Post List

  • June 7, 2016
  • 11:21 AM
  • 199 views

EU Puts Forward Ambitious Open Access Target

by Nesru Koroso in United Academics

All publicly-funded research to be fully accessible by 2020.... Read more »

  • June 7, 2016
  • 07:24 AM
  • 199 views

Cytopathogenesis of ZIKV: IFTM and viral entry/Hofbauer cells and the placenta

by thelonevirologist in Virology Tidbits

Zika Virus (ZIKV) is an emerging member of the Flaviviridae that in the past months spread to over 30 countries in the Americas alone that has been associated with the emergence of microcephaly, a condition associated with abnormal brain development, in Brazil and elsewhere.
Recent studies confirmed the presence of ZIKV in the amniotic fluid as well in the brain and CNS of neonates, suggesting that ZIKV can infect embryonal and foetal tissue by crossing the placental barrier. In addition, ZIKV ........ Read more »

Driggers RW, Ho CY, Korhonen EM, Kuivanen S, Jääskeläinen AJ, Smura T, Rosenberg A, Hill DA, DeBiasi RL, Vezina G.... (2016) Zika Virus Infection with Prolonged Maternal Viremia and Fetal Brain Abnormalities. The New England journal of medicine, 374(22), 2142-51. PMID: 27028667  

Cugola, F., Fernandes, I., Russo, F., Freitas, B., Dias, J., Guimarães, K., Benazzato, C., Almeida, N., Pignatari, G., Romero, S.... (2016) The Brazilian Zika virus strain causes birth defects in experimental models. Nature. DOI: 10.1038/nature18296  

Savidis, G., Perreira, J., Portmann, J., Meraner, P., Guo, Z., Green, S., & Brass, A. (2016) The IFITMs Inhibit Zika Virus Replication. Cell Reports. DOI: 10.1016/j.celrep.2016.05.074  

Quicke KM, Bowen JR, Johnson EL, McDonald CE, Ma H, O'Neal JT, Rajakumar A, Wrammert J, Rimawi BH, Pulendran B.... (2016) Zika Virus Infects Human Placental Macrophages. Cell host . PMID: 27247001  

Noronha Ld, Zanluca C, Azevedo ML, Luz KG, & Santos CN. (2016) Zika virus damages the human placental barrier and presents marked fetal neurotropism. Memorias do Instituto Oswaldo Cruz, 111(5), 287-93. PMID: 27143490  

Garcez PP, Loiola EC, Madeiro da Costa R, Higa LM, Trindade P, Delvecchio R, Nascimento JM, Brindeiro R, Tanuri A, & Rehen SK. (2016) Zika virus impairs growth in human neurospheres and brain organoids. Science (New York, N.Y.), 352(6287), 816-8. PMID: 27064148  

Hamel R, Dejarnac O, Wichit S, Ekchariyawat P, Neyret A, Luplertlop N, Perera-Lecoin M, Surasombatpattana P, Talignani L, Thomas F.... (2015) Biology of Zika Virus Infection in Human Skin Cells. Journal of virology, 89(17), 8880-96. PMID: 26085147  

Tang H, Hammack C, Ogden SC, Wen Z, Qian X, Li Y, Yao B, Shin J, Zhang F, Lee EM.... (2016) Zika Virus Infects Human Cortical Neural Progenitors and Attenuates Their Growth. Cell stem cell, 18(5), 587-90. PMID: 26952870  

Miner JJ, Cao B, Govero J, Smith AM, Fernandez E, Cabrera OH, Garber C, Noll M, Klein RS, Noguchi KK.... (2016) Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise. Cell, 165(5), 1081-91. PMID: 27180225  

Bayer A, Lennemann NJ, Ouyang Y, Bramley JC, Morosky S, Marques ET Jr, Cherry S, Sadovsky Y, & Coyne CB. (2016) Type III Interferons Produced by Human Placental Trophoblasts Confer Protection against Zika Virus Infection. Cell host , 19(5), 705-12. PMID: 27066743  

