While it is already possible to obtain in vitro pluripotent cells (ie, cells capable of generating all tissues of an embryo) from any cell type, researchers from Maria-Elena Torres-Padilla’s team have pushed the limits of science even further. They managed to obtain totipotent cells with the same characteristics as those of the earliest embryonic stages and with even more interesting properties.... Read more »
Ishiuchi, T., Enriquez-Gasca, R., Mizutani, E., Bošković, A., Ziegler-Birling, C., Rodriguez-Terrones, D., Wakayama, T., Vaquerizas, J., & Torres-Padilla, M. (2015) Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly. Nature Structural . DOI: 10.1038/nsmb.3066
Just how much monkey business is there in monkey sex? In groups with alpha males, monkeys lower on the totem pole may have to sneak around to mate. How well they conceal their activities can shed light on the cognitive powers of primates.
Macaques are monkeys that live in troops with complex social hierarchies. High-ranking males may have dibs on mating with all the females in the group. But females give non-alpha males a chance too, and some studies have found that these hookups happen m........ Read more »
Overduin-de Vries, A., Spruijt, B., de Vries, H., & Sterck, E. (2015) Tactical deception to hide sexual behaviour: macaques use distance, not visibility. Behavioral Ecology and Sociobiology, 69(8), 1333-1342. DOI: 10.1007/s00265-015-1946-5
MedicalResearch.com Interview with: Elina Einiö PhD Postdoctoral Researcher Population Research Unit, Department of Social Research University of Helsinki Finland Medical Research: What is the background for this study? Response: Some previous studies have shown that young fatherhood is associated with … Continue reading →
The post Young Fathers May Die Early appeared first on MedicalResearch.com Medical Research Interviews and News.
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Elina Einiö PhD. (2015) Young Fathers May Die Early. MedicalResearch.com. info:/
The paper by Reza Kiani and colleagues  (open-access available here) detailing the presence of anti-N-methyl-d-aspartate (NMDA) receptor encephalitis in two people "with autism and intellectual disability presenting with neuropsychiatric symptoms of catatonia and neuroleptic malignant syndrome" caught my eye recently.Having previously talked about anti-NMDA-receptor encephalitis and autism in a previous blog post (see here) back in 2013 with the emphasis on a possible link to 'autis........ Read more »
Kiani R, Lawden M, Eames P, Critchley P, Bhaumik S, Odedra S, & Gumber R. (2015) Anti-NMDA-receptor encephalitis presenting with catatonia and neuroleptic malignant syndrome in patients with intellectual disability and autism. BJPsych bulletin, 39(1), 32-5. PMID: 26191422
MedicalResearch.com Interview with: Carsten C. Skarke MD Research Assistant Professor of Medicine McNeil Fellow in Translational Medicine Institute for Translational Medicine and Therapeutics Perelman School of Medicine University of Pennsylvania Medical Research: What is the background for this study? What … Continue reading →
The post No Evidence of Anti-Inflammatory Mediators From Fish Oil Ingestion appeared first on MedicalResearch.com Medical Research Interviews and News.
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Our study provides no evidence supporting the role of SPMs in mediating an anti-inflammatory action of fish oil. (2015) No Evidence of Anti-Inflammatory Mediators From Fish Oil Ingestion. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dong-Wook Kim Center for Genome Engineering, Institute for Basic Science Yonsei University College of Medicine Seoul, Korea Medical Research: What is the background for this study? Response: Hemophilia A is an X-linked genetic disorder caused by mutations … Continue reading →
The post Patient-Derived Stem Cells May Be Able To Reverse Hemophilia A appeared first on MedicalResearch.com Medical Research Interviews and News.
