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  • October 1, 2014
  • 01:41 PM
  • 29 views

The Ever Plastic Brain and Intellectual Disabilities

by Gabriel in Lunatic Laboratories

The plasticity of the brain is always somewhat of a shock. It's near incredible what the brain can achieve, look at people who have strokes, or any other sort of brain injury and yet still somehow manage to get up and move, or perform tasks. So I guess it should be no surprise, but still amazing that studying mice with a genetic change similar to what is found in Kabuki syndrome (an inherited disease of humans) researchers report they have used an anticancer drug to improve mental function......... Read more »

Hans T. Bjornsson, Joel S. Benjamin, Li Zhang, Jacqueline Weissman, Elizabeth E. Gerber, Yi-Chun Chen, Rebecca G. Vaurio, Michelle C. Potter, Kasper D. Hansen, & Harry C. Dietz. (2014) Histone deacetylase inhibition rescues structural and functional brain deficits in a mouse model of Kabuki syndrome. Science Translational Medicine. info:/10.1126/scitranslmed.3009278

  • October 1, 2014
  • 09:00 AM
  • 52 views

What Is Love, Anyway?

by Bill Sullivan in The 'Scope

Inspired by the recent discovery of a couple still holding hands after 700 years, this article ponders the question, "What Is Love, Anyway?"... Read more »

Love TM. (2014) Oxytocin, motivation and the role of dopamine. Pharmacology, biochemistry, and behavior, 49-60. PMID: 23850525  

Domingue, B., Fletcher, J., Conley, D., & Boardman, J. (2014) Genetic and educational assortative mating among US adults. Proceedings of the National Academy of Sciences, 111(22), 7996-8000. DOI: 10.1073/pnas.1321426111  

  • September 30, 2014
  • 12:18 AM
  • 57 views

Conscious content

by Janet Kwasniak in Neuro-patch

I have been thinking about some information in a not too recent paper. (see citation below) Panagiotaropoulos and others looked at the location of the content of consciousness in primates. They used binocular flash suppression (BFS) to give two different visual stimulation that compete for a place in the content of consciousness. Here is their […]... Read more »

  • September 29, 2014
  • 06:07 PM
  • 69 views

Cat and Dogs: seeking solutions with sniffing canines and science

by Cobb & Hecht in Do You Believe In Dog?

Hi Mia and Julie,  First of all, I LOVE your blog! After meeting at SPARCS this past summer (summer for us in North America.. I take it summer is just beginning in Australia!), I’ve followed it closely.  You do amazing things for the promotion of  canine science. Serious love. A bit of background for the readers: I’m currently doing my PhD at Dalhousie University in Halifax, Nova Scotia in Canada, under the supervision of Dr. Simon Gadbois. Dr. Gadbois........ Read more »

  • September 29, 2014
  • 05:12 PM
  • 64 views

New Protein Implicated in Alzheimer’s

by Gabriel in Lunatic Laboratories

Alzheimer's prevention has made some strides in recent years. We've even identified some new causes, and in some cases we can do both. In fact, researchers have now shown that low levels of the protein progranulin in the brain can increase the formation of amyloid-beta plaques (a hallmark of Alzheimer's disease). These plaques can cause neuroinflammation, and worsen memory deficits in a mouse model of this condition. Conversely, by using a gene therapy approach to elevate progranulin levels, sci........ Read more »

Minami, S., Min, S., Krabbe, G., Wang, C., Zhou, Y., Asgarov, R., Li, Y., Martens, L., Elia, L., Ward, M.... (2014) Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models. Nature Medicine. DOI: 10.1038/nm.3672  

  • September 29, 2014
  • 10:32 AM
  • 66 views

Family Attachment and the Brain Cingulate Cortex

by William Yates, M.D. in Brain Posts

Healthy family attachment provides a key element for social support and successful interpersonal relationships.Several brain regions as well as hormonal factors appear to modulate positive emotional responses to family members.I have previously reviewed several studies involving the prosocial effects of the hormone oxytocin and the related hormone vasopressin.Nicolas Rusch from the Department of Psychiatry at Ulm University in Germany along with colleagues in Brazil and London recently published........ Read more »

  • September 27, 2014
  • 02:18 PM
  • 91 views

Sometimes choices are not thought out

by Janet Kwasniak in Neuro-patch

In some competitive situations animals can produce random behavior rather than behavior based on prior experience. The anterior cingulate cortex is where strategies based on models of reality and history are generated; switching to random behavior is done by inputs to this part of the brain from the locus coeruleus. This was reported in a […]... Read more »