Azari, H., & Reynolds, B. (2016) In Vitro Models for Neurogenesis. Cold Spring Harbor Perspectives in Biology, 8(6). DOI: 10.1101/cshperspect.a021279  

Young OM, Tang Z, Niven-Fairchild T, Tadesse S, Krikun G, Norwitz ER, Mor G, Abrahams VM, & Guller S. (2015) Toll-like receptor-mediated responses by placental Hofbauer cells (HBCs): a potential pro-inflammatory role for fetal M2 macrophages. American journal of reproductive immunology (New York, N.Y. : 1989), 73(1), 22-35. PMID: 25345551  

Xu DZ, Yan YP, Zou S, Choi BC, Wang S, Liu P, Bai G, Wang X, Shi M, & Wang X. (2001) Role of placental tissues in the intrauterine transmission of hepatitis B virus. American journal of obstetrics and gynecology, 185(4), 981-7. PMID: 11641689  

Smith S, Weston S, Kellam P, & Marsh M. (2014) IFITM proteins-cellular inhibitors of viral entry. Current opinion in virology, 71-7. PMID: 24480526  

  • June 7, 2016
  • 03:09 AM
  • 194 views

Interest in romantic relationships is high in autism

by Paul Whiteley in Questioning Answers

It's official: "the vast majority of high-functioning adults with ASD [autism spectrum disorder] are interested in romantic relationships." Yes, the scientific findings reported by Sandra Strunz and colleagues [1] have said as much.Sorry to be so sarcastic about them but coming from a place where the words 'the bleedin' obvious' are commonly used, I couldn't believe that in 2016 anyone would genuinely believe otherwise. Yes, I know the autism awareness et al message still has some........ Read more »

  • June 7, 2016
  • 01:06 AM
  • 224 views

Advil Increases Social Pain (if you're male)

by The Neurocritic in The Neurocritic

Headache, Guillaume DELEBARRE (Guigui-Lille)A recent neuroessay in the New York Times asked, Can Tylenol Help Heal a Broken Heart?What’s crazy about the pain of a broken heart is that your body perceives it as physical pain.No it does not. Do you feel heartbroken every time you stub your toe?Well... I guess the social pain = physical pain isomorphism is a one way street. Anyway, the author continued:In research published in 2010, scientists found that acetaminophen can reduce physical and neur........ Read more »

  • June 6, 2016
  • 01:52 PM
  • 210 views

The truth is out there: Scientists unlock X-Files DNA mystery

by Dr. Jekyll in Lunatic Laboratories

Scientists have unlocked a crucial part of the mystery as to how our DNA can replicate and repair itself - something which is essential for all life forms. The new research has revealed how branched DNA molecules are removed from the iconic double-helical structure -a process which scientists have been looking to unlock for over 20 years.

... Read more »

AlMalki, F., Flemming, C., Zhang, J., Feng, M., Sedelnikova, S., Ceska, T., Rafferty, J., Sayers, J., & Artymiuk, P. (2016) Direct observation of DNA threading in flap endonuclease complexes. Nature Structural . DOI: 10.1038/nsmb.3241  

  • June 6, 2016
  • 12:36 PM
  • 236 views

Love, War and Genital Shape

by Miss Behavior in The Scorpion and the Frog

The size and shape of your junk may depend on how much sex your ancestors had… that is, at least, if you are a burying beetle. Buring beetles caught in the act. Photo by Jena Johnson. Burying beetles are unusual among insects in that they provide parental care and are often monogamous. When burying beetle pairs find a small dead bird or rodent, they pluck it bald, coat it in antibacterial and antifungal body secretions, and dig a hole around it. The female lays her eggs around the carcass-ba........ Read more »

  • June 6, 2016
  • 11:50 AM
  • 192 views

Neuroscience Medicine: The Time Has Come

by William Yates, M.D. in Brain Posts

As basic and clinical sciences advance, it becomes increasing important to understand the role of multidisciplinary efforts in scientific progress. In this post, I propose rethinking and renaming the medically-related neuroscience disciplines into a new specialty called neuroscience medicine.Basic neuroscience research has evolved and emerged as a powerful discipline due to the increasing use of multidisciplinary research teams. Basic neuroscience involves collaboration of various scientifi........ Read more »

