9 posts · 5,019 views
Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration Yujing Zhang, Danqing Liu, Xi Chen, Jing Li, Limin Li, Zhen Bian, Fei Sun, Jiuwei Lu, Yuan Yin, Xing Cai, Qi Sun, Kehui Wang, Yi Ba, Qiang Wang, Dongjin Wang, Junwei Yang, Pingsheng Liu, Tao Xu, Qiao Yan, Junfeng Zhang, Ke Zen, and Chen-Yu Zhang Molecular Cell [...]... Read more »
Zhang Y, Liu D, Chen X, Li J, Li L, Bian Z, Sun F, Lu J, Yin Y, Cai X.... (2010) Secreted monocytic miR-150 enhances targeted endothelial cell migration. Molecular cell, 39(1), 133-44. PMID: 20603081
Target RNA–Directed Trimming and Tailing of Small Silencing RNAs Stefan L. Ameres, Michael D. Horwich, Jui-Hung Hung, Jia Xu, Megha Ghildiyal, Zhiping Weng, Phillip D. Zamore Science 328: 1534–1539, 18 June 2010. DOI: 10.1126/science.1187058 This week’s thorough summary and analysis by Anonymous: Like you, Drosophila siRNAs’d prefer an Argonaute; in fact their Argonaute of choice [...]... Read more »
Ameres SL, Horwich MD, Hung JH, Xu J, Ghildiyal M, Weng Z, & Zamore PD. (2010) Target RNA-directed trimming and tailing of small silencing RNAs. Science, 328(5985), 1534-9. PMID: 20558712
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology Laura Poliseno, Leonardo Salmena, Jiangwen Zhang, Brett Carver, William J. Haveman & Pier Paolo Pandolfi Nature 465: 1033–1038, 24 June 2010. doi:10.1038/nature09144 No formal write-up for this week, rather just some points to consider, raised during our journal club discussion: The authors’ probing of [...]... Read more »
Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, & Pandolfi PP. (2010) A coding-independent function of gene and pseudogene mRNAs regulates tumour biology. Nature, 465(7301), 1033-8. PMID: 20577206
Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control Isabel Novoa, Javier Gallego, Pedro G. Ferreira & Raul Mendez Nature Cell Biology 12: 447 – 456, May 2010. doi:10.1038/ncb2046 This week’s lucid summary and analysis by Noah Spies. This is Noah’s second contribution to the blog: A normal eukaryotic messenger RNA is capped, [...]... Read more »
Novoa I, Gallego J, Ferreira PG, & Mendez R. (2010) Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control. Nature cell biology, 12(5), 447-56. PMID: 20364142
Most “Dark Matter” Transcripts Are Associated With Known Genes Harm van Bakel, Corey Nislow, Benjamin J. Blencowe, Timothy R. Hughes PLoS Biology, 8 (5): e1000371, 18 May 2010. doi:10.1371/journal.pbio.1000371 This week’s illuminating summary and analysis by Igor Ulitsky. It’s Igor’s second contribution to the blog: The paper is one of at least five interesting RNA-Seq [...]... Read more »
van Bakel H, Nislow C, Blencowe BJ, & Hughes TR. (2010) Most "dark matter" transcripts are associated with known genes. PLoS biology, 8(5). PMID: 20502517
A dicer-independent miRNA biogenesis pathway that requires Ago catalysis Sihem Cheloufi, Camila O. Dos Santos, Mark M. W. Chong & Gregory J. Hannon Nature, 465: 584–589, 3 June 2010. Nature AOP, 27 April 2010. doi:10.1038/nature09092 This week’s summary and ruminative analysis by Vikram Agarwal. It’s Vikram’s second contribution to the blog: In this article, [...]... Read more »
Cheloufi S, Dos Santos CO, Chong MM, & Hannon GJ. (2010) A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature. PMID: 20424607
Cooperation Between Translating Ribosomes and RNA Polymerase in Transcription Elongation Sergey Proshkin, A. Rachid Rahmouni, Alexander Mironov, Evgeny Nudler Science, Vol. 328. no. 5977: pp. 504 – 508, 23 April 2010. DOI: 10.1126/science.1184939 This week’s smart summary and analysis by Pavan Vaidyanathan: In this paper, the authors propose a mechanism for active physical cooperation between [...]... Read more »
Proshkin S, Rahmouni AR, Mironov A, & Nudler E. (2010) Cooperation between translating ribosomes and RNA polymerase in transcription elongation. Science, 328(5977), 504-8. PMID: 20413502
Caspase-Dependent Conversion of Dicer Ribonuclease into a Death-Promoting Deoxyribonuclease
Akihisa Nakagawa, Yong Shi, Eriko Kage-Nakadai, Shohei Mitani, Ding Xue
Science Express, 11 March 2010.
This week’s methodische summary and analysis–impressively her third contribution to this blog–by Anna Drinnenberg:
In this paper Nakagawa and colleagues describe a new role for Dicer (DCR-1) in the apoptotic pathway of C. elegans. [...]... Read more »
Nakagawa A, Shi Y, Kage-Nakadai E, Mitani S, & Xue D. (2010) Caspase-Dependent Conversion of Dicer Ribonuclease into a Death-Promoting Deoxyribonuclease. Science. PMID: 20223951
Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins
Brian R. McNaughton, James J. Cronican, David B. Thompson and David R. Liu
PNAS 106 (15): 6111-6116, 14 April 2009.
This week’s shrewd summary/analysis–impressively his third contribution to this blog–by David Weinberg:
In their 2009 PNAS paper, David Liu and colleagues demonstrate that a green fluorescent protein [...]... Read more »
McNaughton BR, Cronican JJ, Thompson DB, & Liu DR. (2009) Mammalian cell penetration, siRNA transfection, and DNA transfection by supercharged proteins. Proceedings of the National Academy of Sciences of the United States of America, 106(15), 6111-6. PMID: 19307578
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