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  • February 6, 2016
  • 03:49 PM
  • 27 views

Brain plasticity assorted into functional networks

by Dr. Jekyll in Lunatic Laboratories

Plasticity of the brain, what does that even mean? Well the good news is that it isn’t just a marketing ploy, the brain needs to be “plastic” because we need to be able to adapt. Frankly speaking, the brain still has a lot to learn about itself. Scientists at the Virginia Tech Carilion Research Institute have made a key finding of the striking differences in how the brain’s cells can change through experience.

... Read more »

  • February 6, 2016
  • 07:42 AM
  • 18 views

Domestic Dog

by Jason Organ in Eatlemania!

The Eatles are cleaning the skull of a domestic dog. Come read about osteoporosis research in the Organ Lab at Indiana University School of Medicine... Read more »

Allen MR, Territo PR, Lin C, Persohn S, Jiang L, Riley AA, McCarthy BP, Newman CL, Burr DB, & Hutchins GD. (2015) In Vivo UTE-MRI Reveals Positive Effects of Raloxifene on Skeletal-Bound Water in Skeletally Mature Beagle Dogs. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(8), 1441-4. PMID: 25644867  

Allen MR, McNerny EM, Organ JM, & Wallace JM. (2015) True Gold or Pyrite: A Review of Reference Point Indentation for Assessing Bone Mechanical Properties In Vivo. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 30(9), 1539-50. PMID: 26235703  

  • February 6, 2016
  • 03:27 AM
  • 47 views

Sleep as a target of antibiotic use in chronic fatigue syndrome?

by Paul Whiteley in Questioning Answers

"The primary finding from the study was evidence of an improvement in several objective sleep parameters in participants in whom the increased colonization of lactic acid producing organisms was resolved after antibiotic treatment."Those were the words written by Melinda Jackson and colleagues [1] (open-access) who, during an open-label trial, looked at whether administration of an antibiotic (erythromycin 400 mg) over the course of 6 days might have some important effects on elements of sleep i........ Read more »

  • February 5, 2016
  • 03:27 PM
  • 52 views

Man-made underwater sound may have wider ecosystem effects

by Dr. Jekyll in Lunatic Laboratories

Underwater sound linked to human activity could alter the behaviour of seabed creatures that play a vital role in marine ecosystems, according to new research from the University of Southampton. The study found that exposure to sounds that resemble shipping traffic and offshore construction activities results in behavioural responses in certain invertebrate species that live in the marine sediment.

... Read more »

  • February 5, 2016
  • 03:01 AM
  • 61 views

Vitamin D supplementation and 'clinical improvement' in autism?

by Paul Whiteley in Questioning Answers

"Vitamin D deficiency might contribute to the aetiology of ASD [autism spectrum disorder]. Supplementation of vitamin D3, which is a safe and cost-effective form of treatment, may significantly improve the outcome of some children with ASD, especially younger children."More big words have appeared from a research group who seem to be particularly interested in how vitamin D (the sunshine vitamin/hormone) might have some important links to at least some cases of autism. The findings thi........ Read more »

Feng J, Shan L, Du L, Wang B, Li H, Wang W, Wang T, Dong H, Yue X, Xu Z.... (2016) Clinical improvement following vitamin D3 supplementation in Autism Spectrum Disorder. Nutritional neuroscience. PMID: 26783092  

  • February 4, 2016
  • 04:33 AM
  • 78 views

Establishing environmental exposures as risk factors for bipolar disorder: Difficult.

by Paul Whiteley in Questioning Answers

The findings reported by Ciro Marangoni and colleagues [1] made for some interesting reading recently and their systematic review of longitudinal studies looking at the various environmental exposures put forward as possible risk factors pertinent to the development of bipolar disorder (BD).Trawling through the peer-reviewed material on this topic, the authors were able to 'clump' the various proposed risk factors into one of three categories: "neurodevelopment (maternal influenza during pr........ Read more »

  • February 3, 2016
  • 09:11 PM
  • 76 views

Effect of mobile phone place and its use on fertility of men

by Usman Paracha in SayPeople

Main Point:

Men who use mobile phone more frequently and place their phone close to their groin have higher chances of getting abnormal sperm concentration.

