MedicalResearch.com Interview with: Dr. Alison Thorburn Ph.D. Department of Immunology Monash University Victoria, Australia Medical Research: What is the background for this study? Dr. Thorburn: Asthma is a highly prevalent disease in the Western World. The prevailing explanation for this … Continue reading →
The post High Fiber Diet During Pregnancy May Reduce Risk of Childhood Asthma appeared first on MedicalResearch.com Medical Research Interviews and News.
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Dr. Alison Thorburn Ph.D. (2015) High Fiber Diet During Pregnancy May Reduce Risk of Childhood Asthma. MedicalResearch.com. info:/
Parental age at offspring conception/birth in relation to offspring autism risk has been a recurrent theme in autism research circles for quite a few years now. I've covered it more than once on this blog (see here for example) and the various suggestions that advancing parental age in particular, might elevate the risk of offspring autism.Set in this context, the paper by Sven Sandin and colleagues  (open-access) (a name not unfamiliar to this blog) adds to the research evidence based on the........ Read more »
Sandin S, Schendel D, Magnusson P, Hultman C, Surén P, Susser E, Grønborg T, Gissler M, Gunnes N, Gross R.... (2015) Autism risk associated with parental age and with increasing difference in age between the parents. Molecular psychiatry. PMID: 26055426
When psychologists scan the brains of a group of people, they usually do so in the hope that the findings will generalise more widely. For example, if they find that there are correlations between localised brain shrinkage and mental performance in a group of healthy older participants, they will usually infer that such correlations apply in healthy older people more generally. But there's an important problem with this logic (one that applies to other fields of psychology): what if the people w........ Read more »
Ganguli, M., Lee, C., Hughes, T., Snitz, B., Jakubcak, J., Duara, R., & Chang, C. (2014) Who wants a free brain scan? Assessing and correcting for recruitment biases in a population-based sMRI pilot study. Brain Imaging and Behavior, 9(2), 204-212. DOI: 10.1007/s11682-014-9297-9
Children no longer obey their parents; every man wants to write a book and the end of the world is evidently approaching. So said a clay tablet inscribed almost 5 thousand years ago. But the world still stands, although we do go through golden and dark ages and societies rise and fall. Technology's golden age is now. or so we hope. How are current generations influenced by it and how will they shape the future world? Even as they age, Baby Boomers embrace emerging technologies such as smartphone........ Read more »
Putre L. (2013) The march of the Millenials. Your hospital staff in 2025: the same, only different. Hospitals , 87(9), 38. PMID: 24260968
Costanza, D., Badger, J., Fraser, R., Severt, J., & Gade, P. (2012) Generational Differences in Work-Related Attitudes: A Meta-analysis. Journal of Business and Psychology, 27(4), 375-394. DOI: 10.1007/s10869-012-9259-4
Of 1283 survey respondents, only 27% of athletes reported using mental skills such as goal setting, positive self-talk, imagery, and relaxation. Of the 249 respondents who used mental skills 72% reported they felt it helped expedite their recovery process.... Read more »
Arvinen-Barrow M, Clement D, Hamson-Utley JJ, Zakrajsek RA, Lee SM, Kamphoff C, Lintunen T, Hemmings B, & Martin SB. (2015) Athletes' use of mental skills during sport injury rehabilitation. Journal of Sport Rehabilitation, 24(2), 189-97. PMID: 25996227
Scientists have developed a new way to grow hematite as an electrode in solar water-splitting devices to greatly improve efficiency!... Read more »
Jang, J., Du, C., Ye, Y., Lin, Y., Yao, X., Thorne, J., Liu, E., McMahon, G., Zhu, J., Javey, A.... (2015) Enabling unassisted solar water splitting by iron oxide and silicon. Nature Communications, 7447. DOI: 10.1038/ncomms8447
by Gegentuul Baioud in Language on the Move
Last week when I saw in my friends’ Wechat group an advertisement for delicately made Mongolian yurts, I thought of an article I had read earlier written by Mongolian scholar Naran Bilik. In his paper about urbanized Mongolians Bilik writes: … Continue reading →... Read more »
Brox, T. (2015) Tibetan minzu market: the intersection of ethnicity and commodity . Asian Ethnicity, 1-21. DOI: 10.1080/14631369.2015.1013175
Most of the fancy words used by life science folks are dry but effective. However, every once in a while a researcher will discover a new gene or small molecule and decide to gift it with a fun and creative name.The bacterium Photorhabdus luminescens has a gene called makes caterpillars floppy (mcf), which encodes a toxin that causes caterpillars to go all floppy like before it kills them. P. luminescens is a super interesting little bug. It hangs out in the gut of a worm that infects insects, h........ Read more »
Caro I, & Low JA. (2010) The role of the hedgehog signaling pathway in the development of basal cell carcinoma and opportunities for treatment. Clinical cancer research : an official journal of the American Association for Cancer Research, 16(13), 3335-9. PMID: 20439455
Daborn, P., Waterfield, N., Silva, C., Au, C., Sharma, S., & ffrench-Constant, R. (2002) A single Photorhabdus gene, makes caterpillars floppy (mcf), allows Escherichia coli to persist within and kill insects. Proceedings of the National Academy of Sciences, 99(16), 10742-10747. DOI: 10.1073/pnas.102068099
MedicalResearch.com Interview with: Andreas Vigelsø PhD, research assistant University of Copenhagen Faculty of Health Sciences Center for Healthy Aging Dept. of Biomedical Sciences Copenhagen Denmark Medical Research: What is the background for this study? Response: According to the UN, the … Continue reading →
The post Both Young and Old Lose Muscle Strength After Short Term Inactivity appeared first on MedicalResearch.com Medical Research Interviews and News.
