Post List

  • April 20, 2015
  • 01:58 PM
  • 4 views

Assay May Determine Which Triple Negative Breast Cancers Respond To Platinum Chemotherapy

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Steven Jay Isakoff, MD, PhD Hematology/Oncology Department of Medicine Massachusetts General Hospital Medical Research: What is the background for this study? What are the main findings? Dr. Isakoff: Metastatic triple negative breast cancer remains a challenging clinical … Continue reading →
The post Assay May Determine Which Triple Negative Breast Cancers Respond To Platinum Chemotherapy app........ Read more »

MedicalResearch.com Interview with:, & Steven Jay Isakoff, MD, PhD. (2015) Assay May Determine Which Triple Negative Breast Cancers Respond To Platinum Chemotherapy. MedicalResearch.com. info:/

  • April 20, 2015
  • 12:33 PM
  • 4 views

Some Periodontal Bacteria May Be Cancer-Promoting

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Xiaodan Mai MBBS University at Buffalo, The State University of New York Buffalo, NY MedicalResearch: What is the background for this study? What are the main findings? Response: Periodontal disease is a condition that is highly prevalent … Continue reading →
The post Some Periodontal Bacteria May Be Cancer-Promoting appeared first on MedicalResearch.com Medical Research Interviews and News.
........ Read more »

Xiaodan Mai MBBS, University at Buffalo, The State University of New York, & Buffalo, NY. (2015) Some Periodontal Bacteria May Be Cancer-Promoting. MedicalResearch.com. info:/

  • April 20, 2015
  • 12:16 PM
  • 3 views

Prolonging Duration Of Nightly Fast May Reduce Breast Cancer Risk

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Catherine Marinac Doctoral Candidate UC San Diego/San Diego State University Joint-Doctoral Program in Public Health La Jolla, CA 92093 MedicalResearch: What is the background for this study? What are the main findings? Response: The dietary advice for … Continue reading →
The post Prolonging Duration Of Nightly Fast May Reduce Breast Cancer Risk appeared first on MedicalResearch.com Medical ........ Read more »

MedicalResearch.com Interview with: Catherine Marinac. (2015) Prolonging Duration Of Nightly Fast May Reduce Breast Cancer Risk. MedicalResearch.com. info:/

  • April 20, 2015
  • 11:39 AM
  • 54 views

The Human Epigenome Roadmap

by Daniel Koboldt in Massgenomics

Aside from the occasional somatic mutation, the genome of every cell in an individual’s body is largely preserved. Yet different types of cells (and tissues, and organs) are incredibly diverse. The majority of that specialization is governed by epigenetic changes — histone modifications, DNA accessibility, and methylation — that influence when and how genes are expressed. […]... Read more »

Roadmap Epigenomics Consortium, Kundaje A, Meuleman W, Ernst J, Bilenky M, Yen A, Heravi-Moussavi A, Kheradpour P, Zhang Z, Wang J.... (2015) Integrative analysis of 111 reference human epigenomes. Nature, 518(7539), 317-30. PMID: 25693563  

  • April 20, 2015
  • 11:32 AM
  • 61 views

ADHD and Autism Overlap: Adult Twin Study

by William Yates, M.D. in Brain Posts

Clinical studies show high rates of ADHD in adults with autism or autism spectrum disorder (ASD). These studies have estimated the prevalence of ADHD in adults with ASD at between 28 and 44% of individuals. The prevalence of ADHD in the adult general population without ASD is estimated at 2.5%.Given the overlap between these two developmental disorders, it makes sense to examine genetic factors that might contribute to co-occurrence.TJC Polderman along with colleagues from the Netherlands, ........ Read more »

  • April 20, 2015
  • 09:45 AM
  • 48 views

Aphasia factors vs. subtypes

by Dan Mirman in Minding the Brain

One of the interesting things (to me anyway) that came out of our recent factor analysis project (Mirman et al., 2015, in press; see Part 1 and Part 2) is a way of reconsidering aphasia types in terms of psycholinguistic factors rather than the traditional clinical aphasia subtypes. The traditional aphasia subtyping approach is to use a diagnostic test like the Western Aphasia Battery or the Boston Diagnostic Aphasia Examination to assign an individual with aphasia to one of several subtype cate........ Read more »

Mirman, D., Chen, Q., Zhang, Y., Wang, Z., Faseyitan, O.K., Coslett, H.B., & Schwartz, M.F. (2015) Neural Organization of Spoken Language Revealed by Lesion-Symptom Mapping. Nature Communications, 6(6762), 1-9. info:/

