295 posts · 161,103 views
I received a PhD in analytical chemistry in Sep 2005, completed postdoctoral research in Jun 2007, and taught chemistry survey and organic chemistry from Sep 2009 - May 2010. I am currently a freelance technical science editor. Phased presents science journalism written for a lay audience. My goal is to discuss technical content (from the technical journals) without sacrificing readability. The topical focus is diverse, but tends to focus on chemistry, technology, and cell biology.
Phased
295 posts
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- May 23, 2009
- 03:30 PM
- 701 views
BIO/MEDICAL TECHNOLOGIES: Color-Based Detection of Calcium Ions in Blood Serum
by Michael Long in Phased
Sangyong Jon (Gwangju Institute of Science and Technology,
South Korea) and coworkers have developed a practically-useful
assay for calcium ions, for disease diagnostics purposes.
This news feature was written on May 23, 2009.... Read more »
Kim, S., Park, J. W., Kim, D., Kim, D., Lee, I.-H., & Jon, S. (2009) Bioinspired Colorimetric Detection of Calcium(II) Ions in Serum Using Calsequestrin-Functionalized Gold Nanoparticles. Angewandte Chemie International Edition, 48(23), 4138-4141. DOI: 10.1002/anie.200900071
- May 22, 2009
- 12:00 PM
- 661 views
BIO/MEDICAL TECHNOLOGIES: Improved Synthesis of Chiral Fluoride Molecules
by Michael Long in Phased
Karl Jorgensen (Aarhus University, Denmark) and coworkers
have developed an improved synthetic protocol for a class of
molecules that are otherwise particularly challenging to prepare,
which are of wide-ranging biochemical and pharmaceutical utility.
This news feature was written on May 22, 2009.... Read more »
Jiang, H., Falcicchio, A., Jensen, K. L., Paixão, M. W., Bertelsen, S., & Jørgensen, K. A. (2009) Target-Directed Organocatalysis: A Direct Asymmetric Catalytic Approach to Chiral Propargylic and Allylic Fluorides. Journal of the American Chemical Society, 131(20), 7153-7157. DOI: 10.1021/ja901459z
- May 21, 2009
- 06:30 PM
- 553 views
PUBLIC HEALTH: Combating Copper Toxicity
by Michael Long in Phased
Pascale Delangle (Institute for Nanoscience
and Cryogenics, France) and coworkers have synthesized a
copper-binding molecule that may be useful for treating
disorders related to copper toxicity.
This news feature was written on May 21, 2009.... Read more »
Pujol, A. M., Gateau, C., Lebrun, C., & Delangle, P. (2009) A Cysteine-Based Tripodal Chelator with a High Affinity and Selectivity for Copper(I). Journal of the American Chemical Society, 131(20), 6928-6929. DOI: 10.1021/ja901700a
- May 19, 2009
- 02:00 PM
- 446 views
ECOLOGY: Dry Mangroves are Nonideal for Long-Term Water Treatment
by Michael Long in Phased
Catherine Lovelock (University of Queensland, Australia)
and coworkers have shown that mangroves are ideal wastewater filters
only if they are regularly inundated with tides;
otherwise, wastewater places them at enhanced risk of mortality.
This news feature was written on May 19, 2009.... Read more »
Lovelock, C. E., Ball, M. C., Martin, K. C., & Feller, I. C. (2009) Nutrient Enrichment Increases Mortality of Mangroves. PLoS ONE, 4(5). DOI: 10.1371/journal.pone.0005600
- May 18, 2009
- 05:00 PM
- 655 views
BIO/MEDICAL TECHNOLOGIES: Degradable High-Affinity Delivery Vehicles for Gene Therapy
by Michael Long in Phased
David Smith (University of York, United Kingdom)
and coworkers have synthesized polymers that form strong
chemical bonds with DNA, yet degrade over time, which enhances
their utility as possible DNA delivery vehicles for gene therapy.