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Dong-Wook Kim. (2015) Patient-Derived Stem Cells May Be Able To Reverse Hemophilia A. MedicalResearch.com. info:/
Researchers have devised an entirely new approach to vaccines – creating immunity without vaccination. The team has demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen-based vaccination. Importantly, this approach, termed DMAb, was rapid, protecting animals within a week of administration.... Read more »
Flingai, S., Plummer, E., Patel, A., Shresta, S., Mendoza, J., Broderick, K., Sardesai, N., Muthumani, K., & Weiner, D. (2015) Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy. Scientific Reports, 12616. DOI: 10.1038/srep12616
Phew! One of my post-doc papers is finally out in Nature Neuroscience, “Oscillatory dynamics coordinating human frontal networks in support of goal maintenance” (link). (Parenthetical: if this kind of thing interests you, feel free to drop me an email and/or drop by my lab’s posters at SfN (PDF)!) I can’t begin to express, within the constraints of my literary ability, […]... Read more »
Voytek B, Kayser AS, Badre D, Fegen D, Chang EF, Crone NE, Parvizi J, Knight RT, & D'Esposito M. (2015) Oscillatory dynamics coordinating human frontal networks in support of goal maintenance. Nature neuroscience. PMID: 26214371
The art of persuasion is often complex and diverse, but today’s study also shows how it can be simple and elegant. Here’s a surprisingly easy way to diminish the automatic, knee-jerk and distrusting reaction to scientific findings. Tell your listeners about scientific consensus. Today’s researchers call consensus a “gateway belief” that results in the ability […]
Simple Jury Persuasion: Educating jurors about science may have no effect
Simple Jury Persuasion: The........ Read more »
van der Linden SL, Leiserowitz AA, Feinberg GD, & Maibach EW. (2015) The scientific consensus on climate change as a gateway belief: experimental evidence. PloS one, 10(2). PMID: 25714347
Dozens of small, fiber-wrapped bundles discovered in a cave in Arizona have been found to contain wild tobacco, the first scientific evidence suggesting that Ancestral Puebloans of the prehistoric Southwest chewed tobacco for personal use, archaeologists say.
... Read more »
Adams, K., Johnson, K., & Murphy, T. (2015) Prehistoric Puebloan yucca ( ) quids with wild tobacco ( ) contents: Molecular and morphological evidence from Antelope Cave, northwestern Arizona . Journal of Field Archaeology, 40(3), 310-324. DOI: 10.1179/2042458214Y.0000000006
The nose is an early warning system, urging us to look closer at what we are planning to put in our mouths. But it’s not just alerting us to questionable food. Past research using economic games has shown that when we’re suspicious of a smell, this emotion can spill into social situations, affecting how trusting we are towards others. Now a new study shows that even without the involvement of other people to trust or distrust, smell can make us suspicious of ideas and concepts – and this a........ Read more »
Lee, D., Kim, E., & Schwarz, N. (2015) Something smells fishy: Olfactory suspicion cues improve performance on the Moses illusion and Wason rule discovery task. Journal of Experimental Social Psychology, 47-50. DOI: 10.1016/j.jesp.2015.03.006
Question 1: Does your child ever point with their index finger to ask for something?Question 2: Is your child able to imitate you or your actions, for example if you pull a face?Question 3: Does your child ever use pretend play, for example to talk on a phone or take care of a doll?Question 4: Does your child look at something across a room when you point to it?Question 5: Does your child understand what people say?Question 6: Does your child ever bring an object to you to show you something?The........ Read more »
Kamio, Y., Haraguchi, H., Stickley, A., Ogino, K., Ishitobi, M., & Takahashi, H. (2015) Brief Report: Best Discriminators for Identifying Children with Autism Spectrum Disorder at an 18-Month Health Check-Up in Japan. Journal of Autism and Developmental Disorders. DOI: 10.1007/s10803-015-2527-1
Concerns about perfectionism can sabotage success at work, school or on the playing field, leading to stress, burnout and potential health problems, according to new research. In the first meta-analysis of the relationship between perfectionism and burnout, researchers analyzed the findings from 43 previous studies conducted over the past 20 years. It turns out perfectionism isn’t all bad.... Read more »
Hill, A., & Curran, T. (2015) Multidimensional Perfectionism and Burnout: A Meta-Analysis. Personality and Social Psychology Review. DOI: 10.1177/1088868315596286
In a new paper just out in Neuron, researchers Timothy Laumann and colleagues present an in-depth analysis of the functional connectivity of a single human brain.
