that you read it yourself, because I don't quite know where to start. I guess I have to start somewhe........ Read more »
Eichhorn TR, Takado Y, Salameh N, Capozzi A, Cheng T, Hyacinthe JN, Mishkovsky M, Roussel C, & Comment A. (2013) Hyperpolarization without persistent radicals for in vivo real-time metabolic imaging. Proceedings of the National Academy of Sciences of the United States of America, 110(45), 18064-9. PMID: 24145405
A few weeks ago, I attended another Evolution and Human Adaptation lecture. The ultimate reason I went to another talk was to expand my mind and learn about the evolution of the human brain, though as always the proximate reason I attended the talk was to avoid working on my NSF draft. This week's topic was "Brain Evolution and Human Uniqueness". Tom Schoenmann, a professor at Indiana University, discussed the strategies that biological anthropologists use to unpack the evolutio........ Read more »
Guo, K., Hall, C., Hall, S., Meints, K., & Mills, D. (2009) Left gaze bias in humans, rhesus monkeys, and domestic dogs. Animal Cognition, 409-418. DOI: 10.1007/s10071-008-0199-3
Odendaal JS, & Meintjes RA. (2003) Neurophysiological correlates of affiliative behaviour between humans and dogs. Veterinary journal (London, England : 1997), 165(3), 296-301. PMID: 12672376
Scientists from Stanford University and the National Oceanic and Atmospheric Administration (NOAA) have discovered that crude oil interrupts a cellular pathway that allows fish heart cells to beat effectively.... Read more »
Fabien Brette, Ben Machado, Caroline Cros, John P. Incardona, Nathaniel L. Scholz, Barbara A. Block. (2014) Crude Oil Impairs Cardiac Excitation-Contraction Coupling in Fish. Science, 343(6172), 772-776. DOI: 10.1126/science.1242747
It is postulated that learning and memory are modulated by synaptic plasticity – molecular changes that result in changes in the synapse morphology and signaling capacity. Local protein translation is considered important for synaptic plasticity. Two works from our lab … Continue reading →... Read more »
Buxbaum AR, Wu B, & Singer RH. (2014) Single β-actin mRNA detection in neurons reveals a mechanism for regulating its translatability. Science (New York, N.Y.), 343(6169), 419-22. PMID: 24458642
Park HY, Lim H, Yoon YJ, Follenzi A, Nwokafor C, Lopez-Jones M, Meng X, & Singer RH. (2014) Visualization of dynamics of single endogenous mRNA labeled in live mouse. Science (New York, N.Y.), 343(6169), 422-4. PMID: 24458643
3D printing is in fashion. Clothes, prosthetic limbs, guns and even pizza, you name it—just about anything can be printed these days. Even living cells.Bioprinting is an emerging technology that promises to revolutionise the field of regenerative medicine. The idea is simple: you load a printer cartridge with cells removed from a patient or grown in the lab, and then print a brand new tissue or organ ready for transplantation. Alternatively, you could print healthy tissue directly onto a patie........ Read more »
Lorber Barbara, Hsiao Wen-Kai, Hutchings Ian M, & Martin Keith R. (2014) Adult rat retinal ganglion cells and glia can be printed by piezoelectric inkjet printing. Biofabrication, 6(1), 15001. DOI: 10.1088/1758-5082/6/1/015001
Ignition—the process of releasing fusion energy equal to or greater than the amount of energy used to confine the fuel—has long been considered the “holy grail” of inertial confinement fusion science.... Read more »
O.A. Hurricane, D.A. Callahan, D. T. Casey, P.M. Celliers, C. Cerjan, E.L. Dewald, T.R. Dittrich, T. Döppner, D.E. Hinkel, L.F. Berzak Hopkins, J.L. Kline, S. Le Pape, T. Ma, A.G. MacPhee, J.L. Milovich, A. Pak, H.-S. Park, P.K. Patel, B.A. Remingt. (2014) Fuel gain exceeding unity in an inertially confined fusion implosion. Nature. DOI: 10.1038/nature13008
Headline news for GM this week was a new study on resistance to potato blight, the results of 3 yrs of field trials at the John Innes Centre in Norwich.
The paper in the Proceedings of the Royal Society B compared non-transgenic Desiree potato plants with GM plants. When blight conditions were severe in 2012, it dramatically reduced yields in the non-GM varieties. Tubers from each block of 16 GM plants weighed 6-13 kg while the non-GM tubers weighed 1.6-5 kg per block.... Read more »
Jonathan D. G. Jones. (2014) Elevating crop disease resistance with cloned genes. Proceedings of the Royal Society B. DOI: 10.1098/rstb.2013.0087
Scott MacIvor has cracked open hundreds of artificial bee nests. But two he peered inside in Toronto gave him pause. Within their containers, the bees he studies had carefully built homes for their young out of plastic debris. Mixed in with the usual construction materials of leaves and mud, MacIvor could clearly see bits of […]The post Urban Bees Build Their Nests with Plastic appeared first on Inkfish.... Read more »
J. Scott MacIvor, & Andrew E. Moore. (2013) Bees collect polyurethane and polyethylene plastics as novel nest materials. Ecosphere, 4(12). DOI: 10.1890/ES13-00308.1
What happens if you drop a ball in a falling elevator and why? Your answer will of course depend on the sophistication of your understanding of the laws of physics. Psychologists in France and the Netherlands have used similar questions to test the understanding of 144 children and teenagers aged 5 to 18 years. The results show how children's naive understanding of gravity matures through different stages as a result of their first-hand experience and exposure to formal teaching and cultural exp........ Read more »
Frappart S, Raijmakers M, & Frède V. (2014) What do children know and understand about universal gravitation? Structural and developmental aspects. Journal of experimental child psychology, 17-38. PMID: 24361806
Today the Daily Mail reports on an exciting new finding: Patricia Gray (University of North Carolina in Greensboro) and Ed Large (University of Connecticut) claim to have shown that bonobo's can synchronise to a beat.
