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A blog about science and science journalism; good, bad, and bogus.
Michael Slezak
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by Michael Slezak in Good, Bad, and Bogus
If you wrote to the organising committee of a scientific conference saying that you have a theory that there is a person in everyone’s bum and if you massage it in the...... Read more »
McLachlan JC. (2010) Integrative medicine and the point of credulity. BMJ (Clinical research ed.). PMID: 21147748
by Michael Slezak in Good, Bad, and Bogus
Yeah — I didn’t think this was a belief that anyone held either. But apparently it’s Danish urban folklore that you can become drunk by submerging your feet in an...... Read more »
Christian Stevns Hansen, Louise Holmsgaard Færch, Peter Lommer Kristensen. (2010) Testing the validity of the Danish urban myth that alcohol can be absorbed through feet: open labelled self experimental study. The British Medical Journal. info:/10.1136/bmj.c6812
by Michael Slezak in Good, Bad, and Bogus
The ethics of conducting medical trials can be tricky. There is always the risk someone could be exposed to a drug that is dangerous, or they could miss out on...... Read more »
Stein CM, & Ray WA. (2010) The ethics of placebo in studies with fracture end points in osteoporosis. The New England journal of medicine, 363(14), 1367. PMID: 20879888
Rosen CJ, & Khosla S. (2010) Placebo-controlled trials in osteoporosis--proceeding with caution. The New England journal of medicine, 363(14), 1365. PMID: 20879887
by Michael Slezak in Good, Bad, and Bogus
It seems that hardly a month goes by without another shocking example of drug companies hiding, manipulating or lying about data in order to mislead consumers about the safety or...... Read more »
Godlee F, & Loder E. (2010) Missing clinical trial data: setting the record straight. BMJ (Clinical research ed.). PMID: 20940217
Eyding, D., Lelgemann, M., Grouven, U., Harter, M., Kromp, M., Kaiser, T., Kerekes, M., Gerken, M., & Wieseler, B. (2010) Reboxetine for acute treatment of major depression: systematic review and meta-analysis of published and unpublished placebo and selective serotonin reuptake inhibitor controlled trials. BMJ, 341(oct12 1). DOI: 10.1136/bmj.c4737
by Michael Slezak in Good, Bad, and Bogus
Should randomised trials be the only type of evidence accepted for rolling out drug treatments?
If so, then two researchers wrote in the Lancet this week that that we face a problem:
The evidence we have might not be the evidence we need, and the evidence that we need may never become available.
They are writing in response [...]... Read more »
Munro, A., & Niblock, P. (2010) Cancer research in the global village. The Lancet. DOI: 10.1016/S0140-6736(10)61022-7
Bang, Y., Van Cutsem, E., Feyereislova, A., Chung, H., Shen, L., Sawaki, A., Lordick, F., Ohtsu, A., Omuro, Y., & Satoh, T. (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. The Lancet. DOI: 10.1016/S0140-6736(10)61121-X
by Michael Slezak in Good, Bad, and Bogus
Is it possible that if you have schizophrenia, smoking marijuana will actually improve your cognitive performance?
Since this blog is often concerned with the relationship between science and its communication, something which has come up once or twice here is the way drug and alcohol research is reported in the media.
Very often, it is reported that [...]... Read more »
Yücel M, Bora E, Lubman DI, Solowij N, Brewer WJ, Cotton SM, Conus P, Takagi MJ, Fornito A, Wood SJ.... (2010) The Impact of Cannabis Use on Cognitive Functioning in Patients With Schizophrenia: A Meta-analysis of Existing Findings and New Data in a First-Episode Sample. Schizophrenia bulletin. PMID: 20660494
Frisher, M., Crome, I., Martino, O., & Croft, P. (2009) Assessing the impact of cannabis use on trends in diagnosed schizophrenia in the United Kingdom from 1996 to 2005. Schizophrenia Research, 113(2-3), 123-128. DOI: 10.1016/j.schres.2009.05.031
by Michael Slezak in Good, Bad, and Bogus
You’ll often see loony zealots refer you to a study showing how effective their preferred treatment is — there usually is some small study supporting the use of almost any treatment.
You’ll also often hear people reply that the study was only small, so shouldn’t be trusted. But why shouldn’t you trust small studies? Sure, they [...]... Read more »
Nüesch E, Trelle S, Reichenbach S, Rutjes AW, Tschannen B, Altman DG, Egger M, & Jüni P. (2010) Small study effects in meta-analyses of osteoarthritis trials: meta-epidemiological study. BMJ. PMID: 20639294
by Michael Slezak in Good, Bad, and Bogus
Reports of a physicist “taking on gravity” have recieved a bit of attention recently, with a New York Times article outlining Erik Verlinde’s idea that gravity is an emergent property of thermodynamics.
