A new study from the Max Planck Institute shows how root-associated bacteria can rescue plants from sudden-wilt disease. The authors conducted laboratory and field testing to show that treating seeds with a mixture of six native bacterial species significantly reduces plant mortality.... Read more »
Santhanam R, Luu VT, Weinhold A, Goldberg J, Oh Y, & Baldwin IT. (2015) Native root-associated bacteria rescue a plant from a sudden-wilt disease that emerged during continuous cropping. Proceedings of the National Academy of Sciences of the United States of America. PMID: 26305938
mTOR is dysregulated in a range of tumour types and can be targeted with mTOR inhibitor treatments such as everolimus and sirolimus. Tuberous sclerosis complex (TSC) and sporadic lymphangioleiomyamatosis (LAM) result from mutations in TSC1 or TSC2 that disrupt mTOR signalling (Carsillo et al., 2000, Glasgow et al., 2010). The associated aberrant cell growth, survival and movement results in the formation of slow growing tumours in various tissues and pulmonary cyst formation with loss of pulmona........ Read more »
Goldberg HJ, Harari S, Cottin V, Rosas IO, Peters E, Biswal S, Cheng Y, Khindri S, Kovarik JM, Ma S.... (2015) Everolimus for the treatment of lymphangioleiomyomatosis: a phase II study. The European respiratory journal, 46(3), 783-94. PMID: 26113676
A quote to start:"[1H]MRS [proton magnetic resonance spectroscopy] measures of cortical and subcortical GSH [glutathione] are not a biomarker for ASD [autism spectrum disorder] in intellectually able adult men."So said the study published by Alice Durieux and colleagues  (open-access available here) based on the measurement of "GSH concentrations in the basal ganglia (BG) and the dorsomedial prefrontal cortex of 21 normally intelligent adult males with ASD and 29........ Read more »
Durieux AM, Horder J, Mendez MA, Egerton A, Williams SC, Wilson CE, Spain D, Murphy C, Robertson D, Barker GJ.... (2015) Cortical and subcortical glutathione levels in adults with autism spectrum disorder. Autism research : official journal of the International Society for Autism Research. PMID: 26290215
A recent paper in Science reports the results of a large-scale effort to test reproducibility in psychological science. The results have caused much discussion (as well they should) in both general public and science forums. I thought I would offer my perspective as the lead author of one of the studies that was included in the reproducibility analysis. I had heard about the project even before being contacted to participate and one of the things that appealed to me about it was that they were t........ Read more »
Open Science Collaboration. (2015) Estimating the reproducibility of psychological science. Science, 349(6251). DOI: 10.1126/science.aac4716
Mirman, D., & Magnuson, J. (2008) Attractor dynamics and semantic neighborhood density: Processing is slowed by near neighbors and speeded by distant neighbors. Journal of Experimental Psychology: Learning, Memory, and Cognition, 34(1), 65-79. DOI: 10.1037/0278-7322.214.171.124
Mirman, D. (2010) Effects of near and distant semantic neighbors on word production. Cognitive, Affective, , 11(1), 32-43. DOI: 10.3758/s13415-010-0009-7
Mirman, D., & Graziano, K. (2013) The Neural Basis of Inhibitory Effects of Semantic and Phonological Neighbors in Spoken Word Production. Journal of Cognitive Neuroscience, 25(9), 1504-1516. DOI: 10.1162/jocn_a_00408
MedicalResearch.com Interview with: Daniel Grenier, Ph.D. Professeur titulaire Oral Ecology Research Group, Faculty of Dentistry, and Institute of Nutrition and Functional Foods, Université Laval Quebec City, QC, Canada Medical Research: What is the background for this study? Dr. Grenier: Periodontal … Continue reading →
The post Wild Blueberry Polyphenols May Help Fight Periodontal Disease appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Daniel Grenier, Ph.D. (2015) Wild Blueberry Polyphenols May Help Fight Periodontal Disease . MedicalResearch.com. info:/
MedicalResearch.com Interview with: Simone Ribero, M.D., Ph.D. University of Turin Department of Medical Sciences Turin Italy and King’s College London Department of Twin Research and Genetic Epidemiology St Thomas’ campus London, UK Medical Research: What is the background for this study? … Continue reading →