... Read more »
De Waal, Frans B.M. (1988) The Communicative Repertoire of Captive Bonobos (Pan Paniscus) Compared To That of Chimpanzees. Behaviour, 106(3), 183-251. DOI: 10.1163/156853988X00269
Media headlines frequently link young people's widespread use of Facebook with the narcissism of their generation (e.g. "Facebook's 'dark side': study finds link to socially aggressive narcissism). A new investigation involving hundreds of US college students and hundreds of members of the US public has found that it's actually the older generation for whom this claim is more accurate. However, use of Twitter tells another story.First to challenge those Facebook headlines. Shaun Davenport and hi........ Read more »
Shaun W. Davenport, Shawn M. Bergman, Jacqueline Z. Bergman, & Matthew E. Fearrington. (2014) Twitter versus Facebook: Exploring the role of narcissism in the motives and usage of different social media platforms. Computers in Human Behavior. DOI: 10.1016/j.chb.2013.12.011
A recent study just revealed that home made cigarettes are more addictive than the factory-rolled ones. The researchers analysed the tobacco dependence behavior of mice. These had at their disposal the content of ready-made cigarettes, the content of self-made cigarettes, or nicotine. The results showed that mice with self-made cigarette content at hand tended... ... Read more »
Brennan, K. A., Crowther, A., Putt, F., Roper, V., Waterhouse, U. and Truman, P. (2013) Tobacco particulate matter self-administration in rats: differential effects of tobacco type. Addiction Biology. info:/
I've talked about the [almighty] major histocompatibility complex (MHC) before on this blog (see here). The important duties that this biological system performs in relation to identification and communication insofar as antigen presentation and importantly, the process of differentiation between 'self' and 'non-self' from an immunological perspective, are not to be sniffed at.Harold? @ WikipediaI've found myself quite interested in all things MHC (also referring to the human leukocyte anti........ Read more »
Nudel R, Simpson NH, Baird G, O Hare A, Conti-Ramsden G, Bolton PF, Hennessy ER, Monaco AP, Knight JC, Winney B.... (2014) Associations of HLA alleles with specific language impairment. Journal of neurodevelopmental disorders, 6(1), 1. PMID: 24433325
How is it that memories change and yet seem fairly stable? In a recent paper, Bridge and Voss, report studies on changes to memory. (see citation). They looked at a particular memory, the location of an object. They changed the background associated with the object. How does the memory change after the change of background? […]... Read more »
D.J. Bridge, & J.L. Voss. (2014) Hippocampal Binding of Novel Information with Dominant Memory Traces Can Support Both Memory Stability and Change. Journal of Neuroscience, 34(6). DOI: 10.1523/JNEUROSCI.3819-13.2014
Max S. Wicha and Hasan KorkayaNew findings by researchers at the University of Michigan Comprehensive Cancer Center and Georgia Regents University indicate that a protein that fuels an inflammatory pathway does not turn off in breast cancer, resulting in an increase in cancer stem cells.This provides a potential target for treating triple negative breast cancer, the most aggressive form of the disease.The researchers identified a protein, SOCS3, that is highly expressed in normal cells but undet........ Read more »
Kim G, Ouzounova M, Quraishi AA, Davis A, Tawakkol N, Clouthier SG, Malik F, Paulson AK, D'Angelo RC, Korkaya S.... (2014) SOCS3-mediated regulation of inflammatory cytokines in PTEN and p53 inactivated triple negative breast cancer model. Oncogene. PMID: 24531711
Young female soccer players (11 to 14 years) have a high rate of concussions, often continue to play with symptoms, and commonly fail to seek medical attention.... Read more »
O'Kane JW, Spieker A, Levy MR, Neradilek M, Polissar NL, & Schiff MA. (2014) Concussion Among Female Middle-School Soccer Players. JAMA pediatrics. PMID: 24446018
Brain Awareness Week is coming, so I was interested to read today about the University of Minnesota Brain Awareness Program for schools. A paper, published in PLoS ONE a few weeks ago, gives plenty of details about this pioneering educational initiative. But the main reason I’m blogging about it is so I can share this […]The post Do Children Need Brain Awareness? appeared first on Neuroskeptic.... Read more »
Fitzakerley JL, Michlin ML, Paton J, & Dubinsky JM. (2013) Neuroscientists' classroom visits positively impact student attitudes. PloS one, 8(12). PMID: 24358325
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