  • June 6, 2016
  • 11:30 AM
  • 206 views

The Pantanal Diaries IV: Not Ready To Leave

by Chiara Civardi in United Academics

Venture into the Brazilian swamp with Chiara and the Wildlife Conservation Society.... Read more »

Barros, E., Pashanasi, B., Constantino, R., & Lavelle, P. (2002) Effects of land-use system on the soil macrofauna in western Brazilian Amazonia. Biology and Fertility of Soils, 35(5), 338-347. DOI: 10.1007/s00374-002-0479-z  

  • June 6, 2016
  • 11:08 AM
  • 171 views

Best Laid Plans

by AG McCluskey in Zongo's Cancer Diaries

REVEALED: UK cancer scientists' pensions invested in tobacco.

....And this UK cancer scientist, for one, is Not Happy....... Read more »

AG McCluskey. (2016) Best Laid Plans. Zongo's Cancer Diaries. info:/

  • June 6, 2016
  • 10:34 AM
  • 187 views

Burning seaweed to make glass and avoid a lumpy neck

by Rosin Cerate in Rosin Cerate

Seaweed is one of those tricky biological groups, as membership isn't just about being a close relative. It typically includes plant-like organisms found among several types of algae - green, brown, and red - and depending on who you're talking to also includes masses of cyanobacteria (which are distant relatives of algae). Functionally, all seaweeds enjoy growing in salty water and use the sun to manufacture sugary meals for themselves. Their need for sun means they are found in sunlit coastal ........ Read more »

  • June 6, 2016
  • 07:02 AM
  • 105 views

Acetaminophen: Or why you have to read more than the  headlines when it comes to research

by Rita Handrich in The Jury Room

John Oliver recently took on mass media coverage of scientific findings on his HBO show, Last Week Tonight. The result is a searing video mocking the distortions and misinterpretations (and even flat-out lies) about research findings as presented in mass media. Since his episode aired (a link to the video is at the end of […]

Related posts:
Reports of novel or contradictory health research reduces public trust  in science
Top 10 Most Read Posts During 2012!
Pew Research says 15% of Ame........ Read more »

  • June 6, 2016
  • 06:04 AM
  • 97 views

How depression affects couples – in their own words

by BPS Research Digest in BPS Research Digest

Depression has been called a "we-disease" because when the dark clouds arrive, it's not just the depressed person who is affected, but all those close to them. A new study in the Journal of Social and Personal Relationship explored these spillover effects in the context of romantic couples, where one or both individuals have a diagnosis of clinical depression. The US study broke new ground by asking both partners in each couple to provide their perspective on how depression had affected their re........ Read more »

Sharabi, L., Delaney, A., & Knobloch, L. (2015) In their own words: How clinical depression affects romantic relationships. Journal of Social and Personal Relationships, 33(4), 421-448. DOI: 10.1177/0265407515578820  

  • June 6, 2016
  • 04:30 AM
  • 164 views

Many NCAA Clinicians Fail to Screen Mental Health

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Only 39% of respondents from NCAA institutions indicated that they had a written mental health screening plan. There is a wide variability between mental health screening practices among NCAA institutions.... Read more »

  • June 6, 2016
  • 03:00 AM
  • 191 views

C-reactive protein "may be a causal risk factor for schizophrenia"

by Paul Whiteley in Questioning Answers

Although the public perception of science is that researchers go around 'proving' or 'disproving' that A leads to B or X causes Y, it is still surprisingly rare to see the word 'causal' in many areas of peer-reviewed research. Aside from the fact that science generally works around the concept of 'probability' - producing data pertinent to discussions on whether something is more or less likely to be true/false - most science is not so forthright in its conclusions. Certainly science covering th........ Read more »

