14 posts · 7,734 views
We are a science blog that discusses peer-reviewed papers aimed at people who might not be experts in the field. We also interview researchers and discuss science communication in general.
A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.... Read more »
Fujihira H, Masahara-Negishi Y, Tamura M, Huang C, Harada Y, Wakana S, Takakura D, Kawasaki N, Taniguchi N, Kondoh G.... (2017) Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene. PLoS genetics, 13(4). PMID: 28426790
Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant.... Read more »
Selvaraj, M., Ishizaki, T., Valencia, M., Ogawa, S., Dedicova, B., Ogata, T., Yoshiwara, K., Maruyama, K., Kusano, M., Saito, K.... (2017) Overexpression of an galactinol synthase gene improves drought tolerance in transgenic rice and increased grain yield in the field . Plant Biotechnology Journal. DOI: 10.1111/pbi.12731
Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.... Read more »
Kaburagi T, Kizuka Y, Kitazume S, & Taniguchi N. (2016) Inhibitory role of α2,6-sialylation in adipogenesis. The Journal of biological chemistry. PMID: 28031460
Scientists have identified that social memories are stored in the vetral CA1 region of the brain (in mice). After meeting a mouse and forgetting it, the memories can be reactivated optogenetically, indicating that they exist, but cannot be retrieved after time passes... Read more »
iPS cell-derived retinal cells have been successfully transplanted from one money to another without need of immunosuppressant drugs.... Read more »
Sugita S, Iwasaki Y, Makabe K, Kamao H, Mandai M, Shiina T, Ogasawara K, Hirami Y, Kurimoto Y, & Takahashi M. (2016) Successful Transplantation of Retinal Pigment Epithelial Cells from MHC Homozygote iPSCs in MHC-Matched Models. Stem cell reports. PMID: 27641649
Measuring altitude using atomic clocks seems like a crazy idea, but it’s already being done at RIKEN in Japan.... Read more »
Takano, T., Takamoto, M., Ushijima, I., Ohmae, N., Akatsuka, T., Yamaguchi, A., Kuroishi, Y., Munekane, H., Miyahara, B., & Katori, H. (2016) Geopotential measurements with synchronously linked optical lattice clocks. Nature Photonics. DOI: 10.1038/nphoton.2016.159
Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology... Read more »
Takagi, R., Ishimaru, J., Sugawara, A., Toyoshima, K., Ishida, K., Ogawa, M., Sakakibara, K., Asakawa, K., Kashiwakura, A., Oshima, M.... (2016) Bioengineering a 3D integumentary organ system from iPS cells using an in vivo transplantation model. Science Advances, 2(4). DOI: 10.1126/sciadv.1500887
Neuroamanda explains a recent study that showed how top-down signals during NREM sleep affect memory consolidation in mice.... Read more »
Miyamoto, D., Hirai, D., Fung, C., Inutsuka, A., Odagawa, M., Suzuki, T., Boehringer, R., Adaikkan, C., Matsubara, C., Matsuki, N.... (2016) Top-down cortical input during NREM sleep consolidates perceptual memory. Science. DOI: 10.1126/science.aaf0902
I recently spoke with Chief Scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.... Read more »
Sugahara, F., Pascual-Anaya, J., Oisi, Y., Kuraku, S., Aota, S., Adachi, N., Takagi, W., Hirai, T., Sato, N., Murakami, Y.... (2016) Evidence from cyclostomes for complex regionalization of the ancestral vertebrate brain. Nature, 531(7592), 97-100. DOI: 10.1038/nature16518
An interview with Yuko Kiyosue, discussing the 3D images of living cells that gained her and her colleagues a recent award for best paper in Science magazine.... Read more »
Chen BC, Legant WR, Wang K, Shao L, Milkie DE, Davidson MW, Janetopoulos C, Wu XS, Hammer JA 3rd, Liu Z.... (2014) Lattice light-sheet microscopy: imaging molecules to embryos at high spatiotemporal resolution. Science (New York, N.Y.), 346(6208), 1257998. PMID: 25342811
Learn what electrolithoautotrophs are and how the scientists proved that A. ferrooxidans can use electric potential to fuel growth.... Read more »
Ishii, T., Kawaichi, S., Nakagawa, H., Hashimoto, K., & Nakamura, R. (2015) From chemolithoautotrophs to electrolithoautotrophs: CO2 fixation by Fe(II)-oxidizing bacteria coupled with direct uptake of electrons from solid electron sources. Frontiers in Microbiology. DOI: 10.3389/fmicb.2015.00994
Black smokers are deep-sea hydrothermal vents found in the ocean. Now scientists believe that they may host electroecosystems in which the primary producers use electric currents as their energy source.... Read more »
Nakamura, R., Takashima, T., Kato, S., Takai, K., Yamamoto, M., & Hashimoto, K. (2010) Electrical Current Generation across a Black Smoker Chimney. Angewandte Chemie International Edition, 49(42), 7692-7694. DOI: 10.1002/anie.201003311
Amanda Alvarez writes about how neuroscientists are studying consciousness with mathematics.... Read more »
Oizumi M, Tsuchiya N, & Amari SI. (2016) Unified framework for information integration based on information geometry. Proceedings of the National Academy of Sciences of the United States of America, 113(51), 14817-14822. PMID: 27930289
Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.... Read more »
Watabe, M., Arjunan, S., Fukushima, S., Iwamoto, K., Kozuka, J., Matsuoka, S., Shindo, Y., Ueda, M., & Takahashi, K. (2015) A Computational Framework for Bioimaging Simulation. PLOS ONE, 10(7). DOI: 10.1371/journal.pone.0130089
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