The post Microscopic Regression in Thin Melanoma May Be Good Prognostic Sign appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Simone Ribero, M.D., Ph.D. (2015) Microscopic Regression in Thin Melanoma May Be Good Prognostic Sign. MedicalResearch.com. info:/
Fuels and fungi have a long-standing and intricate relationship. Before we get into the juicy details, let's examine the players.Traditionally speaking, a fuel is any organic substance (e.g. wood, coal, and oil) containing lots of stored chemical energy within the bonds holding its atoms together. This energy can be released via combustion, which we harness to move cars forward and generate electricity.Fungi are a huge group of organisms largely describable in terms of what they lack: locomotion........ Read more »
Haider R, Ghauri M, SanFilipo J, Jones E, Orem W, Tatu C, Akhtar K, & Akhtar N. (2013) Fungal degradation of coal as a pretreatment for methane production. Fuel, 717-725. DOI: 10.1016/j.fuel.2012.05.015
MedicalResearch.com Interview with: Dr. Jun Wang MD PhD, Assistant Professor Department of Neuroscience and Experimental Therapeutics Interdisciplinary Program in Neuroscience Texas A&M College of Medicine Medical Research: What is the background for this study? Dr. Wang: Alcohol use disorder is … Continue reading →
The post Neurons In Brain Most Affected by Alcohol Identified appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Dr. Jun Wang MD PhD, Assistant Professor. (2015) Neurons In Brain Most Affected by Alcohol Identified. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Kenneth R. Shroyer, MD, PhD The Marvin Kuschner Professor and Chair Department of Pathology Stony Brook Medicine Stony Brook, NY Medical Research: What is the background for this study? What are the main findings? Dr. … Continue reading →
The post Protein Keratin Promotes Cancer Growth and Chemotherapy Resistance appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Kenneth R. Shroyer, MD, PhD. (2015) Protein Keratin Promotes Cancer Growth and Chemotherapy Resistance. MedicalResearch.com. info:/
People diagnosed with schizophrenia critically rely upon treatment with antipsychotic medications to manage their symptoms and help them function at home and in the workplace. But despite their benefits, antipsychotic medications might also have some negative effects on brain structure or function when taken for long periods of time.... Read more »
Vita, A., De Peri, L., Deste, G., Barlati, S., & Sacchetti, E. (2015) The Effect of Antipsychotic Treatment on Cortical Gray Matter Changes in Schizophrenia: Does the Class Matter? A Meta-analysis and Meta-regression of Longitudinal Magnetic Resonance Imaging Studies. Biological Psychiatry, 78(6), 403-412. DOI: 10.1016/j.biopsych.2015.02.008
MedicalResearch.com Interview with: Charlotte Lund Rasmussen Research Unit, Department of Palliative Medicine Bispebjerg Hospital, Copenhagen, Denmark Medical Research: What is the background for this study? What are the main findings? Response: We see that patients with advanced cancer often suffer … Continue reading →
The post Melatonin Did Not Improve Fatigue in Cancer Patients appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Charlotte Lund Rasmussen. (2015) Melatonin Did Not Improve Fatigue in Cancer Patients. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Rashid Bashshur PhD Director of Telemedicine University of Michigan Health System Emeritus Professor of Health Management and Policy University of Michigan, School of Public Health Medical Research: What is the background for this study? What are … Continue reading →
The post Telemedicine May Help Patients Adopt Healthy Lifestyle and Manage Chronic Diseases appeared first on MedicalResearch.com Medical Research Studies with Interviews and New........ Read more »
Dr. Rashid Bashshur PhD. (2015) Telemedicine May Help Patients Adopt Healthy Lifestyle and Manage Chronic Diseases. MedicalResearch.com. info:/
MedicalResearch.com Interview with: Dr. Mila Kingsbury PhD Senior Research Associate at Department of Epidemiology and Community Medicine University of Ottawa Medical Research: What is the background for this study? Dr. Kingsbury: Eating a healthy diet, including enough fruits and … Continue reading →
The post Healthy Diet Not Cure-All For Depression appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Dr. Mila Kingsbury PhD. (2015) Healthy Diet Not Cure-All For Depression. MedicalResearch.com. info:/