This news feature was written on May 18, 2009.... Read more »
Welsh, D. J., Jones, S. P., & Smith, D. K. (2009) “On-Off” Multivalent Recognition: Degradable Dendrons for Temporary High-Affinity DNA Binding. Angewandte Chemie International Edition, 48(22), 4047-4051. DOI: 10.1002/anie.200900401
- May 17, 2009
- 03:00 PM
- 593 views
ECOLOGY: Helping Bumble Bees Adapt to an Increasingly Urban World
by Michael Long in Phased
Karin Ahrne (Swedish University of Agricultural Sciences)
and coworkers have explored the factors governing the
diversity, abundance, species composition, and uniform
pollination capacity of bumble bees, which is important
for ensuring the continuation of their critically important
role in pollination.
This news feature was written on May 17, 2009.... Read more »
Ahrné, K., Bengtsson, J., & Elmqvist, T. (2009) Bumble Bees (Bombus spp) along a Gradient of Increasing Urbanization. PLoS ONE, 4(5). DOI: 10.1371/journal.pone.0005574
- May 16, 2009
- 02:30 PM
- 595 views
BIO/MEDICAL TECHNOLOGIES: A Rapid Fluorescence-Based Thiol Quantitation Assay
by Michael Long in Phased
Zhen Xi (Nankai University, China) and coworkers
have developed a rapid assay for thiol molecules, which are
implicated in many healthy and diseased cellular functions.
This news feature was written on May 16, 2009.... Read more »
Yi, L., Li, H., Sun, L., Liu, L., Zhang, C., & Xi, Z. (2009) A Highly Sensitive Fluorescence Probe for Fast Thiol-Quantification Assay of Glutathione Reductase. Angewandte Chemie International Edition, 48(22), 4034-4037. DOI: 10.1002/anie.200805693
- May 15, 2009
- 12:30 PM
- 634 views
PUBLIC HEALTH: A Fluorescence-Based Sensor for Lead
by Michael Long in Phased
Partha Basu (Duquesne University, Pennsylvania)
and coworkers have synthesized a molecule that enables lead ion
detection at concentrations below that permitted by
environmental regulations.
This news feature was written on May 15, 2009.... Read more »
Marbella, L., Serli-Mitasev, B., & Basu, P. (2009) Development of a Fluorescent Pb2 Sensor . Angewandte Chemie International Edition, 48(22), 3996-3998. DOI: 10.1002/anie.200806297
- May 14, 2009
- 07:30 PM
- 859 views
ALTERNATIVE ENERGY: Converting Biomass into a Stable Fuel
by Michael Long in Phased
Yuan Kou (Peking University, China), Johannes Lercher
(Technische Universitat Munchen, Germany), and coworkers
have synthesized stable carbon-based fuels from
renewable resources.
This news feature was written on May 14, 2009.... Read more »
Zhao, C., Kou, Y., Lemonidou, A. A., Li, X., & Lercher, J. A. (2009) Highly Selective Catalytic Conversion of Phenolic Bio-Oil to Alkanes. Angewandte Chemie International Edition, 48(22), 3987-3990. DOI: 10.1002/anie.200900404
- May 12, 2009
- 07:30 PM
- 842 views
ASTRONOMY: Towards Detecting Photosynthesis on Other Worlds
by Michael Long in Phased
William Sparks (Space Telescope
Science Institute, Maryland) and coworkers have probed the
feasibility of detecting photosynthesis through
astronomical observations, aiding the long-term search for
extraterrestrial life.
This news feature was written on May 12, 2009.... Read more »
Sparks, W. B., Hough, J., Germer, T. A., Chen, F., DasSarma, S., DasSarma, P., Robb, F. T., Manset, N., Kolokolova, L., Reid, N.... (2009) Detection of circular polarization in light scattered from photosynthetic microbes. Proceedings of the National Academy of Sciences, 106(19), 7816-7821. DOI: 10.1073/pnas.0810215106
- May 11, 2009
- 01:00 PM
- 564 views
NEUROSCIENCE: Nitric Oxide Modulates the Sense of Smell
by Michael Long in Phased
Christian Wetzel (Ruhr-Universitat Bochum, Germany)
and coworkers have shown that the highly reactive small molecule
nitric oxide plays a role in the sense of smell in adult mice.
