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  • August 4, 2015
  • 04:34 PM
  • 14 views

Preventing addiction relapse by erasing drug-associated memories

by Dr. Jekyll in Lunatic Laboratories

Recovering addicts often grapple with the ghosts of their addiction–memories that tempt them to relapse even after rehabilitation and months, or even years, of drug-free living. Now, scientists from the Florida campus of The Scripps Research Institute (TSRI) have made a discovery that brings them closer to a new therapy based on selectively erasing these dangerous and tenacious drug-associated memories.... Read more »

  • August 4, 2015
  • 12:40 PM
  • 7 views

Stem cells: From pluripotency to totipotency

by Dr. Jekyll in Lunatic Laboratories

While it is already possible to obtain in vitro pluripotent cells (ie, cells capable of generating all tissues of an embryo) from any cell type, researchers from Maria-Elena Torres-Padilla’s team have pushed the limits of science even further. They managed to obtain totipotent cells with the same characteristics as those of the earliest embryonic stages and with even more interesting properties.... Read more »

Ishiuchi, T., Enriquez-Gasca, R., Mizutani, E., Bošković, A., Ziegler-Birling, C., Rodriguez-Terrones, D., Wakayama, T., Vaquerizas, J., & Torres-Padilla, M. (2015) Early embryonic-like cells are induced by downregulating replication-dependent chromatin assembly. Nature Structural . DOI: 10.1038/nsmb.3066  

  • August 4, 2015
  • 10:21 AM
  • 10 views

Monkeys Try to Hide Illicit Hookups

by Elizabeth Preston in Inkfish



Just how much monkey business is there in monkey sex? In groups with alpha males, monkeys lower on the totem pole may have to sneak around to mate. How well they conceal their activities can shed light on the cognitive powers of primates.

Macaques are monkeys that live in troops with complex social hierarchies. High-ranking males may have dibs on mating with all the females in the group. But females give non-alpha males a chance too, and some studies have found that these hookups happen m........ Read more »

Overduin-de Vries, A., Spruijt, B., de Vries, H., & Sterck, E. (2015) Tactical deception to hide sexual behaviour: macaques use distance, not visibility. Behavioral Ecology and Sociobiology, 69(8), 1333-1342. DOI: 10.1007/s00265-015-1946-5  

  • August 4, 2015
  • 02:53 AM
  • 17 views

Anti-NMDA-receptor encephalitis and autism: research ascendancy

by Paul Whiteley in Questioning Answers

The paper by Reza Kiani and colleagues [1] (open-access available here) detailing the presence of anti-N-methyl-d-aspartate (NMDA) receptor encephalitis in two people "with autism and intellectual disability presenting with neuropsychiatric symptoms of catatonia and neuroleptic malignant syndrome" caught my eye recently.Having previously talked about anti-NMDA-receptor encephalitis and autism in a previous blog post (see here) back in 2013 with the emphasis on a possible link to 'autis........ Read more »

  • August 3, 2015
  • 12:50 PM
  • 37 views

New approach for making vaccines for deadly diseases

by Dr. Jekyll in Lunatic Laboratories

Researchers have devised an entirely new approach to vaccines – creating immunity without vaccination. The team has demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen-based vaccination. Importantly, this approach, termed DMAb, was rapid, protecting animals within a week of administration.... Read more »

Flingai, S., Plummer, E., Patel, A., Shresta, S., Mendoza, J., Broderick, K., Sardesai, N., Muthumani, K., & Weiner, D. (2015) Protection against dengue disease by synthetic nucleic acid antibody prophylaxis/immunotherapy. Scientific Reports, 12616. DOI: 10.1038/srep12616  

  • August 3, 2015
  • 11:00 AM
  • 31 views

Nature Neuroscience paper: “Oscillatory dynamics coordinating human frontal networks in support of goal maintenance”

by Bradley Voytek in Oscillatory Thoughts 2.0

Phew! One of my post-doc papers is finally out in Nature Neuroscience, “Oscillatory dynamics coordinating human frontal networks in support of goal maintenance” (link). (Parenthetical: if this kind of thing interests you, feel free to drop me an email and/or drop by my lab’s posters at SfN (PDF)!) I can’t begin to express, within the constraints of my literary ability, […]... Read more »

