Should we have people providing "fake" acupuncture in the Emergency Department?
If so, how should we do this?
Since it is not the acupuncture, but the patient's reaction to the "ceremony of the placebo" that appears to be providing the pain relief, how many different ways might we vary the "treatment" to improve the placebo effect?... Read more »
Grissa, M., Baccouche, H., Boubaker, H., Beltaief, K., Bzeouich, N., Fredj, N., Msolli, M., Boukef, R., Bouida, W., & Nouira, S. (2016) Acupuncture vs intravenous morphine in the management of acute pain in the ED. The American Journal of Emergency Medicine. DOI: 10.1016/j.ajem.2016.07.028
Espay, A., Norris, M., Eliassen, J., Dwivedi, A., Smith, M., Banks, C., Allendorfer, J., Lang, A., Fleck, D., Linke, M.... (2015) Placebo effect of medication cost in Parkinson disease: A randomized double-blind study. Neurology, 84(8), 794-802. DOI: 10.1212/WNL.0000000000001282
Waber RL, Shiv B, Carmon Z, Ariely D. (2008) Commercial Features of Placebo and Therapeutic Efficacy. JAMA, 299(9), 1016. DOI: 10.1001/jama.299.9.1016
Cherkin, D., Sherman, K., Avins, A., Erro, J., Ichikawa, L., Barlow, W., Delaney, K., Hawkes, R., Hamilton, L., Pressman, A.... (2009) A Randomized Trial Comparing Acupuncture, Simulated Acupuncture, and Usual Care for Chronic Low Back Pain. Archives of Internal Medicine, 169(9), 858. DOI: 10.1001/archinternmed.2009.65
Goldman, R., Stason, W., Park, S., Kim, R., Schnyer, R., Davis, R., Legedza, A., & Kaptchuk, T. (2008) Acupuncture for Treatment of Persistent Arm Pain Due to Repetitive Use. The Clinical Journal of Pain, 24(3), 211-218. DOI: 10.1097/AJP.0b013e31815ec20f
There's a reason it's called a gut feeling. The brain and the gut are connected by intricate neural networks that signal hunger and satiety, love and fear, even safety and danger. These networks employ myriad chemical signals that include dopamine, a powerful neurotransmitter most famous for its role in reward and addiction.
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Xiou Cao, & Alejandro Aballay. (2016) Neural inhibition of dopaminergic signaling enhances immunity in a cell non-autonomous manner. Current Biology. info:/http://dx.doi.org/10.1016/j.cub.2016.06.036
There was always that nagging feeling of not being accepted, of whispers behind his back. They pretended to be open-minded, but in reality not belonging to the group of professionals was reason enough to dismiss his work and findings. In their eyes, he was just a solicitor. A hobbyist. He was tolerated, but their derision […]... Read more »
De Groote, I., Flink, L., Abbas, R., Bello, S., Burgia, L., Buck, L., Dean, C., Freyne, A., Higham, T., Jones, C.... (2016) New genetic and morphological evidence suggests a single hoaxer created ‘Piltdown man’. Royal Society Open Science, 3(8), 160328. DOI: 10.1098/rsos.160328
"In this nationwide sample of live births we observed no association between induction of labor and offspring ASD [autism spectrum disorder] within sibling comparison. Our findings suggest that concern for ASD should not factor into the clinical decision about whether to induce labor."So said the findings reported by Anna Sara Oberg and colleagues  supposedly providing some reassurance to mums-to-be and other groups around the likelihood of offspring autism when birth or l........ Read more »
Oberg, A., D’Onofrio, B., Rickert, M., Hernandez-Diaz, S., Ecker, J., Almqvist, C., Larsson, H., Lichtenstein, P., & Bateman, B. (2016) Association of Labor Induction With Offspring Risk of Autism Spectrum Disorders. JAMA Pediatrics. DOI: 10.1001/jamapediatrics.2016.0965
Last week, I discussed how male quality in birds may be related to their song. How do males evaluate females in return? The answer may lie in their nests.... Read more »
Cantarero, A., López-Arrabé, J., Plaza, M., Saavedra-Garcés, I., & Moreno, J. (2016) Males feed their mates more and take more risks for nestlings with larger female-built nests: an experimental study in the Nuthatch Sitta europaea. Behavioral Ecology and Sociobiology, 70(8), 1141-1150. DOI: 10.1007/s00265-016-2122-2
If you read my blog often, it's no surprise I suffer from PTSD, depression, and anxiety issues. Maybe it's from my military service, but maybe it's my father's, or his father's, maybe it's an insidious family legacy that was just never noticed. This is because having both parents and grandparents with major depressive disorder (MDD) was associated with higher risk of MDD for grandchildren, which could help identify those who may benefit from early intervention.