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Andreas Vigelsø PhD, research assistant, & University of Copenhagen. (2015) Both Young and Old Lose Muscle Strength After Short Term Inactivity. MedicalResearch.com. info:/
Previous studies have shown that men find female faces more attractive when the women are ovulating, but the visual clues that allow this are unclear. Now, new research investigating whether it might be to do with subtle changes in skin colour has shown that women’s faces do increase in redness during ovulation, but the levels of change are just under the detectable range of the human eye.... Read more »
Hannah Rowland, & Robert Burriss. (2015) Women’s faces get redder at ovulation, but human eyes can’t pick up on it. PLOS ONE. info:/
This is the second post reviewing recent novel trials for the treatment of bipolar disorder.Again, for my sources I am using are clinicaltrials.gov and PubMed.Clicking on the study title will take you to the clinicaltrials.gov site for more detailed protocol information.Allopurinol Maintenance Study for Bipolar DisorderThis completed study examined the effect of 300 to 600 mg per day of allopurinol on mania prevention. Allopurinol is a drug used primarily for the treatment of gout or kidney ston........ Read more »
Jahangard, L., Soroush, S., Haghighi, M., Ghaleiha, A., Bajoghli, H., Holsboer-Trachsler, E., & Brand, S. (2013) In a double-blind, randomized and placebo-controlled trial, adjuvant allopurinol improved symptoms of mania in in-patients suffering from bipolar disorder. Pharmacopsychiatry, 46(06). DOI: 10.1055/s-0033-1353345
Lauder S, Chester A, Castle D, Dodd S, Gliddon E, Berk L, Chamberlain J, Klein B, Gilbert M, Austin DW.... (2015) A randomized head to head trial of MoodSwings.net.au: an Internet based self-help program for bipolar disorder. Journal of affective disorders, 13-21. PMID: 25282145
Rapinesi C, Bersani FS, Kotzalidis GD, Imperatori C, Del Casale A, Di Pietro S, Ferri VR, Serata D, Raccah RN, Zangen A.... (2015) Maintenance Deep Transcranial Magnetic Stimulation Sessions are Associated with Reduced Depressive Relapses in Patients with Unipolar or Bipolar Depression. Frontiers in neurology, 16. PMID: 25709596
Here’s more evidence that fish oil supplementation and antioxidants might be beneficial for at least some people facing Alzheimer’s disease. A new report describes the findings of a very small study in which people with mild clinical impairment, such as those in the very early stages of the disease, saw clearance of the hallmark amyloid-beta protein and reduced inflammation in neurological tissues. Although the findings involved just 12 patients over the course of 4 to 17 months, the finding........ Read more »
Fiala M, Halder RC, Sagong B, Ross O, Sayre J, Porter V, & Bredesen DE. (2015) ω-3 Supplementation increases amyloid-β phagocytosis and resolvin D1 in patients with minor cognitive impairment. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. PMID: 25805829
Image: Photograph by Jack Wilgus ofa daguerreotype of Phineas Gagein the collection of Jack and Beverly Wilgus.It's a remarkable, mythical tale with lashings of gore – no wonder it's a favourite of psychology students the world over. I'm talking about Phineas Gage, the nineteenth century railway worker who somehow survived the passing of a three-foot long tamping iron through the front of his brain and out the top of his head. What happened to him next?If you turn to many of the leading introd........ Read more »
Griggs, R. (2015) Coverage of the Phineas Gage Story in Introductory Psychology Textbooks: Was Gage No Longer Gage?. Teaching of Psychology, 42(3), 195-202. DOI: 10.1177/0098628315587614
MedicalResearch.com Interview with: Jennifer A. Sumner, Ph.D. Columbia University Mailman School of Public Health New York, NY 10032 Medical Research: What is the background for this study? What are the main findings? Dr. Sumner: Cardiovascular disease, which includes conditions like … Continue reading →
The post Women With PTSD At Higher Risk For Heart Disease appeared first on MedicalResearch.com Medical Research Interviews and News.