It is the first week of school here at Michigan State University, and not surprisingly, we’ve got super high temperatures and crazy humidity. It feels like you’re entering a steam […]... Read more »
G. ZOËGA AND K. A. MURPHY. (2015) Life on the Edge of the Arctic: The Bioarchaeology of the Keldudalur Cemetery in Skagafjörður, Iceland. International Journal of Osteoarchaeology. info:/
From time to time I cover some uncomfortable topics on this blog as a function of what hand the autism research cards deal. Today is another one of those times as I bring to your attention the paper by Cathy Cox and colleagues  and their analysis of death concerns and psychological wellbeing in mothers of children diagnosed with an autism spectrum disorder (ASD).What they observed based on completion of a "fear of death scale" and "measures of death-thought accessibility, positive and negativ........ Read more »
Cox CR, Eaton S, Ekas NV, & Van Enkevort EA. (2015) Death concerns and psychological well-being in mothers of children with autism spectrum disorder. Research in developmental disabilities, 229-238. PMID: 26256841
MedicalResearch.com Interview with: Brian D. Elbel, PhD, MPH Associate professor, Departments of Population Health, Division of Health and Behavior and Medicine, Division of General Internal Medicine Marie Bragg, PhD Assistant professorDepartment of Population Health Jonathan Cantor, MS Department of Population … Continue reading →
The post “Happy Meal” Law Would Decrease Fat, Sugar, Salt and Calories in Kids’ Meals appeared first on MedicalResearch.com Medical Rese........ Read more »
MedicalResearch.com Interview. (2015) "Happy Meal" Law Would Decrease Fat, Sugar, Salt and Calories in Kids' Meals. MedicalResearch.com. info:/
It's easy to understand why so many people have been tempted by the futuristic-looking foc.us brain stimulation headset. The manufacturers promise their product will increase brain speed and plasticity and improve mental abilities such as working memory. What's more, the device uses a technology that's usually described as "non-invasive" – transcranial direct current stimulation, or tDCS for short – to send currents apparently safely into your prefrontal cortex.There is ample lab r........ Read more »
Steenbergen, L., Sellaro, R., Hommel, B., Lindenberger, U., Kühn, S., & Colzato, L. (2015) “Unfocus” on foc.us: commercial tDCS headset impairs working memory. Experimental Brain Research. DOI: 10.1007/s00221-015-4391-9
The world might seem a little grayer than usual when we’re down in the dumps and we often talk about “feeling blue” — new research suggests that the associations we make between emotion and color go beyond mere metaphor. The results of two studies indicate that feeling sadness may actually change how we perceive color. Specifically, researchers found that participants who were induced to feel sad were less accurate in identifying colors on the blue-yellow axis than those who were led to ........ Read more »
MedicalResearch.com Interview with: Dr. John Weiser MD MPH Medical epidemiologist Division of HIV/AIDS Prevention CDC Medical Research: What is the background for this study? What are the main findings? Dr. Weiser: Ryan White was an Indiana teenager diagnosed with AIDS … Continue reading →
The post Poor Patients Receiving Care Through Ryan White Programs Achieve Better HIV Control appeared first on MedicalResearch.com Medical Research Studies with Interviews and News.
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Dr. John Weiser MD MPH. (2015) Poor Patients Receiving Care Through Ryan White Programs Achieve Better HIV Control. MedicalResearch.com. info:/
The 2015 U.S. Tennis Open is in full swing and I ran into an interesting recent manuscript summarizing fatigue in tennis.Fatigue has multiple elements including changes in muscle performance, blood markers of lactic acid and other compounds as well as brain central perception factors.Long multi-set matches can last four or five hours. Obviously, at the end of this type of exertion, players have had to adjust to effects of significant fatigue.Reid and Duffield review the key elements of fatigue i........ Read more »
Reid M, & Duffield R. (2014) The development of fatigue during match-play tennis. British journal of sports medicine. PMID: 24668384
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