I recently read an article in Science entitled “Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions” written by Choudhary et al. The research uses “high-resolution mass spectrometry to identify 3600 lysine acetylation sites on 1750 proteins” and “demonstrate[s] that the regulatory scope of lysine acetylation is broad and comparable with that of other [...]... Read more »
Choudhary, C., Kumar, C., Gnad, F., Nielsen, M., Rehman, M., Walther, T., Olsen, J., & Mann, M. (2009) Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions. Science, 325(5942), 834-840. DOI: 10.1126/science.1175371
So the other day on a political board, actually, I heard about a treatment that may be helping to fight Colony Collapse Disorder (CCD) in bees. It had originally been posted by Treehugger. So the blogs have been abuzz with the news. It seems there is an Israeli company called Beeologics that has developed a product called Remembee which can knock down the IAPV (Israeli acute paralysis virus) that is purported to be one of the contributors to CCD.... Read more »
Maori, E., Paldi, N., Shafir, S., Kalev, H., Tsur, E., Glick, E., & Sela, I. (2009) IAPV, a bee-affecting virus associated with Colony Collapse Disorder can be silenced by dsRNA ingestion. Insect Molecular Biology, 18(1), 55-60. DOI: 10.1111/j.1365-2583.2009.00847.x
Scrolling through some of my regular podcasts the other day I came across this tidbit about bioinformatics growing in New York (among other things, or course!)
It is is a discussion with Dr. Damon Little, a curator of bioinformatics from the New York Botanical Garden. The focus of the discussion is the recent publication of the CBOL Plant Working Group which has settled on the regions that will be used for barcoding plants.... Read more »
CBOL Plant Working Group. (2009) A DNA barcode for land plants. PNAS, 106(31), 12794-12797. info:/10.1073/pnas.0905845106
Singer, G., & Hajibabaei, M. (2009) iBarcode.org: web-based molecular biodiversity analysis. BMC Bioinformatics, 10(Suppl 6). DOI: 10.1186/1471-2105-10-S6-S14
Edgar, R. (2004) MUSCLE: multiple sequence alignment with high accuracy and high throughput. Nucleic Acids Research, 32(5), 1792-1797. DOI: 10.1093/nar/gkh340
The MINT or Molecular Interaction database for examination of protein interaction networks has long been a favorite tool of mine. The regular “flavor” of MINT includes over 100,000 interactions with a focus on experimentally verified protein interaction data. But recently I became aware of the VirusMINT data that is now available as well.... Read more »
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