Birt–Hogg–Dubé syndrome (BHD) is caused by germline mutations in the FLCN gene and characterized by fibrofolliculomas, lung cysts, spontaneous pneumothorax and renal tumours. The stretch hypothesis for pulmonary cyst formation proposes that cysts in BHD arise from defects in cell–cell adhesion, leading to repeated respiration-induced physical stretch-induced stress and, over time, expansion of alveolar spaces particularly in vulnerable regions of lung (Kennedy et al., 20........ Read more »
Hoshika, Y., Takahashi, F., Togo, S., Hashimoto, M., Nara, T., Kobayashi, T., Nurwidya, F., Kataoka, H., Kurihara, M., Kobayashi, E.... (2016) Haploinsufficiency of the gene leads to impaired functions of lung fibroblasts in patients with Birt–Hogg–Dubé syndrome . Physiological Reports, 4(21). DOI: 10.14814/phy2.13025
by Piter Kehoma Boll A flatworm again, at last! Not a land planarian, but a flatworm nonetheless. If there is a group of flatworms that may put land planarians in second plan regarding beauty, those are the polyclads. Living in … Continue reading →... Read more »
"The overall CD [coeliac disease or celiac disease depending on where you live] prevalence was 2.62%, which is statistically significant higher to that reported in the Italian paediatric population... If replicated, these data suggest the importance of regular screening for CD in young patients with ASD [autism spectrum disorder]."Those were some of the findings/conclusions reported in the paper by Sara Calderoni and colleagues  (open-access) and with them, some ........ Read more »
Calderoni, S., Santocchi, E., Del Bianco, T., Brunori, E., Caponi, L., Paolicchi, A., Fulceri, F., Prosperi, M., Narzisi, A., Cosenza, A.... (2016) Serological screening for Celiac Disease in 382 pre-schoolers with Autism Spectrum Disorder. Italian Journal of Pediatrics, 42(1). DOI: 10.1186/s13052-016-0308-x
"After adjustment for several confounders, longer duration of breastfeeding was independently associated with better cognitive development and with fewer autistic traits."So said the paper by Olivier Boucher and colleagues  communicating findings based on the examination of data from "the INMA Project, a Spanish multicenter birth-cohort study" (an initiative that has cropped up on this blog before).Including over 1300 children who were subject to a battery of psychometric and behavioural asse........ Read more »
Boucher O, Julvez J, Guxens M, Arranz E, Ibarluzea J, Sánchez de Miguel M, Fernández-Somoano A, Tardon A, Rebagliato M, Garcia-Esteban R.... (2016) Association between breastfeeding duration and cognitive development, autistic traits and ADHD symptoms: a multicenter study in Spain. Pediatric research. PMID: 27846197
by Lg_on_the_move in Language on the Move
Many people around the world dream of learning English. The pursuit of English is rarely only, or even predominantly, about language learning: it’s...... Read more »
Cho, J. (2015) Sleepless in Seoul: Neoliberalism, English fever, and linguistic insecurity among Korean interpreters. Multilingua. DOI: 10.1515/multi-2013-0047
Children’s beliefs about animal welfare and sentience are linked to their own experiences with animals.Surprisingly little is known about children’s beliefs and knowledge about animals. Yet this information could help to improve humane education programs for children. Two recent studies begin to fill this gap, with recommendations for how humane education is taught.We know from previous research that even very young children like animals, and that children with pets are more likely to attrib........ Read more »
Hawkins, R., & Williams, J. (2016) Children’s Beliefs about Animal Minds (Child-BAM): Associations with Positive and Negative Child–Animal Interactions. Anthrozoös, 29(3), 503-519. DOI: 10.1080/08927936.2016.1189749