Voytek B, Kayser AS, Badre D, Fegen D, Chang EF, Crone NE, Parvizi J, Knight RT, & D'Esposito M. (2015) Oscillatory dynamics coordinating human frontal networks in support of goal maintenance. Nature neuroscience. PMID: 26214371  

  • August 3, 2015
  • 07:02 AM
  • 34 views

Simple Jury Persuasion: Combatting distrust of science  

by Doug Keene in The Jury Room

The art of persuasion is often complex and diverse, but today’s study also shows how it can be simple and elegant. Here’s a surprisingly easy way to diminish the automatic, knee-jerk and distrusting reaction to scientific findings. Tell your listeners about scientific consensus. Today’s researchers call consensus a “gateway belief” that results in the ability […]

Related posts:
Simple Jury Persuasion: Educating jurors about science may have no effect
Simple Jury Persuasion: The........ Read more »

  • August 3, 2015
  • 05:25 AM
  • 40 views

The smell of fish boosts our reasoning skills

by BPS Research Digest in BPS Research Digest

The nose is an early warning system, urging us to look closer at what we are planning to put in our mouths. But it’s not just alerting us to questionable food. Past research using economic games has shown that when we’re suspicious of a smell, this emotion can spill into social situations, affecting how trusting we are towards others. Now a new study shows that even without the involvement of other people to trust or distrust, smell can make us suspicious of ideas and concepts – and this a........ Read more »

  • August 3, 2015
  • 02:34 AM
  • 46 views

Screening for autism in young children: 6 questions to ask

by Paul Whiteley in Questioning Answers

Question 1: Does your child ever point with their index finger to ask for something?Question 2: Is your child able to imitate you or your actions, for example if you pull a face?Question 3: Does your child ever use pretend play, for example to talk on a phone or take care of a doll?Question 4: Does your child look at something across a room when you point to it?Question 5: Does your child understand what people say?Question 6: Does your child ever bring an object to you to show you something?The........ Read more »

  • August 2, 2015
  • 01:29 PM
  • 60 views

Perfectionism linked to burnout at work, school and sports

by Dr. Jekyll in Lunatic Laboratories

Concerns about perfectionism can sabotage success at work, school or on the playing field, leading to stress, burnout and potential health problems, according to new research. In the first meta-analysis of the relationship between perfectionism and burnout, researchers analyzed the findings from 43 previous studies conducted over the past 20 years. It turns out perfectionism isn’t all bad.... Read more »

  • August 2, 2015
  • 09:54 AM
  • 47 views

A Close Look at the Connectivity of a Single Brain

by Neuroskeptic in Neuroskeptic_Discover

In a new paper just out in Neuron, researchers Timothy Laumann and colleagues present an in-depth analysis of the functional connectivity of a single human brain.



The brain in question belongs to neuroscientist Russ Poldrack, and he's one of the authors of the paper. Poldrack was fMRI scanned a total of 84 times over a period of 532 days. The goal of this intense scanning schedule was to provide a detailed analysis of the functional connectivity of an individual brain.

Previous studies... Read more »

Laumann TO, Gordon EM, Adeyemo B, Snyder AZ, Joo SJ, Chen MY, Gilmore AW, McDermott KB, Nelson SM, Dosenbach NU.... (2015) Functional System and Areal Organization of a Highly Sampled Individual Human Brain. Neuron. PMID: 26212711  

  • August 2, 2015
  • 09:25 AM
  • 29 views

Motion to repudiate Mr. Jeffrey Beall’s classist attack on SciELO

by SciELO in SciELO in Perspective

By the Brazilian Forum of Public Health Journals Editors and the Associação Brasileira de Saúde Coletiva (Abrasco, Brazilian Public Health Association) … Read More →... Read more »

  • August 2, 2015
  • 08:31 AM
  • 59 views

Blood Pressure Dippers May React Differently to Morning Blood Pressure Surge

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Prof. Sante D. Pierdomenico Associate Professor of Internal Medicine University “Gabriele d’Annunzio” Chieti-Pescara – Italy Medical Research: What is the background for this study? What are the main findings? Dr. Pierdomenico: Though a peak incidence of cardiovascular … Continue reading →
The post Blood Pressure Dippers May React Differently to Morning Blood Pressure Surge appeared first on MedicalResearch.com Medical Resea........ Read more »

Prof. Sante D. Pierdomenico. (2015) Blood Pressure Dippers May React Differently to Morning Blood Pressure Surge . MedicalResearch.com. info:/