Published in:

Reproductive BioMedicine Online

Study Further:

Researchers have reported that male infertility constitutes about 30% to 40% of all infertility cases. They also reported that studies are showing continuous decline in semen quality since the start of the last century. One of the potential contributing factors in th........ Read more »

Zilberlicht, A., Wiener-Megnazi, Z., Sheinfeld, Y., Grach, B., Lahav-Baratz, S., & Dirnfeld, M. (2015) Habits of cell phone usage and sperm quality – does it warrant attention?. Reproductive BioMedicine Online, 31(3), 421-426. DOI: 10.1016/j.rbmo.2015.06.006  

  • February 3, 2016
  • 03:06 PM
  • 75 views

Investigating potential fetal exposure to antidepressants

by Dr. Jekyll in Lunatic Laboratories

Depression is a serious issue for expecting mothers. Left untreated, depression could have implications for a fetus’s health. But treating the disease during pregnancy may carry health risks for the developing fetus, which makes an expecting mother’s decision whether to take medication a very difficult one. To better understand how antidepressants affect fetuses during pregnancy, scientists studied exposure in mice.

... Read more »

  • February 3, 2016
  • 11:30 AM
  • 73 views

The RAD-57 – Still Unsafe?

by Rogue Medic in Rogue Medic

I decided to look for something I wrote that I have been wrong about. I thought about Masimo and their RAD-57. I had been very critical of Dr. Michael O’Reilly (then Executive Vice President of Masimo Corporation) for being an advocate of bad science, but he has been hired away by Apple.[1] He should be less dangerous with a telephone than he was with the RAD-57. At the time, he wrote –... Read more »

  • February 3, 2016
  • 04:30 AM
  • 80 views

Aiming for the STARS for Chronic Ankle Instability

by Nicole Cattano in Sports Medicine Research (SMR): In the Lab & In the Field

Sensory-targeted rehabilitation strategies (STARS) result in improvements in patient-reported and clinical outcomes. Certain deficits may be specifically targeted by different techniques.... Read more »

  • February 3, 2016
  • 04:29 AM
  • 74 views

Estimated autism rate in 2 regions of Poland

by Paul Whiteley in Questioning Answers

"The average prevalence of ASD [autism spectrum disorder] was 35/10 000 children and was about 4-fold higher in males."I don't have too much to add to the findings reported by Karolina Skonieczna-Żydecka and colleagues [1] who estimated the prevalence of ASD in two regions of Poland: "West Pomeranian and Pomeranian regions." Based on the analysis of data from "Provincial Disability Services Commissions", researchers concluded that approximately 3 children in 1000 in those regions........ Read more »

Skonieczna-Żydecka K, Gorzkowska I, Pierzak-Sominka J, & Adler G. (2016) The Prevalence of Autism Spectrum Disorders in West Pomeranian and Pomeranian Regions of Poland. Journal of applied research in intellectual disabilities : JARID. PMID: 26771078  

  • February 2, 2016
  • 05:20 PM
  • 98 views

How Not to Get Killed by a Cow

by Elizabeth Preston in Inkfish



Between 1993 and 2015, cattle killed 13 people who were out for walks in the United Kingdom. Dozens more walkers received broken bones or other injuries from the animals.

Murderous cattle are an understudied phenomenon, say veterinarian Angharad Fraser-Williams and other researchers at the University of Liverpool in the United Kingdom. So they scoured news articles and scientific literature to learn about cattle attacks over two decades. They turned up some advice for people wishing to av........ Read more »

Fraser-Williams, A., McIntyre, K., & Westgarth, C. (2016) Are cattle dangerous to walkers? A scoping review. Injury Prevention. DOI: 10.1136/injuryprev-2015-041784  

  • February 2, 2016
  • 03:03 PM
  • 88 views

Depressed or inflamed? Inflammation attacks brain’s reward center

by Dr. Jekyll in Lunatic Laboratories

Inflammation is a good thing, it helps the body fight disease, and without it we wouldn't survive. Unfortunately, when inflammation isn't kept under control it can wreak havoc on the body. From potentially causing alzheimer's to arthritis it seems that unchecked inflammation can cause all sorts of issues. In fact, a new study adds to the list of issues out of control inflammation causes in the body.