Muldoon, J., Williams, J., & Lawrence, A. (2016) Exploring Children’s Perspectives on the Welfare Needs of Pet Animals. Anthrozoös, 29(3), 357-375. DOI: 10.1080/08927936.2016.1181359
Apolipoprotein A5 gene (APOA5) is one of the genes implicated in contributing to a predisposition for hypertriacylglycerolaemia (HTG), a complex polygenic pathology that is highly influenced by environment. Hypertriacylglycerolaemia is characterized by having high circulating triacylglycerol levels and is a significant risk factor for cardiovascular disease and atherosclerosis. This genetic predisposition has an inherited component (based on polymorphisms) as well as an acquired component regu........ Read more »
Oliva, I., Guardiola, M., Vallve, J., Ibarretxe, D., Plana, N., Masana, L., Monk, D., & Ribalta, J. (2016) APOA5 genetic and epigenetic variability jointly regulate circulating triacylglycerol levels. Clinical Science, 130(22), 2053-2059. DOI: 10.1042/CS20160433
Shoulder taping is associated with early activation of scapular muscles; however, this only resulted in a minimal effect on shoulder kinematics. ... Read more »
Leong, H., Ng, G., & Fu, S. (2016) Effects of scapular taping on the activity onset of scapular muscles and the scapular kinematics in volleyball players with rotator cuff tendinopathy. Journal of Science and Medicine in Sport. DOI: 10.1016/j.jsams.2016.10.013
"This study does not support the hypothesis that MPH [methylphenidate] increases risk of incident psychotic events. It does indicate an increased risk of psychotic events before the first prescription of MPH, which may be because of an association between psychotic events and the behavioural and attentional symptoms that led to psychiatric assessment and initiation of MPH treatment."The results published by Man and colleagues  (open-access) sit right with me. I say that on the basis........ Read more »
Man, K., Coghill, D., Chan, E., Lau, W., Hollis, C., Liddle, E., Banaschewski, T., McCarthy, S., Neubert, A., Sayal, K.... (2016) Methylphenidate and the risk of psychotic disorders and hallucinations in children and adolescents in a large health system. Translational Psychiatry, 6(11). DOI: 10.1038/tp.2016.216
The Sun is an active star. It manifests not only in everybody’s well-known Sun spots with the related 11-year cycle. This activity manifests not only as the well-known sun spot phenomenon with a related 11-year cycle, but also in flares, coronal mass ejections (CMEs), and solar energetic particle (SEP) events. Thus, [...]... Read more »
Gottfried Mann. (2016) Energetic electrons generated during solar flares. Journal of Plasma Physics. info:/
Note: We are rebooting our “Life in the Lab” series, which features interviews of interns and visitors. This post is by our inaugural OMA Visiting Fellow Rosa Fernández García, who spent a month with us earlier this year. You can follow Rosa on Twitter at @Rosamygale. —Christophe
Please introduce yourself and your research interests.
I received my bachelor’s degree in Biology (major in Zoology) at Complutense University in Madrid, Spain. I got my master’s and PhD at the s........ Read more »
Fernández R, Laumer CE, Vahtera V, Libro S, Kaluziak S, Sharma PP, Pérez-Porro AR, Edgecombe GD, & Giribet G. (2014) Evaluating topological conflict in centipede phylogeny using transcriptomic data sets. Molecular biology and evolution, 31(6), 1500-13. PMID: 24674821
Fernández, R., Hormiga, G., & Giribet, G. (2014) Phylogenomic Analysis of Spiders Reveals Nonmonophyly of Orb Weavers. Current Biology, 24(15), 1772-1777. DOI: 10.1016/j.cub.2014.06.035
Fernández R, & Giribet G. (2015) Unnoticed in the tropics: phylogenomic resolution of the poorly known arachnid order Ricinulei (Arachnida). Royal Society open science, 2(6), 150065. PMID: 26543583
Novo M, Fernández R, Andrade SC, Marchán DF, Cunha L, & Díaz Cosín DJ. (2016) Phylogenomic analyses of a Mediterranean earthworm family (Annelida: Hormogastridae). Molecular phylogenetics and evolution, 94(Pt B), 473-8. PMID: 26522608