I think it’s great that the piece was written — even though apparently it hasn’t excited any physicists since the start of the year. Regardless [...]... Read more »
Erik P. Verlinde. (2010) On the Origin of Gravity and the Laws of Newton. arxiv.org. arXiv: 1001.0785v1
Bertrand Russell. (1912) On the notion of cause. Proceedings of the Aristotelian Society. info:other/
by Michael Slezak in Good, Bad, and Bogus
This is the second part in a series about the myths and realities of alcohol consumption.
I pray thee let me and my fellow have
A hair of the dog that bit us last night—
And bitten were we both to the brain aright
- John Heywood
The idea that alcohol may itself be a cure for alcohol hangovers is [...]... Read more »
Jeffrey G. Wiese, MD; Michael G. Shlipak, MD, MPH; and Warren S. Browner, MD, MPH. (2000) The Alcohol Hangover. Annals of Internal Medicine, 152(12), 897-902. info:/
Verster JC. (2009) The "hair of the dog": a useful hangover remedy or a predictor of future problem drinking?. Current drug abuse reviews, 2(1), 1-4. PMID: 19630732
Wiese JG, Shlipak MG, & Browner WS. (2000) The alcohol hangover. Annals of internal medicine, 132(11), 897-902. PMID: 10836917
by Michael Slezak in Good, Bad, and Bogus
This is the first part of a series that aims to bust some myths about booze.
Hangovers suck and they’re probably best avoided. But once you’ve got one, can you get rid of it? People swear by their favourite hangover cures — insisting that if you just follow their advice, you’ll free yourself of the post-intoxicated state.
Can [...]... Read more »
Verster JC. (2008) The alcohol hangover--a puzzling phenomenon. Alcohol and alcoholism (Oxford, Oxfordshire), 43(2), 124-6. PMID: 18182417
by Michael Slezak in Good, Bad, and Bogus
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Ahead of a landmark study, newspapers all around the world have carried news reports warning of the terrible risk faced by mobile phone users.
The story behind the story is worth a few words. Firstly, the study seems to says opposite to what all these reports claim. Secondly, the study was under embargo until the [...]... Read more »
Elisabeth Cardis. (2010) Brain tumour risk in relation to mobile telephone use: results of the INTERPHONE international case–control study. International Journal of Epidemiology, 1-20. info:/10.1093/ije/dyq079
by Michael Slezak in Good, Bad, and Bogus
I was recently commissioned to write a short news story about a some unpublished research. Should journalists be writing about research that hasn’t undergone peer review?
The research was about the Mpemba effect — where hot water sometimes freezes faster than cold water — and was published online on arXiv. It is quite poorly written but [...]... Read more »
James D. Brownridge. (2010) A search for the Mpemba effect: When hot water freezes faster then cold water. arXiv. arXiv: 1003.3185v1
by Michael Slezak in Good, Bad, and Bogus
A couple of weeks ago there was an interesting exchange in The Guardian between George Monbiot and Nicholas Maxwell, a philosopher of science from University College London. In his piece, Monbiot presents an excellent, if overly pessimistic, analysis of the psychology behind climate change denial. In his response, Maxwell draws on some interesting results from the philosophy [...]... Read more »
Cartwright, Nancy. (2004) Do the laws of physics state the facts?. Readings on the Laws of Nature. info:/
Kitcher, P. (1981) Explanatory Unification. Philosophy of Science, 48(4), 507. DOI: 10.1086/289019
by Michael Slezak in Good, Bad, and Bogus
“Teen Pot Use Linked To Psychoses“, “Teen pot smokers at high risk of mental illness“,”Study finds cannabis use is ‘crazy-making’” are the headlines being produced about some new research that finds a link between cannabis use and psychosis
But are the headlines justified? Well, headlines like this are rarely justified. A more interesting question worth asking [...]... Read more »
Frisher, M., Crome, I., Martino, O., & Croft, P. (2009) Assessing the impact of cannabis use on trends in diagnosed schizophrenia in the United Kingdom from 1996 to 2005. Schizophrenia Research, 113(2-3), 123-128. DOI: 10.1016/j.schres.2009.05.031