... Read more »

  • February 2, 2016
  • 04:29 AM
  • 72 views

Risk of cancer in autism: probably not excessive as more data emerge

by Paul Whiteley in Questioning Answers

A quote to begin: "Taken together, there are no published evidence to suggest that there is a high overall concordance between ASD [autism spectrum disorders] and cancer or between ASD and specific cancers."Those words reported by Svend Erik Mouridsen and colleagues [1] (who knows a thing or two about autism research) should offer some relief to both people on the autism spectrum and their loved ones.Based on the analysis of over 100 adults "diagnosed with infantile autism (IA) in........ Read more »

  • February 1, 2016
  • 03:41 PM
  • 74 views

Blood pressure medicine may improve conversational skills of individuals with autism

by Dr. Jekyll in Lunatic Laboratories

An estimated 1 in 68 children in the United States has autism. The neurodevelopmental disorder, which impairs communication and social interaction skills, can be treated with medications and behavioral therapies, though there is no cure. Now, University of Missouri researchers have found that a medication commonly used to treat high blood pressure and irregular heartbeats may have the potential to improve some social functions of individuals with autism.

... Read more »

  • February 1, 2016
  • 04:30 AM
  • 69 views

Should We Check the Checking Age in Youth Ice Hockey?

by Jane McDevitt in Sports Medicine Research (SMR): In the Lab & In the Field

Concussion rates in youth ice hockey are nearly 3 times higher during games compared to practice, and 12 to 14 year olds have higher incidence rates compared to 15 to 18 year olds.... Read more »

Kontos, A., Elbin, R., Sufrinko, A., Dakan, S., Bookwalter, K., Price, A., Meehan, W., & Collins, M. (2016) Incidence of Concussion in Youth Ice Hockey Players. PEDIATRICS. DOI: 10.1542/peds.2015-1633  

  • February 1, 2016
  • 02:47 AM
  • 104 views

On (pre)pregnancy obesity and inflammation and offspring autism risk

by Paul Whiteley in Questioning Answers

At the time of writing this [long read] post there has been a flurry of autism research articles making news.The headline: 'Scientists create the first ever autistic monkeys' referring to the work published by Liu and colleagues [1] who reported on "lentivirus-based transgenic cynomolgus monkeys (Macaca fascicularis) expressing human MeCP2 in the brain exhibit autism-like behaviours and show germline transmission of the transgene" started the ball rolling. Anyone who knows a little bit about aut........ Read more »

Li, M., Fallin, M., Riley, A., Landa, R., Walker, S., Silverstein, M., Caruso, D., Pearson, C., Kiang, S., Dahm, J.... (2016) The Association of Maternal Obesity and Diabetes With Autism and Other Developmental Disabilities. PEDIATRICS, 137(2), 1-10. DOI: 10.1542/peds.2015-2206  

Choi GB, Yim YS, Wong H, Kim S, Kim H, Kim SV, Hoeffer CA, Littman DR, & Huh JR. (2016) The maternal interleukin-17a pathway in mice promotes autismlike phenotypes in offspring. Science (New York, N.Y.). PMID: 26822608  

  • January 31, 2016
  • 02:57 PM
  • 134 views

The brains of patients with schizophrenia vary depending on the type of schizophrenia

by Dr. Jekyll in Lunatic Laboratories

I have a friend who lost an eye to his brother. Yes, you read that correctly, his brother tried to kill him and in the process he lost his eye. I’ve told this story before, but whenever new schizophrenia research comes out I feel the need to tell it again. While he has forgiven his brother (partly because not long after, he was diagnosed as schizophrenic), he will not be able to see him again until he is released from prison. A tragedy that could’ve been avoided had he been diagnosed sooner......... Read more »

  • January 30, 2016
  • 03:21 PM
  • 121 views

Neurological adaptations to the presence of toxic HIV protein

by Dr. Jekyll in Lunatic Laboratories

Nearly half of HIV infected patients suffer from impaired neurocognitive function. The HIV protein transactivator of transcription (Tat) is an important contributor to HIV neuropathogenesis because it is a potent neurotoxin that continues to be produced despite treatment with antiretroviral therapy.

... Read more »

  • January 30, 2016
  • 01:17 PM
  • 107 views

This Month in Blastocystis Research (JAN 2016)

by Christen Rune Stensvold in Blastocystis Parasite Blog

The first post in the This Month in Blastocystis Research series in 2016 is about Blastocystis epidemiology in India (including IBS patients), views on treatment, and Blastocystis in non-human primates.... Read more »

Pandey PK, Verma P, Marathe N, Shetty S, Bavdekar A, Patole MS, Stensvold CR, & Shouche YS. (2015) Prevalence and subtype analysis of Blastocystis in healthy Indian individuals. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, 296-9. PMID: 25701123  

Kurt Ö, Doğruman Al F, & Tanyüksel M. (2016) Eradication of Blastocystis in humans: Really necessary for all?. Parasitology international. PMID: 26780545  

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