  • April 20, 2015
  • 04:51 AM
  • 60 views

Tics are common in adults with autism

by Paul Whiteley in Questioning Answers

The title of this post comes from a quote included in the paper by Ursula Kahl and colleagues [1] based on their study of the "phenomenology and characteristics" of tics in adults diagnosed with an autism spectrum disorder (ASD) compared with a small control group of adults with Gilles de la Tourette syndrome (GTS). A tic by the way, is a "sudden, fast, repeated movement or sound."This is not the first time that tics have been examined with the autism spectrum in mind. The paper from C........ Read more »

Kahl, U., Schunke, O., Schöttle, D., David, N., Brandt, V., Bäumer, T., Roessner, V., Münchau, A., & Ganos, C. (2015) Tic Phenomenology and Tic Awareness in Adults With Autism. Movement Disorders Clinical Practice. DOI: 10.1002/mdc3.12154  

  • April 20, 2015
  • 04:47 AM
  • 8 views

Autistic children's sensory experiences, in their own words

by BPS Research Digest in BPS Research Digest

Children diagnosed with autism often have distinctive sensory experiences, such as being ultra sensitive to noise, or finding enjoyment in repeated, unusual sensory stimulation. However, much of what we know about these experiences comes from the testimony of parents, researchers and clinicians. Now Anne Kirby and her colleagues have published the first report of autistic children's sensory experiences, based on these children's own accounts. As the authors say, "children's voices are still rare........ Read more »

  • April 20, 2015
  • 04:35 AM
  • 54 views

Males Are Here To Stay: Sex Enhances Egg Production And Colony Fitness

by beredim in Strange Animals

To us humans, it seems extremely unnatural that other animals can reproduce without having sex. Yet with the passing of time, evolution has endowed females of several species of amphibians, insects, reptiles and fish the ability to asexually produce offsprings without "help" from males.



Now, researchers at the Okinawa Institute of Science and Technology Graduate University (OIST) say that in ... Read more »

  • April 20, 2015
  • 12:05 AM
  • 46 views

Delayed Onset of Concussion Symptoms may Predict Delayed Recovery in Young Athletes

by Kathleen Cummer in Sports Medicine Research (SMR): In the Lab & In the Field

Delayed onset of symptoms after sport-related concussion puts young athletes at a 20.7 times greater risk for postconcussion syndrome... Read more »

  • April 19, 2015
  • 05:29 PM
  • 83 views

Accepting pain – or are we measuring something else?

by Bronwyn Thompson in Healthskills: Skills for Healthy Living

Acceptance is defined in Acceptance and Commitment Therapy (ACT) as “a willingness to remain in contact with and to actively experience particular private experiences (Hayes, Jacobson, Follette, Dougher, 1994) (eds): Acceptance and Change: Content and Context in Psychotherapy. Reno, Context Press, 1994), and from this Lance McCracken and colleagues developed the Chronic Pain Acceptance Questionnaire. This measure has two dimensions: willingness to experience pain and engaging in values-dir........ Read more »

  • April 19, 2015
  • 03:23 PM
  • 48 views

Aphid flight trends follow climate change: a fifty years long analysis!

by Mauro Mandrioli in The aphid room

I started to find now on different crops near Modena the first aphid populations… it is not too early neither too late… in respect to the last years. However, it seems that in Italy we started to have aphids earlier on our plants in the last years. Interestingly, a recent papers clearly assessed this trend … Continue reading Aphid flight trends follow climate change: a fifty years long analysis!... Read more »

  • April 19, 2015
  • 01:49 PM
  • 66 views

Botox makes unnerving journey into our nervous system

by Dr. Jekyll in Lunatic Laboratories

New research might bring a frown to even the most heavily botoxed faces, with scientists finding how some of the potent toxin used for cosmetic surgery escapes into the central nervous system. Researchers have shown how Botox – also known as Botulinum neurotoxin serotype A – is transported via our nerves back to the central nervous system.... Read more »

Wang, T., Martin, S., Papadopulos, A., Harper, C., Mavlyutov, T., Niranjan, D., Glass, N., Cooper-White, J., Sibarita, J., Choquet, D.... (2015) Control of Autophagosome Axonal Retrograde Flux by Presynaptic Activity Unveiled Using Botulinum Neurotoxin Type A. Journal of Neuroscience, 35(15), 6179-6194. DOI: 10.1523/JNEUROSCI.3757-14.2015  