Inoshita M, Numata S, Tajima A, Kinoshita M, Umehara H, Nakataki M, Ikeda M, Maruyama S, Yamamori H, Kanazawa T.... (2016) A significant causal association between C-reactive protein levels and schizophrenia. Scientific reports, 26105. PMID: 27193331  

  • June 5, 2016
  • 02:03 PM
  • 174 views

Counting exosome secretion

by Gal Haimovich in Green Fluorescent Blog

Last month I wrote a post about exosome internalization by recipient cells.  One of the topics I discussed was the lack of good quantitative data in the exosomal field, and what the current data tells us about the efficiency and … Continue reading →... Read more »

  • June 5, 2016
  • 01:05 AM
  • 234 views

Why does English spread in global academia?

by Jinhyun Cho in Language on the Move

The Linguistic Ethnography Forum’s e-seminar devoted to Ingrid Piller’s recent book Linguistic Diversity and Social Justice: An Introduction to Applied...... Read more »

Piller, I., & Cho, J. (2013) Neoliberalism as language policy. Language in Society, 42(01), 23-44. DOI: 10.1017/S0047404512000887  

  • June 4, 2016
  • 07:40 PM
  • 173 views

Trauma research must be Open Access

by Eva Alisic in Trauma Recovery

We recently examined how global and how open the literature on Posttraumatic Stress Disorder is.

Not so global, and not so open.

Only 13% of the publications of 2012 regarded samples in low- or middle-income countries and 58% were behind a paywall.

It worries me that practicing psychologists can’t access the latest research on therapy effectiveness...
... Read more »

  • June 4, 2016
  • 03:40 AM
  • 198 views

Antibiotic brain part 2

by Paul Whiteley in Questioning Answers

"Mouse study finds link between gut bacteria and neurogenesis" went the press release accompanying the paper by Luisa Möhle and colleagues [1] (open-access). Describing the results of a mouse study - that's MOUSE study - researchers reported that "treatment of adult mice with antibiotics decreases hippocampal neurogenesis and memory retention."The antibiotic mix used on study mice was quite an aggressive one: "ampicillin plus sulbactam (1.5 g/l; Pfizer), vancomycin (500 mg/l; Cell Pharm), ........ Read more »

Luisa Möhle, Daniele Mattei, Markus M. Heimesaat, Stefan Bereswill, André Fischer, Marie Alutis, Timothy French, Dolores Hambardzumyan, Polly Matzinger, Ildiko R. Dunay.... (2016) Ly6Chi Monocytes Provide a Link between Antibiotic-Induced Changes in Gut Microbiota and Adult Hippocampal Neurogenesis. Cell Reports. info:/10.1016/j.celrep.2016.04.074

  • June 3, 2016
  • 02:55 PM
  • 259 views

Zika virus directly infects brain cells and evades immune system detection

by Dr. Jekyll in Lunatic Laboratories

The mosquito-borne Zika virus linked to microcephaly and other neurological problems in newborns of affected mothers directly infects the brain progenitor cells destined to become neurons. The team of researchers used a strain of Zika currently impacting the Americas, and found that the virus infects about 20 percent of cells on average, evades immune system detection, and continues to replicate for weeks.

... Read more »

  • June 3, 2016
  • 01:42 PM
  • 143 views

The Myth of the Optimism Bias?

by Neuroskeptic in Neuroskeptic_Discover

Are humans natural, irrational optimists? According to many psychologists, humans show a fundamental optimism bias, a tendency to underestimate our chances of suffering negative events. It's said that when thinking about harmful events, such as contracting cancer, most people believe that their risk is lower than that of 'the average person'. So, on average, people rate themselves as safer than the average. Moreover, people are also said to show biased belief updating. Faced with evidence that t........ Read more »

Punit Shah, Adam J. L. Harris, Geoffrey Bird, Caroline Catmur, & Ulrike Hahn. (2016) A Pessimistic View of Optimistic Belief Updating. Cognitive Psychology. info:/

join us!

Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.

If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.

Register Now

Research Blogging is powered by SMG Technology.

To learn more, visit seedmediagroup.com.