Fernández R, Edgecombe GD, & Giribet G. (2016) Exploring Phylogenetic Relationships within Myriapoda and the Effects of Matrix Composition and Occupancy on Phylogenomic Reconstruction. Systematic biology, 65(5), 871-89. PMID: 27162151
Sharma, P., Fernandez, R., Esposito, L., Gonzalez-Santillan, E., & Monod, L. (2015) Phylogenomic resolution of scorpions reveals multilevel discordance with morphological phylogenetic signal. Proceedings of the Royal Society B: Biological Sciences, 282(1804), 20142953-20142953. DOI: 10.1098/rspb.2014.2953
Rosa Fernandez, Prashant Sharma, Ana LM Tourinho, & Gonzalo Giribet. (2016) The Opiliones Tree of Life: shedding light on harvestmen relationships through transcriptomics. BioRxiv. DOI: 10.1101/077594
I'm gonna be fairly brief today and draw your attention to yet another systematic review and meta-analysis this time looking at how "probiotic supplementation can have a positive effect on mood and psychological symptoms such as depression and anxiety."  Probiotics by the way, include a variety of bacteria and related lifeforms that are thought to confer some health advantage.The review/re-analysis by Jennifer McKean and colleagues found 7 studies on this topic in the peer-reviewed resea........ Read more »
McKean J, Naug H, Nikbakht E, Amiet B, & Colson N. (2016) Probiotics and Subclinical Psychological Symptoms in Healthy Participants: A Systematic Review and Meta-Analysis. Journal of alternative and complementary medicine (New York, N.Y.). PMID: 27841940
Franz Joseph Gall (1758-1828), a founding father of phrenology
Phrenology was the pseudoscience of identifying a person's character and mental abilities on the basis of skull morphology (“bumps on the head”). The enterprise was based on four assumptions (Gross, 2009):
intellectual abilities and personality traits are differentially developed in each individual
these abilities and traits
... Read more »
Eling, P., Finger, S., & Whitaker, H. (2016) On the Origins of Organology: Franz Joseph Gall and a Girl Named Bianchi. Cortex. DOI: 10.1016/j.cortex.2016.11.010
Parkinson's disease (PD) is a progressive neurodegerative disorder estimated to affect 7 to 10 million individual worldwide.The primary mechanism for Parkinson's disease is a reduction in the neurotransmitter dopamine in the midbrain region of the substantia nigra highlighted in red in the figure.PD impairs motor and cognitive functions and leads to significant decline in psychosocial functioning.Drugs for PD can be effective in reversing and slowing the progression of the illness. However, resp........ Read more »
Lauzé M, Daneault JF, & Duval C. (2016) The Effects of Physical Activity in Parkinson's Disease: A Review. Journal of Parkinson's disease, 6(4), 685-698. PMID: 27567884
"CRP [C-reactive protein] concentrations are increased in bipolar disorder regardless of mood state, but are higher during mania than in depression and euthymia, suggesting an increased inflammatory burden in mania."So said the systematic review and meta-analysis published by Brisa Fernandes and colleagues  who surveyed the peer-reviewed literature on the topic of "measured serum and plasma CRP concentrations in adult patients with bipolar disorder (as defined by DSM-IV-TR) and........ Read more »
Fernandes BS, Steiner J, Molendijk ML, Dodd S, Nardin P, Gonçalves CA, Jacka F, Köhler CA, Karmakar C, Carvalho AF.... (2016) C-reactive protein concentrations across the mood spectrum in bipolar disorder: a systematic review and meta-analysis. The lancet. Psychiatry. PMID: 27838212
Are the eyes the windows to intelligence? In an interesting paper, Georgia psychologists Jason S. Tsukahara and colleagues report that there's a positive correlation between pupil size and cognitive ability.