  • April 18, 2015
  • 07:24 PM
  • 89 views

Introducing Lassa-VSV, a hybrid virus that kills brain tumours

by Betty Zou in Eat, Read, Science

In a paper published this past week in the Journal of Virology, researchers at Yale University and Harvard University tried to overcome the neurotoxicity of VSV by engineering a hybrid virus. The researchers wanted to know if swapping out the G protein of VSV with the G protein from another virus would lessen the harmful effects of VSV on the brain while maintaining its tumour-killing abilities.... Read more »

Wollmann G, Drokhlyansky E, Cepko C, & van den Pol AN. (2015) Lassa-VSV chimeric virus safely destroys brain tumors. Journal of virology. PMID: 25878115  

  • April 18, 2015
  • 02:14 PM
  • 85 views

Kids with ADHD must squirm to learn

by Dr. Jekyll in Lunatic Laboratories

For decades, frustrated parents and teachers have barked at fidgety children with ADHD to “Sit still and concentrate!” But new research shows that if you want ADHD kids to learn, you have to let them squirm. The foot-tapping, leg-swinging and chair-scooting movements of children with attention-deficit/hyperactivity disorder are actually vital to how they remember information and work out complex cognitive tasks.... Read more »

  • April 18, 2015
  • 08:00 AM
  • 85 views

Is There Signal in the fMRI Noise?

by Neuroskeptic in Neuroskeptic_Discover

A new paper in Neuroimage suggests that methods for removing head motion and physiological noise from fMRI data might be inadvertently excluding real signal as well.

The authors, Molly G. Bright and Kevin Murphy of Cardiff, studied the technique called nuisance regression. It's a popular approach for removing fMRI noise. Noise reduction is important because factors such as head movement, the heart beat, and breathing, can contaminate the fMRI signal and lead to biased results. Nuisance regres... Read more »

  • April 18, 2015
  • 05:22 AM
  • 83 views

Autistic traits in adult-onset psychiatric disorders?

by Paul Whiteley in Questioning Answers

"To conclude, the presentation of ALTs [autistic-like traits/symptoms] at the sub-threshold or threshold level may be closely associated with BPD [bipolar disorder] and SZ [schizophrenia]."That was the conclusion reached in the paper by Junko Matsuo and colleagues [1] (open-access here) based on their analysis of nearly 300 adults aged between 25-59 years including those diagnosed with "MDD [major depressive disorder], n=125; bipolar disorder, n=56; schizophrenia,&n........ Read more »

Matsuo J, Kamio Y, Takahashi H, Ota M, Teraishi T, Hori H, Nagashima A, Takei R, Higuchi T, Motohashi N.... (2015) Autistic-Like Traits in Adult Patients with Mood Disorders and Schizophrenia. PloS one, 10(4). PMID: 25838109  

  • April 18, 2015
  • 04:45 AM
  • 81 views

Major Advance in Artificial Photosynthesis

by Perikis Livas in Chilon

A potentially game-changing breakthrough in artificial photosynthesis has been achieved with the development of a system that can capture carbon dioxide emissions before they are vented into the atmosphere and then, powered by solar energy, convert that carbon dioxide into valuable chemical products, including biodegradable plastics, pharmaceutical drugs and even liquid fuels.... Read more »

  • April 17, 2015
  • 09:59 PM
  • 6 views

5% of Patients Account For 47% VA Health Care Costs

by Marie Benz in MedicalResearch.com

MedicalResearch.com Medical Research Interviews and News
MedicalResearch.com Interview with: Donna Zulman MD MS Center for Innovation to Implementation, VA Palo Alto Health Care System, Menlo Park Division of General Medical Disciplines, Stanford University, Stanford California, USA Medical Research: What is the background for this study? Dr. … Continue reading →
The post 5% of Patients Account For 47% VA Health Care Costs appeared first on MedicalResearch.com Medical Research Interv........ Read more »

MedicalResearch.com Interview with: Donna Zulman MD MS. (2015) 5% of Patients Account For 47% VA Health Care Costs. MedicalResearch.com. info:/

  • April 17, 2015
  • 07:47 PM
  • 99 views

Study links brain anatomy, academic achievement, and family income

by Dr. Jekyll in Lunatic Laboratories

Many years of research have shown that for students from lower-income families, standardized test scores and other measures of academic success tend to lag behind those of wealthier students. Well now a new study offers another dimension to this so-called “achievement gap”After imaging the brains of high- and low-income students, they found that the higher-income students had thicker brain cortex in areas associated with visual perception and knowledge accumulation.... Read more »

Allyson Mackey et al. (2015) Students’ Family Income Linked With Brain Anatomy, Academic Achievement. Psychological Science. info:/

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