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Myrna M. Weissman, PhD, Obianuju O. Berry, MD, MPH, Virginia Warner, DrPH, Marc J. Gameroff, PhD, Jamie Skipper, MS, Ardesheer Talati, PhD, Daniel J. Pilowsky, MD, MPH, & Priya Wickramaratne, PhD. (2016) A 30-Year Study of 3 Generations at High Risk and Low Risk for Depression. JAMA Psychiatry . info:/10.1001/jamapsychiatry.2016.1586
Scientists tracked down the evidence for a common statement about bite strength in dogs – and found it lacking.Have you ever read comments about the strength of a dog’s jaw when it bites? These statements are often made in relation to certain types of dog, like pit bulls. Maybe some people take it as fact. But what if it’s not true?A recent paper by Dr. Gary Patronek (Cummings School of Veterinary Medicine, Tufts University) et al traced citations in the literature and went back to the ori........ Read more »
Patronek, G., Bradley, J., & Cleary, D. (2016) Who is minding the bibliography? Daisy chaining, dropped leads, and other bad behavior using examples from the dog bite literature. Journal of Veterinary Behavior: Clinical Applications and Research, 17-19. DOI: 10.1016/j.jveb.2016.06.004
One cannot over estimate the ways that water affects life on Earth. Beyond its chemical properties, some animals have evolved to substitute water for a rigid skeleton. Hydrostatic skeletons can be used for support, but also as water vascular systems that provide pressure for vascular transport and respiration. A recent review by William H. Kier sheds light on the interactions of different fibers and tissues in water based skeletons. Yet some plants can withstand a loss of 60% of their water, whe........ Read more »
A hands-free ultrasound unit at 1 MHz failed to increase the temperature deep in the gastrocnemius after 10 minutes.... Read more »
Melanson, H., Draper, D., Mitchell, U., & Eggett, D. (2016) Comparison of Hands-free Ultrasound and Traditional Ultrasound for Therapeutic Treatment. Athletic Training , 8(4), 177-184. DOI: 10.3928/19425864-20160505-01
Although research stories stating a link (an association if you will) between condition A and factor X make for interesting reading, not all science is so blessed with such news-worthy findings. That's not to say that 'negative findings' are any less important than the 'hey, we found this...' studies, just that they don't perhaps tend to grab the headlines as much as those finding something.In saying all that I'm standing up for negative findings today and some rather interesting science reporte........ Read more »
Duringer J, Fombonne E, & Craig M. (2016) No Association between Mycotoxin Exposure and Autism: A Pilot Case-Control Study in School-Aged Children. Toxins, 8(7). PMID: 27447670
It's not a fad diet, it is an actual diet -- as in the way a person eats normally -- and it may do more than just help your waistline. The Mediterranean diet can improve your mind, as well your heart.
