Michael Long

295 posts · 161,323 views

I received a PhD in analytical chemistry in Sep 2005, completed postdoctoral research in Jun 2007, and taught chemistry survey and organic chemistry from Sep 2009 - May 2010. I am currently a freelance technical science editor. Phased presents science journalism written for a lay audience. My goal is to discuss technical content (from the technical journals) without sacrificing readability. The topical focus is diverse, but tends to focus on chemistry, technology, and cell biology.

Phased
295 posts

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  • October 28, 2010
  • 04:43 PM
  • 316 views

Do Not Cut Funding for Mosquito Surveillance

by Michael Long in Phased

Gonzalo Vazquez-Prokopec (Emory University, United States) and coworkers show that reducing the budget of the United States Centers for Disease Control and Prevention vector-borne disease research and surveillance will cost far more money than it saves.... Read more »

Vazquez-Prokopec, G., Chaves, L., Ritchie, S., Davis, J., & Kitron, U. (2010) Unforeseen Costs of Cutting Mosquito Surveillance Budgets. PLoS Neglected Tropical Diseases, 4(10). DOI: 10.1371/journal.pntd.0000858  

  • October 26, 2010
  • 01:43 PM
  • 346 views

The Competitive Advantage of Vibrio cholerae

by Michael Long in Phased

Stefan Pukatzki (University of Alberta, Canada) and coworkers have found that the bacterium which causes cholera attacks other bacteria common to the human stomach and intestines. This finding may help scientists treat and vanquish cholera outbreaks.... Read more »

MacIntyre, D. L., Miyata, S. T., Kitaoka, M., & Pukatzki, S. (2010) The Vibrio cholerae type VI secretion system displays antimicrobial properties. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1012931107  

  • October 25, 2010
  • 07:38 PM
  • 617 views

Finding Parameters for Cancer Progression and other Complex Biological Models

by Michael Long in Phased

Diego Fernandez Slezak (Buenos Aires University, Argentina), Gustavo Stolovitzky (IBM), and coworkers show that a mathematical "best fit" to a complex biological model may be biologically implausible.... Read more »

  • October 22, 2010
  • 06:22 PM
  • 531 views

Industry vs the Leading Medical Journal: Rejection or Fear?

by Michael Long in Phased

Elizabeth Wager (Sideview, United Kingdom) and coworkers show that after requiring independent statistical analysis in academia prior to publication, the Journal of the American Medical Association has been publishing fewer studies financed by industry.... Read more »

  • October 22, 2010
  • 01:13 PM
  • 567 views

The State of Confined Water in the Ribosome Exit Tunnel

by Michael Long in Phased

Vijay Pande (Stanford University, United States) and coworkers have used computer simulations to show that water confined within the ribosome exit tunnel has unique properties, which may explain certain aspects of protein synthesis, and provide insight into how certain antibiotics work.... Read more »

Lucent, D., Snow, C. D., Aitken, C. E., & Pande, V. S. (2010) Non-Bulk-Like Solvent Behavior in the Ribosome Exit Tunnel. PLoS Computational Biology, 6(10). DOI: 10.1371/journal.pcbi.1000963  

  • October 21, 2010
  • 08:35 PM
  • 356 views

International Stock-Brokers: Greedy or Illogical?

by Michael Long in Phased

The ongoing global financial crisis has prompted many to question why it happened. A recent study by Markus Knauff (Justus Liebig University Giessen, Germany) and coworkers investigates the possible role of stock-brokers' irrational behavior in the international meltdown. This news feature was written on October 21, 2010.... Read more »

  • October 20, 2010
  • 11:55 AM
  • 538 views

Structural Contributors to Selective Drug-Protein Binding

by Michael Long in Phased

Are there any chemical features which need to be incorporated into an effective drug molecule? If so, what are they? Paul Clemons, Stuart Schreiber (Harvard University and Massachusetts Institute of Technology, United States), and coworkers have answered these questions on a fundamental level, although more pieces to the puzzle will undoubtedly be uncovered in the future. This news feature was written on October 20, 2010.... Read more »

Clemons, P. A., Bodycombe, N. E., Carrinski, H. A., Wilson, J. A., Shamji, A. F., Wagner, B. K., Koehler, A. N., & Schreiber, S. L. (2010) Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1012741107  

  • October 17, 2010
  • 05:00 PM
  • 378 views

New Insights into When and Why Bacteria Assemble into Biofilms

by Michael Long in Phased

Chuanwu Xi and Jianfeng Wu (University of Michigan, United States) have found that pathogenic bacteria form dense protective aggregates (biofilms) in response to a physiological warning of their presence. This news feature was written on October 17, 2010.... Read more »

  • October 13, 2010
  • 08:57 PM
  • 324 views

Chip-Based Malaria Diagnosis

by Michael Long in Phased

Masatoshi Kataoka (National Institute of Advanced Industrial Science and Technology, Japan) and coworkers have developed technology for fast, cheap, reliable, and sensitive malaria diagnosis. This news feature was written on October 13, 2010.... Read more »

  • October 13, 2010
  • 03:23 PM
  • 316 views

Breaking Through the Hype of Genomic Medicine

by Michael Long in Phased

Wayne Hall (University of Queensland, Australia) and coworkers argue that genetic screening is generally not ready for clinical use, and gets in the way of more effective medical and preventive care. This news feature was written on October 13, 2010.... Read more »