This news feature was written on May 11, 2009.... Read more »
Brunert, D., Kurtenbach, S., Isik, S., Benecke, H., Gisselmann, G., Schuhmann, W., Hatt, H., & Wetzel, C. H. (2009) Odorant-Dependent Generation of Nitric Oxide in Mammalian Olfactory Sensory Neurons. PLoS ONE, 4(5). DOI: 10.1371/journal.pone.0005499
- May 10, 2009
- 04:00 PM
- 519 views
NEGLECTED DISEASES: Australia's Adaptation to Water Scarcity May Spread Disease
by Michael Long in Phased
Nigel Beebe (University of Queensland, Australia)
and coworkers have shown that Dengue fever may make a comeback
in Australia, enabled by the nation's adaptation to water scarcity.
This news feature was written on May 10, 2009.... Read more »
Beebe, N. W., Cooper, R. D., Mottram, P., & Sweeney, A. W. (2009) Australia's Dengue Risk Driven by Human Adaptation to Climate Change. PLoS Neglected Tropical Diseases, 3(5). DOI: 10.1371/journal.pntd.0000429
- May 8, 2009
- 07:00 PM
- 790 views
NEUROSCIENCE: Selectively Imaging Alzheimer's-Related Protein Aggregates
by Michael Long in Phased
Itaru Hamachi (Kyoto University, Japan) and coworkers
have imaged neurofibrillary tangles, in preference to senile plaques,
in brain tissue samples, with a cheap synthetic fluorescent molecule.
This news feature was written on May 8, 2009.... Read more »
Ojida, A., Sakamoto, T., Inoue, M.-a., Fujishima, S.-h., Lippens, G., & Hamachi, I. (2009) Fluorescent BODIPY-Based Zn(II) Complex as a Molecular Probe for Selective Detection of Neurofibrillary Tangles in the Brains of Alzheimer’s Disease Patients. Journal of the American Chemical Society, 131(18), 6543-6548. DOI: 10.1021/ja9008369
- May 8, 2009
- 02:30 PM
- 652 views
PUBLIC HEALTH: Rapid Live Bacterial Diagnostics
by Michael Long in Phased
A group of scientists from Taiwan, lead by Chi-Hung Lin,
have rapidly identified and screened living bacteria for
antibiotic resistance, using surface enhanced Raman scattering.
This news feature was written on May 8, 2009.... Read more »
Liu, T.-T., Lin, Y.-H., Hung, C.-S, Liu, T.-J., Chen, Y., Huang, Y.-C., Tsai, T.-H., Wang, H.-H., Wang, D.-W., Wang, J.-K.... (2009) A High Speed Detection Platform Based on Surface-Enhanced Raman Scattering for Monitoring Antibiotic-Induced Chemical Changes in Bacteria Cell Wall. PLoS ONE, 4(5). DOI: 10.1371/journal.pone.0005470
- May 7, 2009
- 02:00 PM
- 637 views
ENVIRONMENTAL REMEDIATION: On-Location Nitrite and Nitrate Pollutant Detection
by Michael Long in Phased
Chad Mirkin (Northwestern University) and coworkers
have developed an assay for nitrite and nitrate pollutants
that is useful for environmental monitoring in remote locations.
This news feature was written on May 7, 2009.... Read more »
Daniel, W. L., Han, M. S., Lee, J.-S., & Mirkin, C. A. (2009) Colorimetric Nitrite and Nitrate Detection with Gold Nanoparticle Probes and Kinetic End Points. Journal of the American Chemical Society, 131(18), 6362-6363. DOI: 10.1021/ja901609k
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