It's well known that our pupil size varies over time due to changes in both emotional state and cognitive 'effort'. As Tsukahara et al. put it
Starting in the 1960s it became apparent to psychologists that the size of the pupil is related to more than just the amount of light enterin... Read more »
Tsukahara JS, Harrison TL, & Engle RW. (2016) The relationship between baseline pupil size and intelligence. Cognitive psychology, 109-123. PMID: 27821254
The results published by Robert Joseph and colleagues  provide some blogging fodder today, observing that as part of the ELGAN (Extremely Low Gestational Age Newborns) Research Study, gestational age might matter when it comes to offspring risk of autism spectrum disorder (ASD).Gestational age is a measure of how far along a pregnancy is but in the context of the Joseph study refers to premature birth or those "born at least 3 months early." Researchers included data for nearly 1000........ Read more »
Joseph, R., Korzeniewski, S., Allred, E., O’Shea, T., Heeren, T., Frazier, J., Ware, J., Hirtz, D., Leviton, A., & Kuban, K. (2016) Extremely low gestational age and very low birth weight for gestational age are risk factors for ASD in a large cohort study of 10-year-old children born at 23-27 weeks gestation. American Journal of Obstetrics and Gynecology. DOI: 10.1016/j.ajog.2016.11.1009
It does not come as a surprise that background music in a café helps create the ambience and affects how much customers enjoy sipping their cappuccinos. But recent research suggests that the choice of lyrics can even impact the social behavior of customers. The researcher Nicolas Ruth and his colleagues from the University of Würzburg (Bavaria, Germany) assembled a playlist of 18 songs with pro-social lyrics which they had curated by surveying 74 participants in an online questionnaire as to w........ Read more »
Ruth, N. (2016) "Heal the World": A field experiment on the effects of music with prosocial lyrics on prosocial behavior. Psychology of Music. DOI: 10.1177/0305735616652226
I don’t mean to brag, but I’ve got irritable bowel syndrome, says a character of a sitcom.
Irritable bowel syndrome used to be a rare condition, but became a problem of epidemic proportions, until the disease "came out of the closet". Then Internet searches and doctor visits started to dwindle down and less than halved compared to earlier decades.
Is IBS no longer a problem? [...]... Read more »
Camilleri M, Oduyebo I, & Halawi H. (2016) Chemical and molecular factors in irritable bowel syndrome: current knowledge, challenges, and unanswered questions. American journal of physiology. Gastrointestinal and liver physiology, 311(5). PMID: 27609770
Lacy BE, Patel H, Guérin A, Dea K, Scopel JL, Alaghband R, Wu EQ, & Mody R. (2016) Variation in Care for Patients with Irritable Bowel Syndrome in the United States. PloS one, 11(4). PMID: 27116612
Dorn, S., & Meek, P. (2013) Su1024 Ambulatory Care for Irritable Bowel Syndrome in the United States, 1993-2010. Gastroenterology, 144(5). DOI: 10.1016/S0016-5085(13)61392-X
Lackner, J., Brasel, A., Quigley, B., Keefer, L., Krasner, S., Powell, C., Katz, L., & Sitrin, M. (2010) The ties that bind: perceived social support, stress, and IBS in severely affected patients. Neurogastroenterology , 22(8), 893-900. DOI: 10.1111/j.1365-2982.2010.01516.x
The Zoo Hypothesis Hello? Anybody out there in the starry skies? If there are extra-terrestrial civilizations, why haven’t we heard from them yet? The sheer magnitude of the universe with its billions upon billions of stars has led many to suggest that life must have arisen more than once in the cosmos. Some have gone […]... Read more »
de Magalhães, J. (2016) A direct communication proposal to test the Zoo Hypothesis. Space Policy. DOI: 10.1016/j.spacepol.2016.06.001
Do you write about peer-reviewed research in your blog? Use ResearchBlogging.org to make it easy for your readers — and others from around the world — to find your serious posts about academic research.
If you don't have a blog, you can still use our site to learn about fascinating developments in cutting-edge research from around the world.
Research Blogging is powered by SMG Technology.
To learn more, visit seedmediagroup.com.