  • September 27, 2014
  • 08:37 AM
  • 116 views

The Memory Fades, The Emotion Remains

by Neuroskeptic in Neuroskeptic_Discover

People with Alzheimer’s disease can experience severe memory impairments.However, according to a new study, the emotions associated with events can persist long after the events themselves have been forgotten: Feelings Without Memory in Alzheimer Disease In their paper, the researchers, University of Iowa neurologists Edmarie Guzman-Velez and colleagues, showed volunteers a series of emotional video […]The post The Memory Fades, The Emotion Remains appeared first on Neuroskeptic.... Read more »

Guzmán-Vélez E, Feinstein JS, & Tranel D. (2014) Feelings without memory in Alzheimer disease. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 27(3), 117-29. PMID: 25237742  

  • September 26, 2014
  • 08:14 AM
  • 103 views

Anthropomorphic Neuroscience Driven by Researchers with Large TPJs

by The Neurocritic in The Neurocritic

For immediate release — SEPTEMBER 26, 2014Research from the UCL lab of Professor Geraint Rees has proven that the recent craze for suggesting that rats have “regrets” or show “disappointment” is solely due to the size of the left temporal-parietal junction (TPJ) in the human authors of those papers (Cullen et al., 2014). This startling breakthrough was part of a larger effort to associate every known personality trait, political attitude, and individual difference with the size of a un........ Read more »

  • September 26, 2014
  • 08:00 AM
  • 92 views

Breaking Research: Fruit flies provide insights into metabolism and how we age

by Bethany Christmann in Fly on the Wall

Why do we age? It’s more than just a philosophical question; it’s a puzzle that has frustrated scientists for decades. Currently, the most accepted hypothesis is that aging is the result of accumulated damage to our cells during our lifetime. “Accumulated damage” encompasses a variety of things that can go wrong, including DNA mutations, problems […]... Read more »

  • September 25, 2014
  • 10:37 AM
  • 111 views

A New Discovery in the Treatment of Autoimmunity and Chronic Inflammation

by Gabriel in Lunatic Laboratories

Lupus, Type 1 diabetes, and multiple sclerosis are all diseases brought on by autoimmunity — the bodies inability to tell itself apart from foreign invaders. Finding a cure, or even a suitable treatment has been to put it gently a long, painful road, with little to show for it. On the forefront of the war against the body betrayal is immunosuppressants, which with them carry their own set of side effects and in most cases only off mild to moderate relief of symptoms. But that is all changing a........ Read more »

Dubiella C, Cui H, Gersch M, Brouwer AJ, Sieber SA, Krüger A, Liskamp RM, & Groll M. (2014) Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site. Angewandte Chemie (International ed. in English). PMID: 25244435  

  • September 24, 2014
  • 12:37 PM
  • 109 views

Why Women Give Better Gifts

by William Yates, M.D. in Brain Posts

Consumer spending on gifts for birthdays and holidays is a multi-billion dollar big business.Despite this large economic impact, little research examines factors associated with gift recipient satisfaction.Selecting good gifts for others involves a complex social decision-making process related to judging the value hierarchy of others.A study from the Netherlands recently published in the journal PLOS One featured three experiments on gift selection in a series of men and women.The design of the........ Read more »

Pollmann MM, & van Beest I. (2013) Women are better at selecting gifts than men. PloS one, 8(12). PMID: 24386082  

  • September 24, 2014
  • 08:15 AM
  • 69 views

Doing a task while asleep

by Janet Kwasniak in Neuro-patch

A recent paper (citation below) describes subjects working away at a task, categorizing words, while asleep. Here is the abstract: Falling asleep leads to a loss of sensory awareness and to the inability to interact with the environment. While this was traditionally thought as a consequence of the brain shutting down to external inputs, it […]... Read more »

Kouider, S., Andrillon, T., Barbosa, L., Goupil, L., & Bekinschtein, T. (2014) Inducing Task-Relevant Responses to Speech in the Sleeping Brain. Current Biology, 24(18), 2208-2214. DOI: 10.1016/j.cub.2014.08.016  

  • September 23, 2014
  • 01:55 PM
  • 95 views

Lie Detection using Brain Waves: It’s just as creepy as it sounds…

by Gabriel in Lunatic Laboratories

Currently lie detectors (polygraphs) are not admissible in court, this is because (despite what you may read) there is little proof to show that they are much better than a guess — coming in at roughly 50% accuracy. They aren’t really based in science, making them more of a toy. There might just be a new contender in the lie detection department coming soon however, researchers have found that brain activity can be used to tell whether someone recognizes details they encountered in normal, d........ Read more »