  • October 12, 2010
  • 09:40 AM
  • 427 views

Towards an Improved Treatment for Gluten Intolerance

by Michael Long in Phased

Eva Helmerhorst (Boston University, United States) and coworkers have found that microbes native to the human mouth degrade gliaden, providing hope that gluten intolerance can be countered other than through a strict dietary regimen. This news feature was written on October 12, 2010.... Read more »

  • October 11, 2010
  • 04:50 PM
  • 527 views

Will Global Warming Continue Even After Greenhouse Gas Removal?

by Michael Long in Phased

Computer simulations by Susan Solomon (National Oceanic and Atmospheric Administration, United States) and coworkers suggest that heat trapped deep with the ocean, and only slowly released, will enable a continuation of global warming long after greenhouse gases have been removed from the atmosphere; longer warming will result the longer we wait to stop greenhouse gas emissions. This news feature was written on October 11, 2010.... Read more »

Susan Solomon,, John S. Daniel,, Todd J. Sanford,, Daniel M. Murphy,, Gian-Kasper Plattner,, Reto Knutti,, & Pierre Friedlingstein. (2010) Persistence of climate changes due to a range of greenhouse gases. Proceedings of the National Academy of Sciences. info:/10.1073/pnas.1006282107

  • October 10, 2010
  • 06:15 PM
  • 514 views

Isolating G-quadruplex Nucleic Acids from Human Cells

by Michael Long in Phased

Raphael Rodriguez, Shankar Balasubramanian (University of Cambridge, United Kingdom), and coworkers have isolated DNA, in a specific type of folding arrangement important to intracellular physiology, from human cells. This news feature was written on October 10, 2010.... Read more »

Müller, S., Kumari, S., Rodriguez, R., & Balasubramanian, S. (2010) Small-molecule-mediated G-quadruplex isolation from human cells. Nature Chemistry. DOI: 10.1038/NCHEM.842  

  • October 8, 2010
  • 03:05 PM
  • 437 views

Towards a Conclusive Test of Termite Eradication

by Michael Long in Phased

Why would anyone collect thousands of individual pieces of termite poo? If you're Michael Haverty (University of California Berkeley, United States) or one of his coworkers, you need them to develop an analytical protocol for determining the success of termite eradication. This news feature was written on October 8, 2010.... Read more »

  • October 7, 2010
  • 09:45 PM
  • 374 views

Unique Strains of Yersinia pestis Caused the Black Death

by Michael Long in Phased

Barbara Bramanti (Johannes Gutenberg University, Germany) and coworkers present conclusive biochemical (DNA and protein) evidence that Yersinia pestis, of multiple and possibly extinct lineages, was responsible for the Black Death of medieval Europe. This news feature was written on October 7, 2010.... Read more »

Haensch, S., Bianucci, R., Signoli, M., Rajerison, M., Schultz, M., Kacki, S., Vermunt, M., Weston, D. A., Hurst, D., Achtman, M.... (2010) Distinct Clones of Yersinia pestis Caused the Black Death. PLoS Pathogens, 6(10). DOI: 10.1371/journal.ppat.1001134  

  • October 6, 2010
  • 03:55 PM
  • 281 views

Is it Easy to be an Urban New York Ant?

by Michael Long in Phased

Marko Pecarevic (Columbia University, United States; and State Institute for Nature Protection, Croatia) and coworkers have found that three ant species overwhelmingly dominate heavily urbanized environments in New York City, with implications in natural adaptation to an increasingly urban world. This news feature was written on October 6, 2010.... Read more »

  • October 5, 2010
  • 08:50 PM
  • 511 views

A Lack of Energy May Increase the Size of Human Civilization

by Michael Long in Phased

John DeLong (Yale University, United States) and coworkers present a paradoxical finding, namely that a lack of available energy supplies will enable the human population to keep on growing, rather than stabilize, in the coming decades. This news feature was written on October 5, 2010.... Read more »

  • October 5, 2010
  • 12:00 PM
  • 574 views

An ATP Synthesis Puzzle Answered via Macromolecular Crowding

by Michael Long in Phased

Martin Gruebele, Margaret Cheung (University of Illinois and University of Houston, both in the United States) and coworkers have found that macromolecular crowding may explain a mystery of energy production in living cells. This news feature was written on October 5, 2010.... Read more »

Dhar, A., Samiotakis, A., Ebbinghaus, S., Nienhaus, L., Homouz, D., Gruebele, M., & Cheung, M. S. (2010) Structure, function, and folding of phosphoglycerate kinase are strongly perturbed by macromolecular crowding. Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1006760107  

  • October 3, 2010
  • 04:05 PM
  • 481 views

Selectively Unleashing Cytotoxic Nanoparticles

by Michael Long in Phased

Vincent Rotello (University of Massachusetts Amherst, United States) and coworkers have delivered nanoparticles to cancer cells, and once there, unleashed cytotoxicity via the drug molecule 1-adamantylamine. This news feature was written on October 3, 2010.... Read more »

  • October 1, 2010
  • 07:35 PM
  • 371 views

Grunting During a Tennis Shot May Provide a Competitive Advantage

by Michael Long in Phased

Scott Sinnett (University of Hawaii, United States) and Alan Kingstone (University of British Columbia, Canada) have scientifically tested whether or not a controversial tennis practice is distracting to the opponent. This news feature was written on October 1, 2010.... Read more »

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