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Jennifer A. Sumner, Ph.D., Columbia University Mailman School of Public Health, & New York, NY 10032. (2015) Women With PTSD At Higher Risk For Heart Disease. MedicalResearch.com. info:/
With gravitational lensing, researchers have located population III stars in far galaxies.... Read more »
Rydberg, C., Zackrisson, E., Zitrin, A., Guaita, L., Melinder, J., Asadi, S., Gonzalez, J., Östlin, G., & Ström, T. (2015) A SEARCH FOR POPULATION III GALAXIES IN CLASH. I. SINGLY IMAGED CANDIDATES AT HIGH REDSHIFT. The Astrophysical Journal, 804(1), 13. DOI: 10.1088/0004-637X/804/1/13
A new paper from a group of American neurologists makes the case that Hitler suffered from Parkinson's disease for much of his life, and that some of his most fateful decisions were influenced by the neurological disorder.
The article is by Raghav Gupta and colleagues and it appears in World Neurosurgery - a journal with an interesting political history of its own.
Gupta et al. note that
The possibility of Hitler suffering from Parkinson's has long been the subject of debate... [a res... Read more »
Gupta R, Kim C, Agarwal N, Lieber B, & Monaco EA 3rd. (2015) Understanding the Influence of Parkinson's Disease on Adolf Hitler's Decision-Making during World War II. World neurosurgery. PMID: 26093359
A quote to begin: "Overall, the manuscript supports the idea that ASD [autism spectrum disorder] results from gene–environment interactions and that in the presence of a genetic predisposition to ASD, diet can make a large difference in the expression of the condition."The manuscript in question was by Antonio Currais and colleagues  reporting some rather interesting results based on the 'dangermouse' that is the BTBR mouse model of autism. Researchers from the Salk Inst........ Read more »
Currais A, Farrokhi C, Dargusch R, Goujon-Svrzic M, & Maher P. (2015) Dietary glycemic index modulates the behavioral and biochemical abnormalities associated with autism spectrum disorder. Molecular psychiatry. PMID: 26055422
MedicalResearch.com Interview with: Hui Zhu, MD, ScD Section Chief, Urology Section Louis Stokes Cleveland Veterans Affairs Medical Center and Staff, Glickman Urological and Kidney Institute, Cleveland Clinic Foundation Cleveland, Ohio MedicalResearch: Tell me a little bit about the impetus for … Continue reading →
The post Active Surveillance Utilization For Prostate Cancer Remains Low appeared first on MedicalResearch.com Medical Research Interviews and News.
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Hui Zhu, MD, ScD, Section Chief, Urology Section, & Louis Stokes Cleveland Veterans Affairs Medical Center. (2015) Active Surveillance Utilization For Prostate Cancer Remains Low. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Timothy P. Padera, PhD Edwin L. Steele Laboratories Department of Radiation Oncology MGH Cancer Center, Massachusetts General Hospital and Harvard Medical School Boston, Massachusetts 02114 MedicalResearch: What is the background for this study? What are the main … Continue reading →
The post Lymph Node Cancer Metastases Do Not Require Growth of New Blood Vessels appeared first on MedicalResearch.com Medical Research Interviews and News.
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Timothy P. Padera, PhD, Edwin L. Steele Laboratories, & Department of Radiation Oncology. (2015) Lymph Node Cancer Metastases Do Not Require Growth of New Blood Vessels. MedicalResearch.com. info:/
A look at living with disease close at hand, using a couple different papers. Living with Risk.... Read more »
Foxman EF, Storer JA, Fitzgerald ME, Wasik BR, Hou L, Zhao H, Turner PE, Pyle AM, & Iwasaki A. (2015) Temperature-dependent innate defense against the common cold virus limits viral replication at warm temperature in mouse airway cells. Proceedings of the National Academy of Sciences of the United States of America, 112(3), 827-32. PMID: 25561542
Martincorena I, Roshan A, Gerstung M, Ellis P, Van Loo P, McLaren S, Wedge DC, Fullam A, Alexandrov LB, Tubio JM.... (2015) Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin. Science (New York, N.Y.), 348(6237), 880-6. PMID: 25999502
Cherry, J., Liu, B., Frost, J., Lemere, C., Williams, J., Olschowka, J., & O’Banion, M. (2012) Galactic Cosmic Radiation Leads to Cognitive Impairment and Increased Aβ Plaque Accumulation in a Mouse Model of Alzheimer’s Disease. PLoS ONE, 7(12). DOI: 10.1371/journal.pone.0053275
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