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Hardman, R., Kennedy, G., Macpherson, H., Scholey, A., & Pipingas, A. (2016) Adherence to a Mediterranean-Style Diet and Effects on Cognition in Adults: A Qualitative Evaluation and Systematic Review of Longitudinal and Prospective Trials. Frontiers in Nutrition. DOI: 10.3389/fnut.2016.00022
In my previous post, I highlighted a recent study of genetics and major depression from the 23andMe database.I have had a chance to review this manuscript in more detail. One of the findings of interest involved secondary marker or secondary phenotypes.Fifteen genetic loci were identified in this 23andMe sample using a discovery and replication data set.Secondary phenotypes with the highest correlation with the 17 SNPs identified in the study included (effect) :Taking a selective serotonin reupt........ Read more »
Hyde CL, Nagle MW, Tian C, Chen X, Paciga SA, Wendland JR, Tung JY, Hinds DA, Perlis RH, & Winslow AR. (2016) Identification of 15 genetic loci associated with risk of major depression in individuals of European descent. Nature genetics. PMID: 27479909
Fermi (1949) introduced a fundamental stochastic process to solve the problem of particle energization (heating and/or acceleration) in space and astrophysical plasmas. The initial idea of Fermi with randomly moving scatterers (magnetic clouds), was soon replaced with a spectrum of low amplitude (δΒ/Β... Read more »
by L. Vlahos, T. Pisokas, H. Isliker, V. Tsiolis and A. Anastasiadis. (2016) Particle Acceleration and heating by turbulent reconnection. ApJ. info:/
"Comorbid anxiety symptoms are ubiquitous among psychiatric patients with mood or schizophrenia spectrum disorders, and in almost half of them, reportedly severe."So said the findings reported by Karpov and colleagues  who sought to put some further research flesh on to the bones of the idea that clinically relevant anxiety symptoms might not be unstrange bedfellows with a variety of other psychiatric labels.Based on the analysis of various patient groups included in the "Helsinki University ........ Read more »
Karpov, B., Joffe, G., Aaltonen, K., Suvisaari, J., Baryshnikov, I., Näätänen, P., Koivisto, M., Melartin, T., Oksanen, J., Suominen, K.... (2016) Anxiety symptoms in a major mood and schizophrenia spectrum disorders. European Psychiatry, 1-7. DOI: 10.1016/j.eurpsy.2016.04.007
Is the drop of a running shoe associated with injury risk?... Read more »
Malisoux, L., Chambon, N., Urhausen, A., & Theisen, D. (2016) Influence of the Heel-to-Toe Drop of Standard Cushioned Running Shoes on Injury Risk in Leisure-Time Runners: A Randomized Controlled Trial With 6-Month Follow-up. The American Journal of Sports Medicine. DOI: 10.1177/0363546516654690
In an effort to reduce pain or fix other health problems, some people will submit to having suction temporarily applied to various regions of their skin, usually the neck, shoulders, and back, via a collection of plastic or glass cups. This is known as cupping, and is a great way to embrace your inner Polkaroo.... Read more »
Pesticides beekeepers are using to improve honeybee health may actually be harming the bees by damaging the bacteria communities in their guts. The discovery is a concern because alterations can affect the gut's ability to metabolize sugars and peptides, processes that are vital for honeybee health.
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Madhavi Kakumanu, Alison M. Reeves, Troy Anderson, Richard R. Rodrigues, & Mark A. Williams. (2016) Honey bee gut microbiome is altered by in-hive pesticide exposures. Frontiers in Microbiology. info:/10.3389/fmicb.2016.01255
Not a very good showing, eh?Here's our latest study on mediumship: "Prediction of Mortality Based on Facial Characteristics". Available here: https://t.co/jVMHmF07Dj— Dean Radin (@DeanRadin) May 21, 2016In the study,“Participants were asked to press a button if they thought the person in a photo was living or deceased. Overall mean accuracy on this task was 53.8%, where 50% was expected by chance (p < 0.004, two-tail). Statistically significant accuracy was independently obtained in 5 of ........ Read more »
Delorme, A., Pierce, A., Michel, L., & Radin, D. (2016) Prediction of Mortality Based on Facial Characteristics. Frontiers in Human Neuroscience. DOI: 10.3389/fnhum.2016.00173
I tread carefully in discussing the findings reported by Karola Dillenburger and colleagues  (open-access) on the question of "knowledge and training with regards to autism" received by "health, social care, and education staff who work within the statutory autism services sector in the UK." The observation that "an acute lack of autism-specific training that has detrimental impacts" was apparent is a worrying sign indeed.Although not intimately involved in the autism services sector, I ........ Read more »
Feeling stiff first thing in the morning? It's not your imagination, new research has found a protein created by the body's "biological clock" that actively represses inflammatory pathways within the affected limbs during the night. This protein, called CRYPTOCHROME, has proven anti-inflammatory effects in cultured cells and presents new opportunities for the development of drugs that may be used to treat inflammatory diseases and conditions, such as arthritis.
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Hand, L., Hopwood, T., Dickson, S., Walker, A., Loudon, A., Ray, D., Bechtold, D., & Gibbs, J. (2016) The circadian clock regulates inflammatory arthritis. The FASEB Journal. DOI: 10.1096/fj.201600353R
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