The brain in question belongs to neuroscientist Russ Poldrack, and he's one of the authors of the paper. Poldrack was fMRI scanned a total of 84 times over a period of 532 days. The goal of this intense scanning schedule was to provide a detailed analysis of the functional connectivity of an individual brain.
Previous studies... Read more »
Laumann TO, Gordon EM, Adeyemo B, Snyder AZ, Joo SJ, Chen MY, Gilmore AW, McDermott KB, Nelson SM, Dosenbach NU.... (2015) Functional System and Areal Organization of a Highly Sampled Individual Human Brain. Neuron. PMID: 26212711
By the Brazilian Forum of Public Health Journals Editors and the Associação Brasileira de Saúde Coletiva (Abrasco, Brazilian Public Health Association) … Read More →... Read more »
Vessuri, H., Guedon, J., & Cetto, A. (2013) Excellence or quality? Impact of the current competition regime on science and scientific publishing in Latin America and its implications for development. Current Sociology, 62(5), 647-665. DOI: 10.1177/0011392113512839
MedicalResearch.com Interview with: Prof. Sante D. Pierdomenico Associate Professor of Internal Medicine University “Gabriele d’Annunzio” Chieti-Pescara – Italy Medical Research: What is the background for this study? What are the main findings? Dr. Pierdomenico: Though a peak incidence of cardiovascular … Continue reading →
The post Blood Pressure Dippers May React Differently to Morning Blood Pressure Surge appeared first on MedicalResearch.com Medical Resea........ Read more »
Prof. Sante D. Pierdomenico. (2015) Blood Pressure Dippers May React Differently to Morning Blood Pressure Surge . MedicalResearch.com. info:/
MedicalResearch.com Interview with: Christos Nikolaidis Ph.D. Laboratory of Pharmacology Medical School, Democritus University of Thrace Dragana, Alexandroupolis Greece Medical Research: What is the background for this study? Response: Epigenetic changes are part of the natural history of cervical neoplasia. Tracking … Continue reading →
The post Epigenetic Biomarker May Improve Cervical Cancer Screening appeared first on MedicalResearch.com Medical Research Interviews and News.
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Christos Nikolaidis Ph.D. (2015) Epigenetic Biomarker May Improve Cervical Cancer Screening. MedicalResearch.com. info:/
R2D3R2D3 recently had a fantastic Visual Introduction to Machine Learning, using the classification of homes in San Francisco vs. New York as their example. As they explain quite simply: In machine learning, computers apply statistical learning techniques to automatically identify patterns in data. These techniques can be used to make highly accurate predictions. You should really head over there right now to view it, because it's very impressive.Computational neuroscience types are using machin........ Read more »
Sato, J., Moll, J., Green, S., Deakin, J., Thomaz, C., & Zahn, R. (2015) Machine learning algorithm accurately detects fMRI signature of vulnerability to major depression. Psychiatry Research: Neuroimaging. DOI: 10.1016/j.pscychresns.2015.07.001
Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for the body’s immune cells, leaving them too physically drained to fight the disease, according to new research. Cancer Research UK-funded scientists have discovered that the cells in neuroblastoma – a rare type of childhood cancer that affects nerve cells – produce a molecule that breaks down arginine, one of the building blocks of proteins and an essential energy source for immune cells.... Read more »
Mussai, F., Egan, S., Hunter, S., Webber, H., Fisher, J., Wheat, R., McConville, C., Sbirkov, Y., Wheeler, K., Bendle, G.... (2015) Neuroblastoma Arginase Activity Creates an Immunosuppressive Microenvironment That Impairs Autologous and Engineered Immunity. Cancer Research. DOI: 10.1158/0008-5472.CAN-14-3443
MedicalResearch.com Interview with: Dr. Rosalind Arden Centre for Philosophy of Natural & Social Science London School of Economics London MedicalResearch: What is the background for this study? What are the main findings? Dr. Arden: We’ve known for a while that … Continue reading →
The post Genes May Explain Why Smarter People Live Longer appeared first on MedicalResearch.com Medical Research Interviews and News.
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Dr. Rosalind Arden. (2015) Genes May Explain Why Smarter People Live Longer. MedicalResearch.com. info:/
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