  • September 22, 2014
  • 02:17 PM
  • 85 views

Autism and the Low Iron Connection

by Gabriel in Lunatic Laboratories

The topic of autism is a charged one. Maybe it’s because it isn’t a simple diagnosis; there are many roads to autism. Most of them are probably genetic, some of them are likely environmental, and none of them are related to vaccination (sorry to burst your bubble anti vax people, it’s called science). Some new research shows another possible (environmental) cause. The new study shows that mothers of children with autism are significantly less likely to report taking iron supplements before........ Read more »

Rebecca J. Schmidt et al. (2014) Maternal intake of supplemental iron and risk for autism spectrum disorders. American Journal of Epidemiology. info:/

  • September 21, 2014
  • 04:21 PM
  • 6 views

Spatial-temporal resolution plots for neuroscience methods

by Pierre Megevand in Neuroscience and Medicine

You must have seen these plots before, where the temporal resolution of various methods of probing brain function is plotted along one axis and their spatial resolution on the other. Spatial resolution is often approximated in terms of units of the nervous system (from dendritic spines through neurons and cortical columns all the way to lobes … Continue reading →... Read more »

Grinvald, A., & Hildesheim, R. (2004) VSDI: a new era in functional imaging of cortical dynamics. Nature Reviews Neuroscience, 5(11), 874-885. DOI: 10.1038/nrn1536  

Devor, A., Sakadžić, S., Srinivasan, V., Yaseen, M., Nizar, K., Saisan, P., Tian, P., Dale, A., Vinogradov, S., Franceschini, M.... (2012) Frontiers in optical imaging of cerebral blood flow and metabolism. Journal of Cerebral Blood Flow , 32(7), 1259-1276. DOI: 10.1038/jcbfm.2011.195  

  • September 21, 2014
  • 07:21 AM
  • 121 views

Warning: This Post Will Change Your Brain

by Neuroskeptic in Neuroskeptic_Discover

Last week I gave a talk in Brazil called Why Is It So Hard To Think About The Brain?, Well, no sooner have I returned than a story appeared that illustrates my point all too well. A neuroscience paper made headlines around the world on Friday. Here’s Time‘s take: One Dose of Antidepressant Changes the […]The post Warning: This Post Will Change Your Brain appeared first on Neuroskeptic.... Read more »

Schaefer, A., Burmann, I., Regenthal, R., Arélin, K., Barth, C., Pampel, A., Villringer, A., Margulies, D., & Sacher, J. (2014) Serotonergic Modulation of Intrinsic Functional Connectivity. Current Biology. DOI: 10.1016/j.cub.2014.08.024  

  • September 19, 2014
  • 01:21 PM
  • 116 views

New test for Diagnosing Alzheimer’s Early

by Gabriel in Lunatic Laboratories

Alzheimer’s diagnosis is important, like the famous slogan “with a stroke, time lost is brain lost,” detecting alzheimer’s is important in order to stave off cognitive decline. A just like a stroke time lost is brain lost. Unfortunately early diagnosis has been hard to come by, but now researchers say a simple test that combines thinking and movement can help to detect heightened risk for developing Alzheimer’s disease in a person. The best part, they say this will work even before the........ Read more »

  • September 19, 2014
  • 08:00 AM
  • 164 views

Translational Findings: What drunk fruit flies can tell us about alcohol addiction

by Bethany Christmann in Fly on the Wall

A study in 2012 found that approximately 7.2% of adults in the United States have an alcohol use disorder (a term that covers any person for whom their drinking causes distress or harm). That adds up to approximately 17 million Americans! Treatments for alcoholism, such as behavioral therapies or medications, can often be ineffective in […]... Read more »

  • September 19, 2014
  • 12:13 AM
  • 118 views

The neuroscience behind scratching an itch

by William Lu in The Quantum Lobe Chronicles

The beautiful experience of alleviating an itch, the vigorous scratching of skin cells, and the white flakes that float away slowly and gently like a whimsical dream.If only those with chronic itching problems could describe their conditions in such a serene way. In the latest edition of Nature Neuroscience, Diana Bautista and colleagues (2014) review the literature on the underlying mechanism of the itch at the molecular and cellular level within the peripheral and central nervous systems. They........ Read more »

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