McGrath, J., Welham, J., Scott, J., Varghese, D., Degenhardt, L., Hayatbakhsh, M., Alati, R., Williams, G., Bor, W., & Najman, J. (2010) Association Between Cannabis Use and Psychosis-Related Outcomes Using Sibling Pair Analysis in a Cohort of Young Adults. Archives of General Psychiatry. DOI: 10.1001/archgenpsychiatry.2010.6
by Michael Slezak in Good, Bad, and Bogus
“Ok brain. I don’t like you and you don’t like me. Let’s just do this and I can go back to killing you with beer.” - Homer Simpson
A new piece of research has elicited headlines around the world in today’s newspapers such as “Coma patient ‘talks’ with his thoughts” and “Coma victim talks via brain [...]... Read more »
Monti MM, Vanhaudenhuyse A, Coleman MR, Boly M, Pickard JD, Tshibanda L, Owen AM, & Laureys S. (2010) Willful Modulation of Brain Activity in Disorders of Consciousness. The New England journal of medicine. PMID: 20130250
Martin M. Monti, & Audrey Vanhaudenhuyse. (2010) Willful Modulation of Brain Activity in Disorders of Consciousness. The New England Journal of Medicine. info:/10.1056/NEJMoa0905370
by Michael Slezak in Good, Bad, and Bogus
In a previous post which considered some of the bogus science claims made by the Australian TV show Today Tonight, I had a brief look at a few things that fish oil is supposed to treat. It seemed fair to say that counter to the strong claims made by TT, the evidence suggests that fish oil [...]... Read more »
Amminger, G., Schafer, M., Papageorgiou, K., Klier, C., Cotton, S., Harrigan, S., Mackinnon, A., McGorry, P., & Berger, G. (2010) Long-Chain Ω-3 Fatty Acids for Indicated Prevention of Psychotic Disorders: A Randomized, Placebo-Controlled Trial. Archives of General Psychiatry, 67(2), 146-154. DOI: 10.1001/archgenpsychiatry.2009.192
by Michael Slezak in Good, Bad, and Bogus
A little while ago, I wrote a post about an article in Science about the relationship between “objective” measurements of “quality of life” and subjective measurements of “life-satisfaction”. The article found a very high correlation between these measurements leading the authors to claim that there was now “objective verification” of the subjective measurements often used [...]... Read more »
Oswald, A., & Wu, S. (2009) Objective Confirmation of Subjective Measures of Human Well-Being: Evidence from the U.S.A. Science. DOI: 10.1126/science.1180606
Schwarz, N., Strack, F., & Mai, H. (1991) Assimilation and Contrast Effects in Part-Whole Question Sequences: A Conversational Logic Analysis. Public Opinion Quarterly, 55(1), 3. DOI: 10.1086/269239
Norbert Schwarz, & Fritz Strack. (1991) Context Effects in Attitude Surveys: Applying Cognitive Theory to Social Research. European Review of Social Psychology. info:/
Oishi, S. (2003) The contextual and systematic nature of life satisfaction judgments. Journal of Experimental Social Psychology, 39(3), 232-247. DOI: 10.1016/S0022-1031(03)00016-7
Schkade, D., & Kahneman, D. (1998) Does Living in California Make People Happy? A Focusing Illusion in Judgments of Life Satisfaction. Psychological Science, 9(5), 340-346. DOI: 10.1111/1467-9280.00066
by Michael Slezak in Good, Bad, and Bogus
For some time now, there has been a heated debate in Australia about home births. Home birth advocates argue that a woman should have the right to choose how to give birth to her baby and if she chooses to have a home birth, that choice should be supported by providing the her with adequate [...]... Read more »
by Michael Slezak in Good, Bad, and Bogus
... Read more »
by Michael Slezak in Good, Bad, and Bogus
I’ve been reluctant to call bogus on science reporting from shows like Today Tonight or A Current Affair because, well, it’s just too easy. That, and I don’t watch them.
It feels kind of cheap picking on Today Tonight when they feel the necessity to put at the bottom of the idiotic reporting on their website [...]... Read more »
Hagen KB, Byfuglien MG, Falzon L, Olsen SU, & Smedslund G. (2009) Dietary interventions for rheumatoid arthritis. Cochrane database of systematic reviews (Online). PMID: 19160281
Leon, H., Shibata, M., Sivakumaran, S., Dorgan, M., Chatterley, T., & Tsuyuki, R. (2008) Effect of fish oil on arrhythmias and mortality: systematic review. BMJ, 337(dec23 2). DOI: 10.1136/bmj.a2931
Saravanan P, & Davidson NC. (2009) Fish oil and arrhythmias. Pro-arrhythmic effects of fish oils. BMJ (Clinical research ed.). PMID: 19188223
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