  • August 2, 2015
  • 08:13 AM
  • 46 views

Epigenetic Biomarker May Improve Cervical Cancer Screening

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Christos Nikolaidis Ph.D. Laboratory of Pharmacology Medical School, Democritus University of Thrace Dragana, Alexandroupolis Greece Medical Research: What is the background for this study? Response: Epigenetic changes are part of the natural history of cervical neoplasia. Tracking … Continue reading →
The post Epigenetic Biomarker May Improve Cervical Cancer Screening appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Christos Nikolaidis Ph.D. (2015) Epigenetic Biomarker May Improve Cervical Cancer Screening. MedicalResearch.com. info:/

  • August 1, 2015
  • 08:42 PM
  • 67 views

The Idiosyncratic Side of Diagnosis by Brain Scan and Machine Learning

by The Neurocritic in The Neurocritic

R2D3R2D3 recently had a fantastic Visual Introduction to Machine Learning, using the classification of homes in San Francisco vs. New York as their example. As they explain quite simply: In machine learning, computers apply statistical learning techniques to automatically identify patterns in data. These techniques can be used to make highly accurate predictions. You should really head over there right now to view it, because it's very impressive.Computational neuroscience types are using machin........ Read more »

  • August 1, 2015
  • 01:58 PM
  • 66 views

Childhood cancer cells drain immune system’s batteries

by Dr. Jekyll in Lunatic Laboratories

Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for the body’s immune cells, leaving them too physically drained to fight the disease, according to new research. Cancer Research UK-funded scientists have discovered that the cells in neuroblastoma – a rare type of childhood cancer that affects nerve cells – produce a molecule that breaks down arginine, one of the building blocks of proteins and an essential energy source for immune cells.... Read more »

  • August 1, 2015
  • 09:20 AM
  • 54 views

Genes May Explain Why Smarter People Live Longer

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Dr. Rosalind Arden Centre for Philosophy of Natural & Social Science London School of Economics London MedicalResearch: What is the background for this study? What are the main findings? Dr. Arden: We’ve known for a while that … Continue reading →
The post Genes May Explain Why Smarter People Live Longer appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Dr. Rosalind Arden. (2015) Genes May Explain Why Smarter People Live Longer. MedicalResearch.com. info:/

  • August 1, 2015
  • 07:25 AM
  • 40 views

Patients With Blood Cancers May Need More Support At End Of Life

by Marie Benz in MedicalResearch.com

MedicalResearch.com Interview with: Prof David C Currow Discipline of Palliative and Supportive Services Flinders University Adelaide, SA, Australia Medical Research: What is the background for this study? Prof. Currow: This study grew out of a desire to better understand the … Continue reading →
The post Patients With Blood Cancers May Need More Support At End Of Life appeared first on MedicalResearch.com Medical Research Interviews and News.
... Read more »

Prof David C Currow. (2015) Patients With Blood Cancers May Need More Support At End Of Life. MedicalResearch.com. info:/

  • August 1, 2015
  • 03:16 AM
  • 71 views

Methylphenidate: a repairer of the 'oxidative balance' in ADHD?

by Paul Whiteley in Questioning Answers

A fairly quick post for you today based on the findings reported by Esra Guney and colleagues [1] who examined whether markers of oxidative stress - an imbalance "between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage" - might be something to look at when it comes to cases of attention-deficit hyperactivity disorder (ADHD).They concluded that, based on a small-ish sample........ Read more »

Guney, E., Cetin, F., Alisik, M., Tunca, H., Tas Torun, Y., Iseri, E., Isik Taner, Y., Cayci, B., & Erel, O. (2015) Attention Deficit Hyperactivity Disorder and oxidative stress: A short term follow up study. Psychiatry Research. DOI: 10.1016/j.psychres.2015.07.003  

  • July 31, 2015
  • 02:33 PM
  • 88 views

Crystal clear images uncover secrets of hormone receptors

by Dr. Jekyll in Lunatic Laboratories

Many hormones and neurotransmitters work by binding to receptors on a cell’s exterior surface. This activates receptors causing them to twist, turn and spark chemical reactions inside cells. NIH scientists used atomic level images to show how the neuropeptide hormone neurotensin might activate its receptors. Their description is the first of its kind for a neuropeptide-binding G protein-coupled receptor (GPCR), a class of receptors involved in a wide range of disorders and the target of many d........ Read more »

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